Characterization of nitric oxide in Octopus maya nervous system and its potential role in sensory perception DOI Creative Commons
F. Vergara-Ovalle, Martha León‐Olea,

Eduardo Sánchez-Islas

et al.

Biology Open, Journal Year: 2024, Volume and Issue: 13(12)

Published: Nov. 28, 2024

ABSTRACT The role of nitric oxide as a neurotransmitter in the olfactory and chemoreception systems invertebrates has been well documented. This suggests an early efficient sensory detection system that is evolutionarily preserved various species, including vertebrates invertebrates. Additionally, presence reported molluscs, particularly octopus species. In this work, we present evidence for existence synthase neurons fibers, its anatomical localization nuclei involved chemosensory integration motor responses associated with these processes Octopus maya.

Language: Английский

Recording electrical activity from the brain of behaving octopus DOI Creative Commons
Tamar Gutnick, Andreas Neef, Andrii Cherninskyi

et al.

Current Biology, Journal Year: 2023, Volume and Issue: 33(6), P. 1171 - 1178.e4

Published: Feb. 23, 2023

Language: Английский

Citations

35
Connectomics of the Octopus vulgaris vertical lobe provides insight into conserved and novel principles of a memory acquisition network DOI Creative Commons
Flavie Bidel, Yaron Meirovitch, Richard Schalek

et al.

eLife, Journal Year: 2023, Volume and Issue: 12

Published: July 6, 2023

Here, we present the first analysis of connectome a small volume

Language: Английский

Citations

22
Promoting welfare in the common octopus, Octopus vulgaris: Development of a non-invasive strategy for monitoring Aggregata octopiana parasite load by real-time quantitative PCR (qPCR) DOI
Sara Pérez-Polo, María M. Costa,

Guillermo Chil

et al.

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742643 - 742643

Published: April 1, 2025

Language: Английский

Citations

0
Octopod Hox genes and cephalopod plesiomorphies DOI Creative Commons

Cristian Camilo Barrera Grijalba,

Sonia Victoria Rodríguez Monje, Camino Gestal

et al.

Scientific Reports, Journal Year: 2023, Volume and Issue: 13(1)

Published: Sept. 19, 2023

Abstract Few other invertebrates captivate our attention as cephalopods do. Octopods, cuttlefish, and squids amaze with their behavior sophisticated body plans that belong to the most intriguing among mollusks. Little is, however, known about plan formation role of Hox genes. The latter homeobox genes pattern anterior–posterior axis have only been studied in a single decapod species so far. Here, we study developmental ParaHox gene expression Octopus vulgaris. are expressed near-to-staggered fashion, others homologous organs such stellate ganglia, arms, or funnel. As mollusks Hox1 is nascent octopod shell rudiment. While an evolutionarily conserved also some regions considered cephalopod arms funnel molluscan foot. We argue recruited lesser extent into non-related organ systems than previously thought emphasize despite all morphological innovations molecular data still reveal ancestral heritage cephalopods.

Language: Английский

Citations

5
Neurotransmission and neuromodulation systems in the learning and memory network of Octopus vulgaris DOI Creative Commons

Naama Stern‐Mentch,

Gabrielle C. Winters,

Michael Belenky

et al.

Journal of Morphology, Journal Year: 2022, Volume and Issue: 283(5), P. 557 - 584

Published: Feb. 2, 2022

The vertical lobe (VL) in the octopus brain plays an essential role its sophisticated learning and memory. Early anatomical studies suggested that VL is organized a "fan-out fan-in" connectivity matrix comprising only three morphologically identified neuron types; input axons from median superior frontal (MSFL) innervating en passant millions of small amacrine interneurons (AMs), which converge sharply onto large output neurons (LNs). Recent physiological confirmed feedforward excitatory connectivity; glutamatergic synapse at first MSFL-to-AM synaptic layer cholinergic AM-to-LNs synapse. MSFL-to-AMs synapses show robust hippocampal-like activity-dependent long-term potentiation (LTP) transmitter release. 5-HT, octopamine, dopamine nitric oxide modulate short- plasticity. Here, we present comprehensive histolabeling study to better characterize neural elements VL. We generally MSFLs AMs. Intense labeling for NOS activity AMs neurites were in-line with NO-dependent presynaptic LTP mechanism New discoveries here reveal more heterogeneity than previously thought. GABAergic suggest subpopulation inhibitory layer. Clear γ-amino butyric acid cell bodies LNs supported output, yet co-expressed FMRFamide-like neuropeptides, suggesting additional neuromodulatory output. Furthermore, group was glutamatergic. A new cluster cells as "deep nucleus" showed rich catecholaminergic may play intrinsic neuromodulation. In-situ hybridization immunolabeling allowed characterization localization array neuropeptides neuromodulators, likely involved reward/punishment signals. This analysis fast transmission system, together newly found cellular elements, help integrate behavioral, physiological, pharmacological connectome findings into understanding efficient memory network.

Language: Английский

Citations

8
Three-Dimensional Molecular Atlas of Octopus Arm Neuroanatomy Highlights Spatial and Functional Complexity DOI Creative Commons
Gabrielle C. Winters,

Sarah E. Giancola-Detmering,

Caleb J. Bostwick

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: April 17, 2024

Abstract Octopus arms, notable for their complex anatomy and remarkable flexibility, have sparked significant interest within the neuroscience community. However, there remains a dearth of knowledge about molecular functional identities various cell types in arm’s nervous system. To address this gap, we used hybridization chain reaction (HCR) to identify distinct neuronal arms pygmy octopus, bocki , including putative dopaminergic, octopaminergic, serotonergic, GABAergic, glutamatergic, cholinergic, peptidergic neurons. We obtained high-resolution multiplexed fluorescent images at 0.28x0.28x1.0 μM voxel size from 10 arm base tip cross sections (each 50 thick) created three-dimensional reconstructions axial ganglia, illustrating spatial distribution multiple populations. Our analysis unveiled anatomically molecularly diverse scattered neurons, while also highlighting populations dense small excitatory neurons that appear uniformly distributed throughout cortical layer. data provide new insights into how different may contribute ability an octopus interact with its environment execute tasks. In addition, our findings establish benchmark future studies, allowing pioneering exploration neuroanatomy, offering exciting avenues invertebrate research.

Language: Английский

Citations

1
Three-dimensional molecular atlas highlights spatial and neurochemical complexity in the axial nerve cord of octopus arms DOI Creative Commons
Gabrielle C. Winters,

Sarah E. Giancola-Detmering,

Caleb J. Bostwick

et al.

Current Biology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

1
Cellular and molecular mechanisms of memory in molluscs DOI

John H. Byrne,

Benny Hochner,

Tal Shomrat

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0
Characterization of nitric oxide in Octopus maya nervous system and its potential role in sensory perception DOI Creative Commons
F. Vergara-Ovalle, Martha León‐Olea,

Eduardo Sánchez-Islas

et al.

Biology Open, Journal Year: 2024, Volume and Issue: 13(12)

Published: Nov. 28, 2024

ABSTRACT The role of nitric oxide as a neurotransmitter in the olfactory and chemoreception systems invertebrates has been well documented. This suggests an early efficient sensory detection system that is evolutionarily preserved various species, including vertebrates invertebrates. Additionally, presence reported molluscs, particularly octopus species. In this work, we present evidence for existence synthase neurons fibers, its anatomical localization nuclei involved chemosensory integration motor responses associated with these processes Octopus maya.

Language: Английский

Citations

0