
eJHaem, Journal Year: 2024, Volume and Issue: 5(4), P. 905 - 906
Published: July 12, 2024
Dear Editor, We would like to share ideas on the publication "Severe acute respiratory syndrome coronavirus 2 infection in patients with hematological malignancies Omicron era: failure, need for mechanical ventilation and mortality seronegative seropositive [1]." Researchers compared based severe (SARS-CoV-2) serology order examine outcomes of hematologic malignancy (HM) SARS-CoV-2 from January 2022 March 2023 this retrospective single-center analysis. Of 112 research, 39% had a negative SARS-CoV-2. Comparing individuals patients, findings showed that former were older, higher likelihood lymphoid neoplasm, anti-CD20 medication, more illness. Additionally, Kaplan–Meier study revealed who tested COVID-19 likely experience require ventilation, die virus. This study's approach, which can create biases restrictions data collection analysis, is one its drawbacks. Furthermore, research was carried out at single facility, restrict how broadly results be applied other demographics. it possible sample size insufficient make firm conclusions, particularly when comparing HM those seropositive. did not look into any confounding factors might have affected patients' results. Conducting bigger multicenter prospective validate improve generalizability could next directions area research. analyzing effects various treatment modalities SARS-CoV-2-infected may offer insightful information clinical practice. investigating immune response impact illness progression aid deciphering underlying processes particular cohort. Last but least, examining long-term consequences such as relapse late sequelae, yield crucial patient management post-treatment care. Ideas, writing, analyzing, approval (50%): Hinpetch Daungsupawong. supervision, Viroj Wiwanitkit. The authors declare no conflicts interest. received specific funding work. confirmed ethical statement needed submission. consent trial registration No new are generated study.
Language: Английский