Sensitivity-Enhanced RI Sensor Based on Cascaded Microfiber Mach–Zehnder Interferometers Near the Dispersion Turning Point With Vernier Effect DOI
Xianchao Yang, Chengyuan Hu, Guan Yang

et al.

IEEE Transactions on Instrumentation and Measurement, Journal Year: 2024, Volume and Issue: 73, P. 1 - 8

Published: Jan. 1, 2024

A highly sensitive fiber optic refractive index (RI) sensor with low temperature cross-sensitivity is proposed and demonstrated. The RI sensitivity of Mach-Zehnder interferometer (MZI), which generated by the optical path difference between HE 11 xmlns:xlink="http://www.w3.org/1999/xlink">12 modes in tapered microfiber, can be theoretically improved to ±∞ operating at dispersion turning point (DTP), but limited narrow free spectral range (FSR) fragile structure as waist diameter less than 3 um DTP. To solve problem difficulty micromachining traditional microfiber working DTP, Vernier effect introduced cascading two interferometers (MZIs) larger diameters about 8 um. amplified 20 times reaching 46467 nm/RIU only -1.21×10 -4 RIU/°C aqueous solution. Moreover, magnification factor M adjusted desirably FSR single MZI changing length, then further exceeding 10 xmlns:xlink="http://www.w3.org/1999/xlink">6 nm/RIU, highest all sensors best our knowledge. ultrahigh sensitivity, robust reliable shows great significance for biochemical trace detection, such slight variations caused small biological molecules or extremely concentration samples.

Language: Английский

Research advances on surface plasmon resonance biosensors DOI
Qi Wang, Zi-Han Ren, Wan‐Ming Zhao

et al.

Nanoscale, Journal Year: 2021, Volume and Issue: 14(3), P. 564 - 591

Published: Dec. 9, 2021

The surface plasmon resonance (SPR) phenomenon is of wide interest due to its sensitivity changes in refractive index for the label-free, highly sensitive and rapid detection biomarkers. This paper reviews research progress on SPR biosensors modified with different substrate structures materials, imaging (SPRI), SPR-enhanced electrochemiluminescent (ECL) applications biosensing last five years. focuses application field bio-detection, sensing characteristics prisms, gratings, optical fibers, summarizes analyzes interference resistance sensors modification materials (high-refractive dielectric films, metallic micro- nanostructures, antifouling materials). Considering that an important tool biomedical detection, this SPRI technology detection. In addition, also ECL biosensing. Finally, provides outlook development trends terms portable high-precision sensors, reduction self-loss thin film optimization image processing techniques simplification electrode sensors.

Language: Английский

Citations

160
Photonic Crystal Enhanced Fluorescence: A Review on Design Strategies and Applications DOI Creative Commons
Yanyu Xiong, Skye Shepherd, Joseph Tibbs

et al.

Micromachines, Journal Year: 2023, Volume and Issue: 14(3), P. 668 - 668

Published: March 17, 2023

Nanoscale fluorescence emitters are efficient for measuring biomolecular interactions, but their utility applications requiring single-unit observations is constrained by the need large numerical aperture objectives, intermittency, and poor photon collection efficiency resulting from omnidirectional emission. Photonic crystal (PC) structures hold promise to address aforementioned challenges in enhancement. In this review, we provide a broad overview of PCs explaining structures, design strategies, fabrication techniques, sensing principles. Furthermore, discuss recent PC-enhanced fluorescence-based biosensors incorporated with emerging technologies, including nucleic acids sensing, protein detection, steroid monitoring. Finally, current associated an outlook enhancement photonic-plasmonics coupling point-of-care biosensing as well monitoring analytes biological environmental relevance. The review presents transdisciplinary arena spectroscopy photo-plasmonics, life science research, materials chemistry, cancer diagnostics, internet things.

Language: Английский

Citations

69
Optical fiber SPR biosensor based on gold nanoparticle amplification for DNA hybridization detection DOI
Like Li, Yanan Zhang, Wanlu Zheng

et al.

Talanta, Journal Year: 2022, Volume and Issue: 247, P. 123599 - 123599

Published: May 27, 2022

Language: Английский

Citations

64
Multichannel Fiber Optic SPR Sensors: Realization Methods, Application Status, and Future Prospects DOI
Siqi Zhang, Bo Han, Yanan Zhang

et al.

Laser & Photonics Review, Journal Year: 2022, Volume and Issue: 16(8)

Published: June 9, 2022

Abstract Fiber optic sensors based on surface plasmon resonance (SPR) have demonstrated outstanding performance in biomedical, environmental monitoring, public safety, and other aspects, which provide powerful platforms for qualitative detection quantitative analysis of molecular interactions. Among them, multichannel fiber SPR sensor has become a core tool parallel scenarios due to the superiorities compensating nonspecific binding fluctuations implementing multianalyte determination. The realization methods sensing revolve around microstructures, enhancement by materials, hybrid fiber. applications are liquid refractive index (RI), RI temperature, biochemical molecules, physical parameters. This review thoroughly analyzes compares structure, excitation effect, performance, advantages disadvantages each type sensor. Even though there still some challenges, such as insufficient channels difficulty fabrication, their advancement, efforts multidiscipline including developing high‐performance sensitive films innovating micro–nano fabrication processes will overcome these bottlenecks. Lastly, future development directions from principle, material aspects discussed.

Language: Английский

Citations

54
Research Progress of Resonance Optical Fiber Sensors Modified by Low‐Dimensional Materials DOI
Qi Wang, Xiangyu Yin, Peng Yin

et al.

Laser & Photonics Review, Journal Year: 2023, Volume and Issue: 17(5)

Published: Feb. 1, 2023

Abstract Resonance optical fiber sensors are widely studied for their high sensitivity, small size, and anti‐electromagnetic interference. However, traditional resonance have encountered bottlenecks in the trace detection due to limited localized field intensity low molecules affinity. With development of materials technology, low‐dimensional such as quantum dots, graphene, transition metal sulfides excellent properties carrier mobility, large specific surface area, flexible structure controllable artificial technologies that can also be used synthesize new with desired characteristics, which enhance performance fundamentally. The introduction not only achieve optimization sensors, but make functional realize diversification objects. This paper reviews research progress based on materials. principle indexes related sensing elaborated, modified by introduced. Furthermore, role is summarized, direction production process analyzed, future prospect given.

Language: Английский

Citations

24
Advances in Tapered Optical Fiber Sensor Structures: From Conventional to Novel and Emerging DOI Creative Commons

Wen Zhang,

Xianzheng Lang,

Xuecheng Liu

et al.

Biosensors, Journal Year: 2023, Volume and Issue: 13(6), P. 644 - 644

Published: June 12, 2023

Optical fiber sensors based on tapered optical (TOF) structure have attracted a considerable amount of attention from researchers due to the advantages simple fabrication, high stability, and diverse structures, great potential for applications in many fields such as physics, chemistry, biology. Compared with conventional fibers, TOF their unique structural characteristics significantly improves sensitivity response speed fiber-optic broadens application range. This review presents an overview latest research status sensors. Then, working principle sensors, fabrication schemes novel structures recent years, growing emerging areas are described. Finally, development trends challenges prospected. The objective this is convey perspectives strategies performance optimization design sensing technologies.

Language: Английский

Citations

24
Functional microfluidics: theory, microfabrication, and applications DOI Creative Commons
Mingzhu Xie, Ziheng Zhan, Yinfeng Li

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 6(3), P. 032005 - 032005

Published: Feb. 22, 2024

Abstract Microfluidic devices are composed of microchannels with a diameter ranging from ten to few hundred micrometers. Thus, quite small (10 −9 –10 −18 l) amount liquid can be manipulated by such precise system. In the past three decades, significant progress in materials science, microfabrication, and various applications has boosted development promising functional microfluidic devices. this review, recent on novel functions is presented. First, theory numerical methods for studying performance briefly introduced. Then, fabrication summarized. Next, advances highlighted, including heat sinks, clean water production, chemical reactions, sensors, biomedicine, capillaric circuits, wearable electronic devices, microrobotics. Finally, perspectives challenges future developments This review aims inspire researchers fields—engineering, materials, chemistry, mathematics, physics, more—to collaborate drive forward specifically achieving carbon neutrality.

Language: Английский

Citations

15
A dual-parameter fiber optic sensor based on FP-WGM composite microcavities DOI
Jun Liu, Lu Cai,

Xu-wen Xie

et al.

Optical Fiber Technology, Journal Year: 2025, Volume and Issue: 90, P. 104002 - 104002

Published: Jan. 9, 2025

Language: Английский

Citations

1
Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives DOI Creative Commons
Lili Liang, Fei Xie, Lichuan Jin

et al.

Advanced Sensor Research, Journal Year: 2025, Volume and Issue: unknown

Published: March 5, 2025

Abstract Optical microfiber biosensors have emerged as a revolutionary technology in the biomedical field, offering exceptional sensitivity, specificity, and versatility for biomarkers detection, health monitoring, disease treatment. This comprehensive review explores diverse types of optical based on their fundamental principles underscores pivotal roles advancements. Furthermore, latest advancements challenges faced by applications are scrutinized, insights into future directions, potential breakthroughs, hurdles that need to be addressed arena.

Language: Английский

Citations

1
Plasmonic Fiber Grating Biosensors Demodulated Through Spectral Envelopes Intersection DOI

Maxime Lobry,

Hadrien Fasseaux, Médéric Loyez

et al.

Journal of Lightwave Technology, Journal Year: 2021, Volume and Issue: 39(22), P. 7288 - 7295

Published: Sept. 16, 2021

Gold-coated tilted fiber Bragg gratings (TFBGs) have been highly studied over the last years, mainly for biosensing purposes. They present a comb-like spectrum of narrow-band cladding mode resonances that is often demodulated by tracking change selected peak. In this paper, we report twentyfold more sensitive demodulation method based on intersection upper and lower envelopes gold-coated TFBG spectra. This has successfully applied in experiments towards detection HER2 (Human Epidermal Growth Factor Receptor-2) proteins, relevant biomarker breast cancer. Practical improvements also implemented. First, uniform FBG superimposed to reduce read-out wavelength span 10 nm instead 70 while keeping temperature-compensated measurements. Second, micro-fluidic system implemented smoothly deliver samples sensor. These 3 originalities make sensing platform even attractive use practical applications.

Language: Английский

Citations

49