Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment DOI
Bangrui Yu, Liang Peng, Wenjun Dang

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 461 - 474

Published: April 26, 2025

Language: Английский

Borate ester-crosslinked polysaccharide hydrogel reinforced by proanthocyanidins for oral ulcer therapy DOI

Yan Ge,

Mingjing Wang, Yang Zhou

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114535 - 114535

Published: Jan. 1, 2025

Language: Английский

Citations

1
Coriander‐Derived Exosome‐Like Nanovesicles Laden Hydrogel with Antioxidant Property Accelerates Wound Healing DOI
Ting Wang, Yilong Li, Linlin Hao

et al.

Macromolecular Bioscience, Journal Year: 2025, Volume and Issue: unknown

Published: April 2, 2025

The oxidative balance and inflammatory responses play important roles in wound healing. Plant-derived exosome-like nanovesicles exhibit antioxidant or anti-inflammatory properties. However, their effects underlying molecular mechanisms of action healing remain unclear. Herein, coriander-derived (CDENs) are isolated characterized. It is found that the CDENs can be internalized by HaCaT cells mouse skin tissue, promoting cell migration, scavenging reactive oxygen species (ROS) increasing expression enzymes, effectively relieving inflammation. Furthermore, it designs a CDENs-based hydrogel with sustained CDENs-release effect excellent biocompatibility, explored its potential for use vivo. During different phases healing, CDENs-hydrogel facilitated macrophage M2 polarization inflammation phase, promoted angiogenesis proliferation expedited collagen deposition remodeling phase. Mechanistically, through releasing CDENs, activated Nrf2 signaling pathway, which enhanced enzyme defense system reduced response, ultimately accelerated process. This first report holds great promise as safe effective alternative clinical management.

Language: Английский

Citations

0
Anti-inflammatory and antibacterial hydrogel based on a polymerizable ionic liquid DOI Creative Commons

J A Romero-Antolín,

Natividad Gómez‐Cerezo, Miguel Manzano

et al.

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Cryopreservable, scalable and ready-to-use cell-laden patches for diabetic ulcer treatment DOI
Bangrui Yu, Liang Peng, Wenjun Dang

et al.

Bioactive Materials, Journal Year: 2025, Volume and Issue: 50, P. 461 - 474

Published: April 26, 2025

Language: Английский

Citations

0