Surfactant‐Based Polymer Microchip Electrophoresis of Ciprofloxacin Hydrochloride Monohydrate in Unfiltered Milk With Fluorescence Detection

Electrophoresis, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

ABSTRACT This work describes a cross‐shaped PMMA ME system capable of detecting ciprofloxacin hydrochloride monohydrate (CPFH) in unfiltered milk samples. The utilizes BGE consisting primarily the surface‐active agent SDS to solubilize fat and improve zeta potential microchannel surface. A theoretical lumped‐element circuit model for is introduced this calculate migration time CPFH. manuscript improves capabilities PMMA‐based CPFH using an SDS‐based BGE. presented has faster time, higher mean output voltage, thinner full‐width at half‐maximum than previously reported dairy‐based biosensor systems. Most notably, new under 10 min, being associated with milking cattle. also found be able detect presence fat. Discussion included future integration existing high‐sensitivity methodologies place overall system's limit detection below established target. To authors’ knowledge, first account milk.

Language: Английский

Contactless Conductivity Detection for Capillary Electrophoresis—Developments From 2020 to 2024

Electrophoresis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 28, 2024

ABSTRACT The review covering the development of capillary electrophoresis with capacitively coupled contactless conductivity detection from 2020 to 2024 is latest in a series going back 2004. article considers applications employing conventional capillaries and planar lab‐on‐chip devices as well fundamental technical developments detector complete instrumentation.

Language: Английский