Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(12)
Published: Dec. 1, 2024
ABSTRACT
Recent
advancements
in
naturally
derived
bioadhesives
have
transformed
their
application
across
diverse
medical
fields,
including
tissue
engineering,
wound
management,
and
surgery.
This
review
focuses
on
the
innovative
development
multifunctional
nature
of
these
bioadhesives,
particularly
emphasizing
role
enhancing
adhesion
performance
wet
environments
optimizing
mechanical
properties
for
use
dynamic
tissues.
Key
areas
covered
include
chemical
physical
mechanisms
adhesion,
incorporation
multi‐adhesion
strategies
that
combine
covalent
non‐covalent
bonding,
bioinspired
designs
mimicking
natural
adhesives
such
as
those
barnacles
mussels.
Additionally,
discusses
emerging
applications
regeneration
musculoskeletal,
cardiac,
neural,
ocular
tissues,
highlighting
potential
bioadhesive‐based
therapies
complex
biological
settings.
Despite
substantial
progress,
challenges
scaling
lab‐based
innovations
clinical
overcoming
environmental
constraints
remain
critical.
Ongoing
research
bioadhesive
technologies
aims
to
bridge
gaps,
promising
significant
improvements
tailored
therapeutic
needs.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(12)
Published: Nov. 25, 2024
ABSTRACT
The
exploration
of
cellulose,
a
natural
polysaccharide
derived
from
renewable
biomass,
has
seen
significant
advancements
in
recent
years
due
to
its
biocompatibility,
biodegradability,
and
versatility.
This
review
paper
comprehensively
covers
the
latest
developments
cellulose
derivatives
as
functional
biomaterials
for
various
biomedical
applications.
Emphasis
is
placed
on
intrinsic
properties
such
mechanical
strength,
thermal
stability,
chemical
modifiability,
which
enable
wide‐ranging
use
drug
delivery
systems,
wound
dressings,
tissue
engineering,
biosensors.
article
further
delves
into
modification
techniques—such
oxidation,
esterification,
etherification—that
enhance
cellulose's
performance,
allowing
it
be
fine‐tuned
specialized
medical
applications,
including
creation
scaffolds
regeneration
smart
materials
responsive
release.
Additionally,
hybridization
with
inorganic
offers
potential
developing
superior
antimicrobial
improved
characteristics.
also
addresses
challenges
processing,
particularly
concerning
optimizing
structure
specific
while
highlighting
future
opportunities
field
personalized
medicine
intelligent
healthcare
devices.
By
examining
both
current
innovations
trends,
this
highlights
growing
importance
sustainable
versatile
resource
industry.
Polymers for Advanced Technologies,
Journal Year:
2024,
Volume and Issue:
35(12)
Published: Dec. 1, 2024
ABSTRACT
Recent
advancements
in
naturally
derived
bioadhesives
have
transformed
their
application
across
diverse
medical
fields,
including
tissue
engineering,
wound
management,
and
surgery.
This
review
focuses
on
the
innovative
development
multifunctional
nature
of
these
bioadhesives,
particularly
emphasizing
role
enhancing
adhesion
performance
wet
environments
optimizing
mechanical
properties
for
use
dynamic
tissues.
Key
areas
covered
include
chemical
physical
mechanisms
adhesion,
incorporation
multi‐adhesion
strategies
that
combine
covalent
non‐covalent
bonding,
bioinspired
designs
mimicking
natural
adhesives
such
as
those
barnacles
mussels.
Additionally,
discusses
emerging
applications
regeneration
musculoskeletal,
cardiac,
neural,
ocular
tissues,
highlighting
potential
bioadhesive‐based
therapies
complex
biological
settings.
Despite
substantial
progress,
challenges
scaling
lab‐based
innovations
clinical
overcoming
environmental
constraints
remain
critical.
Ongoing
research
bioadhesive
technologies
aims
to
bridge
gaps,
promising
significant
improvements
tailored
therapeutic
needs.
