Inflammatory Cells of the Lung: Neutrophils DOI
Gregory P. Downey,

Dallas M. Hyde,

Scott I. Simon

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Cerebromicrovascular mechanisms contributing to long COVID: implications for neurocognitive health DOI Creative Commons
Mónika Fekete, Andrea Ceglédi,

Ágnes Szappanos

et al.

GeroScience, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 7, 2025

Abstract Long COVID (also known as post-acute sequelae of SARS-CoV-2 infection [PASC] or post-COVID syndrome) is characterized by persistent symptoms that extend beyond the acute phase infection, affecting approximately 10% to over 30% those infected. It presents a significant clinical challenge, notably due pronounced neurocognitive such brain fog. The mechanisms underlying these effects are multifactorial, with mounting evidence pointing central role cerebromicrovascular dysfunction. This review investigates key pathophysiological contributing cerebrovascular dysfunction in long and their impacts on health. We discuss how endothelial tropism direct vascular trigger dysfunction, impaired neurovascular coupling, blood–brain barrier disruption, resulting compromised cerebral perfusion. Furthermore, appears induce mitochondrial enhancing oxidative stress inflammation within cells. Autoantibody formation following also potentially exacerbates injury, chronic ongoing compromise. These factors collectively contribute emergence white matter hyperintensities, promote amyloid pathology, may accelerate neurodegenerative processes, including Alzheimer’s disease. emphasizes critical advanced imaging techniques assessing health need for targeted interventions address complications. A deeper understanding essential advance treatments mitigate its long-term consequences.

Language: Английский

Citations

2
NETosis: A Key Player in Autoimmunity, COVID-19, and Long COVID DOI Creative Commons
Diana M. Monsalve, Yeny Acosta‐Ampudia, Nicolás Guerrero Acosta

et al.

Journal of Translational Autoimmunity, Journal Year: 2025, Volume and Issue: 10, P. 100280 - 100280

Published: Feb. 21, 2025

Language: Английский

Citations

0
Post-surgery sequelae unrelated to disease progression and chemotherapy revealed in follow-up of patients with stage III colon cancer DOI Creative Commons
Alexia Mirandola,

Andrei Kudriavtsev,

Catalina Isabel Cofre Muñoz

et al.

EBioMedicine, Journal Year: 2024, Volume and Issue: 108, P. 105352 - 105352

Published: Sept. 19, 2024

Language: Английский

Citations

1
Inflammatory Cells of the Lung: Neutrophils DOI
Gregory P. Downey,

Dallas M. Hyde,

Scott I. Simon

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0