Pediatric Radiology, Journal Year: 2024, Volume and Issue: 54(11), P. 1785 - 1796
Published: Aug. 21, 2024
Abstract Crohn’s disease (CD) is a chronic inflammatory condition that affects the gastrointestinal tract, particularly ileum and colon. This characterized by recurrent bouts of intestinal inflammation with subsequent bowel wall damage, including scarring (i.e., fibrosis) abnormal smooth muscle proliferation. MR enterography, an MRI examination tailored to assess small bowel, first-line diagnostic tool for diagnosing CD in children, characterization monitoring severity extent, assessment disease-related complications. To date, such evaluations have been mostly qualitative, which can adversely impact performance inter-radiologist agreement. Quantitative methods shown aid evaluation variety medical conditions increasingly investigated children adults CD. In CD, objective techniques used assist diagnosis, treatment response, characterize histologic abnormalities. current work, we will review quantitative detecting measuring active (MRI-based scoring systems, T1 relaxation mapping, diffusion-weighted imaging, intra-voxel incoherent motion, mesenteric phase contrast), damage (magnetization transfer), motility (quantitative cine imaging) emphasis on pediatric population. Graphical
Language: Английский