Treatment of Hepatitis C Virus Infections Among Patients of Ukrainian Origin During the Influx of War Refugees to Poland DOI Open Access
Robert Flisiak, Dorota Zarębska‐Michaluk, Diana Martonik

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(24), P. 7641 - 7641

Published: Dec. 15, 2024

Background: The wave of wartime migration from Ukraine has raised a number concerns about infectious diseases, the prevalence which is higher in than host countries, with hepatitis C virus (HCV) infection being one them. Our analysis aimed to assess percentage HCV-infected Ukrainian refugees under care Polish centers providing antiviral diagnosis and therapy, evaluate their characteristics effectiveness treatment direct-acting drugs (DAAs). Methods: included patients nationality treated for HCV between 2022 2024 hepatology centers. Data were collected retrospectively completed online. Results: In population 3911 chronic DAAs 16 2022–2024, there 429 war Ukraine, accounting 11% total treated. was significantly younger (45.7 vs. 51 years, p < 0.001) had women (50.3% 45.3%, = 0.048) compared patients. Patients origin less advanced liver disease likely have comorbidities need comedications. Coinfection human immunodeficiency more common Ukrainians patients, 16.1% 5.9% (p 0.001). distribution genotypes (GTs) also differed; although GT1b predominated both populations, its frequency (62.3% 44.5%, 0.001), while second most GT3 (30.5% 16.2%, Conclusions: Documented differences patient did not affect exceeded 97% but rate those lost follow-up among

Language: Английский

The Impact of the COVID-19 Pandemic on the Clinical and Epidemiological Profile of Severe Acute Respiratory Infection in Bahia, Brazil: A Comparative Analysis of Pre- and Post-Pandemic Trends DOI Creative Commons
Káriton Magalhães Bronze, Uener Ribeiro dos Santos, Galileu Barbosa Costa

et al.

Viruses, Journal Year: 2025, Volume and Issue: 17(3), P. 389 - 389

Published: March 9, 2025

In recent years, the incidence of Severe Acute Respiratory Infection (SARI) has increased due to emergence SARS-CoV-2. However, impact COVID-19 pandemic extends beyond mortality rates. Recent analyses suggest that introduction and spread SARS-CoV-2 have significantly affected epidemiology other key respiratory viruses, such as influenza virus (FLUV), syncytial (RSV), rhinovirus (RV). These changes raise new questions about dynamics post-COVID-19 infections, well potential alterations in symptom profiles clinical outcomes. this study, we analyzed data from Epidemiological Surveillance Information System Viral Agents (SIVEP-Gripe), established by Brazilian Ministry Health, examine profile SARI before during Brazil. Our reveal a distinct epidemiological pattern, with significant decrease FLUV notifications pandemic, accompanied peaks RSV RV cases late 2020. Additionally, there was shift age distribution viral individuals infected being older than those pandemic. Interestingly, Bahia State resulted reduction frequency symptoms associated non-SARS-CoV-2 SARI, without altering findings circulation contributed shift, particularly for FLUV, RSV, marked fever, dyspnea, distress, need ventilatory support. The underlying mechanisms driving these remain unclear. insights are crucial public health authorities policymakers refine surveillance strategies enhance control measures causing SARI.

Language: Английский

Citations

0
Unraveling Poland’s unprecedented influenza surge in early 2025: increased viral severity or post-pandemic vulnerability? DOI
Piotr Rzymski, Anna Piekarska, Robert Pleśniak

et al.

Pharmacological Reports, Journal Year: 2025, Volume and Issue: unknown

Published: April 24, 2025

Language: Английский

Citations

0
Global burden associated with rare infectious diseases of poverty in 2021: findings from the Global Burden of Disease Study 2021 DOI Creative Commons

Yujia Bao,

Yongxuan Li, Yibin Zhou

et al.

Infectious Diseases of Poverty, Journal Year: 2024, Volume and Issue: 13(1)

Published: Nov. 13, 2024

Rare infectious diseases of poverty (rIDPs) involve more than hundreds tropical diseases, which dominantly affect people living in impoverished and marginalized regions fail to be prioritized the global health agenda. The neglect rIDPs could impede progress toward sustainable development. This study aimed estimate disease burden 2021, would pivotal for setting intervention priorities mobilizing resources globally.

Language: Английский

Citations

3
Epidemiological characteristics and serological survey of mumps 15 years after MMR vaccine was included in the immunization program DOI Creative Commons
Xiaoying Gong,

Quanjun Fang,

Wangfeng Zheng

et al.

Journal of Medical Virology, Journal Year: 2024, Volume and Issue: 96(8)

Published: Aug. 1, 2024

Mumps is a vaccine-preventable acute viral infectious disease. To understand the incidence of mumps and population immunity in Quzhou City after measles rubella vaccine (MMR) was included immunization program, we analyzed epidemiological characteristics cases from 2009 to 2023 cross-sectional serosurvey IgG antibodies conducted 2024. We found that 15 years MMR significantly reduced all populations, but remained highest vaccinated children aged 0-12 years. Vaccine escape may explain high highly populations. Updating vaccines or developing new targets multiple genotypes be necessary improve effectiveness against infection fully control infections outbreaks. The positive rate concentration antibody were inconsistent with data. not an ideal substitute for cannot used accurately predict whether target susceptible protected. Natural provide longer-lasting than vaccination.

Language: Английский

Citations

1
Trends in Hospitalizations of Patients with Hepatitis C Virus in Poland between 2012 and 2022 DOI Open Access
Agnieszka Genowska, Dorota Zarębska‐Michaluk, Krystyna Dobrowolska

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(18), P. 5618 - 5618

Published: Sept. 22, 2024

Background: Analyzing hospitalizations of patients with hepatitis C virus (HCV) infection is essential for an effective action plan to eliminate as a public health threat. This study aimed explore trends in HCV and factors related these hospitalizations. Methods: 11-year retrospective (2012–2022) explored Poland based on data from the Nationwide General Hospital Morbidity Study. Results: The mean age individuals was 55 years, hospitalization rates among men women 15.5 13.7 per 100,000 population, respectively. Hospitalizations were 1.8-fold higher urban residents. most frequent comorbidities digestive (24%) cardiovascular (18%) diseases. During studied period, significantly decreased 31.9 2012 5.0 2022, stays requiring 0–3, 4–7, ≥8 days becoming 8-fold, 6-fold, 4-fold less frequent, flattening apparent across all groups, including children. Conclusions: While significant progress has been made managing Poland, continued efforts are required disparities care sustain momentum toward elimination, particularly through enhanced political commitment implementation comprehensive national screening programs.

Language: Английский

Citations

1
Treatment of Hepatitis C Virus Infections Among Patients of Ukrainian Origin During the Influx of War Refugees to Poland DOI Open Access
Robert Flisiak, Dorota Zarębska‐Michaluk, Diana Martonik

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(24), P. 7641 - 7641

Published: Dec. 15, 2024

Background: The wave of wartime migration from Ukraine has raised a number concerns about infectious diseases, the prevalence which is higher in than host countries, with hepatitis C virus (HCV) infection being one them. Our analysis aimed to assess percentage HCV-infected Ukrainian refugees under care Polish centers providing antiviral diagnosis and therapy, evaluate their characteristics effectiveness treatment direct-acting drugs (DAAs). Methods: included patients nationality treated for HCV between 2022 2024 hepatology centers. Data were collected retrospectively completed online. Results: In population 3911 chronic DAAs 16 2022–2024, there 429 war Ukraine, accounting 11% total treated. was significantly younger (45.7 vs. 51 years, p < 0.001) had women (50.3% 45.3%, = 0.048) compared patients. Patients origin less advanced liver disease likely have comorbidities need comedications. Coinfection human immunodeficiency more common Ukrainians patients, 16.1% 5.9% (p 0.001). distribution genotypes (GTs) also differed; although GT1b predominated both populations, its frequency (62.3% 44.5%, 0.001), while second most GT3 (30.5% 16.2%, Conclusions: Documented differences patient did not affect exceeded 97% but rate those lost follow-up among

Language: Английский

Citations

0