Drug delivery systems for wound healing treatment of upper airway injury
Expert Opinion on Drug Delivery,
Journal Year:
2024,
Volume and Issue:
21(4), P. 573 - 591
Published: April 2, 2024
Endotracheal
intubation
is
a
common
procedure
to
maintain
an
open
airway
with
risks
for
traumatic
injury.
Pathological
changes
resulting
from
can
cause
upper
complications,
including
vocal
fold
scarring,
laryngotracheal
stenosis,
and
granulomas
present
symptoms
such
as
dysphonia,
dysphagia,
dyspnea.
Current
intubation-related
injury
treatment
approaches
lack
standardized
guidelines,
relying
on
individual
clinician
experience,
surgical
medical
interventions
have
limitations
carry
risks.
Language: Английский
Laryngeal complications after endotracheal intubation and prone positioning in patients with coronavirus disease 2019
Shiori Aibara,
No information about this author
Masahiro Okada,
No information about this author
Kaori Tanaka‐Nishikubo
No information about this author
et al.
Laryngoscope Investigative Otolaryngology,
Journal Year:
2022,
Volume and Issue:
7(6), P. 1909 - 1914
Published: Oct. 21, 2022
Laryngeal
complications
have
been
reported
after
endotracheal
intubation
and
prone
positioning
in
patients
with
critical
coronavirus
disease
2019
(COVID-19),
but
their
association
is
unclear.
In
this
study,
we
investigated
the
rate
of
laryngeal
COVID-19
compared
to
an
alternative
condition
(control
group).
Language: Английский
Laryngotracheal Complications after Intubation for COVID-19: A Multicenter Study
Life,
Journal Year:
2023,
Volume and Issue:
13(5), P. 1207 - 1207
Published: May 18, 2023
Many
of
the
patients
with
COVID-19
have
suffered
respiratory
distress
requiring
prolonged
endotracheal
intubation
(ETI)
resulting
in
laryngotracheal
complication
an
impact
on
breathing,
phonation,
and
swallowing.
Our
aim
is
to
describe
laryngeal
injuries
diagnosed
after
ETI
a
multicentre
study.
Methods:
A
prospective
descriptive
observational
study
was
conducted
from
January
2021
December
2021,
including
complications
due
several
Spanish
hospitals.
We
analyzed
epidemiological
data,
previous
comorbidities,
mean
time
ICU
admission
ETI,
need
for
tracheostomy,
invasive
mechanical
ventilation
until
tracheostomy
or
weaning,
ICU,
type
residual
lesions,
their
treatment.
Results:
obtained
collaboration
nine
hospitals
during
months
2021.
total
49
were
referred.
Tracheostomy
performed
44.9%,
being
late
most
cases
(more
than
7–10
days).
The
number
days
extubation
17.63
days,
main
post-intubation
symptoms
dysphonia,
dyspnea,
dysphagia,
87.8%,
34.7%,
42.9%,
respectively.
frequent
injury
altered
mobility,
present
79.6%.
Statistically,
there
greater
amount
stenosis
delayed
not
observing
data
immobility
alterations.
Conclusion:
long,
according
latest
guidelines,
cycles
pronation.
This
long
may
had
increase
subsequent
sequelae,
such
as
mobility
stenosis.
Language: Английский
Effect of thermal softening of double-lumen endobronchial tubes on postoperative sore throat in patients with prior SARS-CoV-2 infection: a randomized controlled trial
Wenlong Yan,
No information about this author
Jianyue Cai,
No information about this author
Chenchen Zhu
No information about this author
et al.
BMC Anesthesiology,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: Dec. 7, 2023
Abstract
Background
The
incidence
of
postoperative
sore
throat
(POST)
after
tracheal
intubation
using
double-lumen
endobronchial
tubes
(DLTs)
is
higher
in
patients
with
prior
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
infection
than
the
general
population.
This
prospective
trial
was
conducted
to
determine
whether
thermal
softening
DLTs
could
decrease
POST
or
other
airway
injuries
SARS-CoV-2
infection.
Methods
A
total
120
undergoing
thoracoscopic
surgery
were
randomly
assigned
two
groups
(n
=
60
each).
In
group,
distal
portion
DLT
placed
thermostatic
saline
(50
°C)
for
10
min
before
endotracheal
intubation.
control
room
temperature
and
severity
hoarseness
assessed
at
1,
6
24
h
postoperatively.
primary
outcomes
secondary
hoarseness,
vocal
cord
injuries,
hemodynamic
changes
Results
postoperatively
greater
group
[41
(68%)
vs.
22
(37%),
P
0.001].
overall
[46
(76%)
(40%),
<
also
(
0.016).
Vocal
occurred
more
frequently
0.006).
Conclusion
Thermal
can
reduce
insertion.
Trial
registration
has
been
registered
www.chictr.org.cn
(registration
number:
ChiCTR2200066821;
date:
December
19,
2022).
Language: Английский
Tratamento do granuloma laríngeo pós-intubação orotraqueal – revisão integrativa
Débora Belém Sampaio,
No information about this author
Camila de Almeida Freire,
No information about this author
Eduarda Viana Castelo Branco
No information about this author
et al.
Brazilian Journal of Health Review,
Journal Year:
2024,
Volume and Issue:
7(1), P. 4540 - 4555
Published: Feb. 6, 2024
Introdução:
Diante
de
um
cenário
em
que
há
uma
falta
oxigenação
do
sistema
nervoso
central
e
outros
órgãos
sistemas
importantes,
trauma,
a
intubação
orotraqueal
é
medida
irá
salvar
paciente.
Contudo,
não
procedimento
livre
erros,
sendo
o
granuloma
consequência
traumática
ou
demorada
contendo
ampla
variedade
consenso
sobre
os
tratamentos.
Por
esta
razão,
faz-se
necessária
análise
as
distintas
terapêuticas.
Objetivo:
Definir
tratamentos
laríngeo
pós-intubação
através
revisão
integrativa
da
literatura.
Metodologia:
Foi
realizada
literatura
tipo
integrativa.
meio
seleção
estudos
tenham
relevância
sejam
pertinentes
com
título
proposto:
“Tratamentos
pós-intubação:
Uma
literatura”.
A
pesquisa
foi
feita
empregando
plataformas
dados
Scielo,
Pubmed
BVS
utilizando
seguintes
descritores:
“granuloma,
laryngeal”,
“intubation”,
“rapid
sequence
induction
and
intubation”
“intubation,
intratracheal”
“therapeutics”
inglês
“granuloma
laríngeo”,
“intubação”,
“indução
sequência
rápida”,
“intubação
intratraqueal”
“terapêutica”,
português.
Resultados:
Foram
encontrados
total
133
textos.
Destes,
113
foram
excluídos
por
atenderem
aos
critérios
pesquisa,
disponibilizarem
texto
completo
serem
repetidos,
restando
apenas
20
artigos.
Conclusão:
O
laríngeo,
além
ser
orotraqueal,
causa
sintomas
clinicamente
importantes
está
associada
à
diminuição
qualidade
vida.
Embora
exista
inúmeras
estratégias
para
tratamento
granuloma,
acordo
artigos
encontrados,
conservador
ainda
primeira
escolha,
apesar
possibilidade
recidivas,
necessitando
cirúrgico.
Laryngotracheal Stenosis After COVID-19 Infection
Koutou (THE LARYNX JAPAN),
Journal Year:
2024,
Volume and Issue:
36(1), P. 5 - 8
Published: June 1, 2024
Laryngotracheal
stenosis
after
COVID-19
infection
is
typically
caused
by
invasive
mechanical
ventilation
management,
such
as
endotracheal
intubation
or
tracheostomy,
performed
on
the
larynx
and
trachea
while
inflamed
due
to
SARS-CoV-2
infection.
Intubated
patients
infected
with
have
a
higher
incidence
of
laryngotracheal
than
non-COVID-19
patients.
Risk
factors
for
developing
were
found
be
similar
those
intubated
Most
reported
cases
bilateral
vocal
cord
paralysis
appear
posterior
glottic
rather
nerve
paralysis,
based
course
disease.
Treatment
must
emphasize
preservation
laryngeal
function.
Language: Английский