Objectification of Pain in Patients with Endometriosis. (Literature review and own data)

Russian Journal of Human Reproduction, Journal Year: 2025, Volume and Issue: 31(2), P. 62 - 62

Published: April 29, 2025

The article focuses on the of methods for objectifying pain syndrome in patients with endometriosis. Endometriosis-related pain, including dysmenorrhea, dyspareunia, and chronic pelvic is a clinically significant symptom disease that leads to seek medical help significantly reduces their quality life. discusses pathophysiological mechanisms related inflammation, abnormal innervation endometrial foci, peripheral, central cross-sensitization. Special attention paid modern diagnosing caused by endometriosis, use modified scales (PainDetect), analysis biomarkers (neurotransmitters, sex hormones, immune markers metabolites) patient’ biosamples assessment histological features endometriotic lesions. Modern neuroimaging techniques such as MRI tractography, neurography resting-state functional are also described. These allow evaluation presence neuropathic components syndromes associated describes animal models endometriosis highlights potential non-invasive tests assessing humans. It emphasizes need developing actively applying objectification key aspect early diagnosis timely treatment prevent progression.

Language: Английский

Global brain connectivity: Test-retest stability and association with biological and neurocognitive variables

Journal of Neuroscience Methods, Journal Year: 2024, Volume and Issue: 409, P. 110205 - 110205

Published: June 22, 2024

Language: Английский