Postbiotics and their biotherapeutic potential for chronic disease and their feature perspective: a review

Frontiers in Microbiomes, Journal Year: 2025, Volume and Issue: 4

Published: March 3, 2025

Postbiotics, which are bioactive compounds derived from the metabolic processes of probiotics, gaining recognition as a promising alternative for managing chronic diseases without need live microorganisms, positioning them valuable strategy in biotherapeutics that offers both curative and preventive techniques modern medicine. This paper provides comprehensive review potential health benefits postbiotics, particularly concerning noncommunicable like diabetes, cancer, obesity cardiovascular conditions, present significant global challenges. We explore various mechanisms by postbiotics exert their beneficial effects, including immune modulation to enhance body’s response reduce inflammation, well improving gut barrier function maintain integrity prevent increased intestinal permeability. Additionally, antioxidant properties play critical role neutralizing oxidative stress, is linked progression diseases. Despite encouraging insights into benefits, we highlight urgent further research clarify specific roles different postbiotic components. A deeper understanding these essential developing targeted healthcare applications, advancing this knowledge, aim create innovative strategies could significantly outcomes at-risk populations. Ultimately, integrating interventions has improve care contribute overall well-being affected individuals communities.

Language: Английский

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Gut Microbiota Modulation Through Dietary Approaches Targeting Better Health During Metabolic Disorders

Molecular Nutrition & Food Research, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

ABSTRACT The impact of gut microbiota is known to play a significant role in an individual's metabolism and health. Many harmful food products or dietary imbalance adversely affect human health changing lifestyle, environmental factors, habits may have their effect on microbiota. It has emerged that regarded as emerging metabolic organ, which dependent diet its composition. This review discusses the significance lactic acid bacteria prominent inhabitant probiotics, prebiotics, polyphenols improve metabolism. fermented foods important source probiotics bioactive molecules also discussed along with disorders like dyslipidemia, obesity, hypercholesterolemia, cancer, hypertension. Finally, gives insights into effective therapeutic prospects through alterations tackle these disorders.

Language: Английский

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Evidence‐based use of biotics in the management of gastrointestinal disorders in dogs and cats

Veterinary Record, Journal Year: 2024, Volume and Issue: 195(S2), P. 26 - 32

Published: Nov. 1, 2024

ABSTRACT The gut microbiome plays a vital role in the overall health of dogs and cats, particularly their gastrointestinal (GI) health. Imbalances microbiome, termed dysbiosis, are associated with range GI disorders, including diarrhoea chronic enteropathy. Emerging evidence tentatively supports therapeutic use pre‐, pro‐ postbiotics (collectively called biotics) to restore homeostasis manage these conditions, especially due potential antibiotic‐sparing effects. This article explores evidence‐based treatment disorders cats.

Language: Английский

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Carboxymethyl chitosan-dialdehyde glucan/polydopamine carrier targeted delivery Bacillus subtilis on enhancing oral utilization and intestinal colonization in mice

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 280, P. 135574 - 135574

Published: Sept. 11, 2024

Language: Английский

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Therapeutic Potential of the Probiotic Lactiplantibacillus plantarum BX 62 and its Postbiotics in Alleviating Rheumatoid Arthritis in Mice

Current Research in Food Science, Journal Year: 2024, Volume and Issue: 9, P. 100915 - 100915

Published: Jan. 1, 2024

This study comprehensively investigated the probiotic potential of

Language: Английский

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