Sympathetic chain reconstruction after failed sympathectomy for hyperhidrosis in regenerative medicine: a narrative review DOI
Francesco Petrella, Federico Raveglia, Andrea Cara

et al.

Regenerative medicine reports ., Journal Year: 2024, Volume and Issue: 1(2), P. 149 - 155

Published: Dec. 1, 2024

Hyperhidrosis is a pathologic condition characterized by abnormal sweating that greater than normally needed for proper thermoregulation. Surgical therapy remains the only effective treatment definitive cure of idiopathic focal hyperhidrosis, although some controversies still exist regarding best operation. The most significant side effect hyperhidrosis surgery compensatory hyperhidrosis. Although severe less frequent form, it results in detrimental on quality life, and restoration pre-surgical advocated affected patients. Sympathetic chain reconstruction represents surgical option managing after failed sympathetic surgery, without results. In this review, we focus experimental clinical data use compensated sympathectomy Regenerative medicine, particularly tissue engineering stem cell technology, offers new therapeutic strategies reconstruction. These may improve or resolve promoting nerve regeneration. However, there are number problems with current research, including inconsistency outcomes, lack long-term follow-up data, insufficient in-depth understanding regenerative medicine techniques. Nonetheless, progress has been made studies. For example, regeneration demonstrated animal models, different methods reconstruction, autologous grafts conduits, have shown studies provide preliminary evidence significance conclusion, development hope patients primary even though treatments not yet achieved desired With further technological technology expected to be means treating thus significantly improving life

Language: Английский

Chitosan-based injectable porous microcarriers with enhanced adipogenic differentiation and angiogenesis for subcutaneous adipose tissue regeneration DOI
Yan Gan,

Haotian Han,

Ying Zhang

et al.

Biomaterials Advances, Journal Year: 2025, Volume and Issue: 169, P. 214174 - 214174

Published: Jan. 5, 2025

Language: Английский

Citations

3
Biomaterials for Corneal Regeneration DOI Creative Commons
Yimeng Li, Zhengke Wang

Advanced Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 31, 2024

Abstract Corneal blindness is a significant reason for visual impairment globally. Researchers have been investigating several methods corneal regeneration in order to cure these patients. Biomaterials are favored due their biocompatibility and capacity promote cell adhesion. A variety of natural synthetic biomaterials, along with decellularized cornea, employed wound healing. Commonly utilized biomaterials encompass proteins such as collagen, gelatin, silk fibroin (SF), well polysaccharides including alginate, chitosan (CS), hyaluronic acid (HA), cellulose. Synthetic primarily consist polyvinyl alcohol (PVA), poly(ε‐caprolactone) (PCL), poly (lactic‐co‐glycolic acid) (PLGA). Bio‐based materials composites hydrogels, films, scaffolds, patches, nanocapsules, other formats the treatment blinding ocular conditions, wounds, ulcers, endothelium, stromal defects. This review attempts summarize vitro, preclinical, clinical trial studies relevant using within last five years, expect that experiences outcomes will inspire provide practical strategies future development regeneration. Furthermore, potential improvements difficulties discussed.

Language: Английский

Citations

3
Sympathetic chain reconstruction after failed sympathectomy for hyperhidrosis in regenerative medicine: a narrative review DOI
Francesco Petrella, Federico Raveglia, Andrea Cara

et al.

Regenerative medicine reports ., Journal Year: 2024, Volume and Issue: 1(2), P. 149 - 155

Published: Dec. 1, 2024

Hyperhidrosis is a pathologic condition characterized by abnormal sweating that greater than normally needed for proper thermoregulation. Surgical therapy remains the only effective treatment definitive cure of idiopathic focal hyperhidrosis, although some controversies still exist regarding best operation. The most significant side effect hyperhidrosis surgery compensatory hyperhidrosis. Although severe less frequent form, it results in detrimental on quality life, and restoration pre-surgical advocated affected patients. Sympathetic chain reconstruction represents surgical option managing after failed sympathetic surgery, without results. In this review, we focus experimental clinical data use compensated sympathectomy Regenerative medicine, particularly tissue engineering stem cell technology, offers new therapeutic strategies reconstruction. These may improve or resolve promoting nerve regeneration. However, there are number problems with current research, including inconsistency outcomes, lack long-term follow-up data, insufficient in-depth understanding regenerative medicine techniques. Nonetheless, progress has been made studies. For example, regeneration demonstrated animal models, different methods reconstruction, autologous grafts conduits, have shown studies provide preliminary evidence significance conclusion, development hope patients primary even though treatments not yet achieved desired With further technological technology expected to be means treating thus significantly improving life

Language: Английский

Citations

0