Emerging polymeric electrospun fibers: From structural diversity to application in flexible bioelectronics and tissue engineering

Exploration, Journal Year: 2022, Volume and Issue: 2(1)

Published: Jan. 28, 2022

Electrospinning (e-spin) technique has emerged as a versatile and feasible pathway for constructing diverse polymeric fabric structures, which show potential applications in many biological biomedical fields. Owing to the advantages of adjustable mechanics, designable surface multi-functionalization, biomimetic capability natural tissue, remarkable progress been made flexible bioelectronics tissue engineering sensing therapeutic purposes. In this perspective, we review recent works on design hierarchically structured e-spin fibers, well as, fabrication strategies from one-dimensional individual fiber (1D) three-dimensional (3D) arrangements adaptive specific applications. Then, focus most cutting-edge their engineering. Finally, propose future challenges perspectives promoting electrospun fiber-based products toward industrialized, intelligent, multifunctional, safe

Language: Английский

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Progress of Electrospun Nanofibrous Carriers for Modifications to Drug Release Profiles

Journal of Functional Biomaterials, Journal Year: 2022, Volume and Issue: 13(4), P. 289 - 289

Published: Dec. 9, 2022

Electrospinning is an advanced technology for the preparation of drug-carrying nanofibers that has demonstrated great advantages in biomedical field. Electrospun nanofiber membranes are widely used field drug administration due to their such as large specific surface area and similarity extracellular matrix. Different electrospinning technologies can be prepare different structures, those with a monolithic structure, core–shell Janus or porous structure. It also possible controlled-release functions, sustained release, delayed biphasic targeted release. This paper elaborates on drug-loaded using various concludes mechanisms behind controlled release drugs.

Language: Английский

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Recent progress on electrospun nanofibrous polymer membranes for water and air purification: A review

Chemosphere, Journal Year: 2022, Volume and Issue: 310, P. 136886 - 136886

Published: Oct. 17, 2022

Language: Английский

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Tri-Layer Core–Shell Fibers from Coaxial Electrospinning for a Modified Release of Metronidazole

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(11), P. 2561 - 2561

Published: Oct. 31, 2023

Polymers are the backbone of drug delivery. Electrospinning has greatly enriched strategies that have been explored for developing novel delivery systems using polymers during past two decades. In this study, four different kinds polymers, i.e., water-soluble polymer poly (vinyl alcohol) (PVA), insoluble poly(ε-caprolactone) (PCL), Eudragit RL100 (ERL100) and pH-sensitive S100 (ES100) were successfully converted into types tri-layer tri-polymer core-shell fibers through bi-fluid coaxial electrospinning. During process, model metronidazole (MTD) was loaded shell working fluid, which an emulsion. The micro-formation mechanism from emulsion electrospinning proposed. Scanning electron microscope transmission evaluations verified linear morphology resultant their obvious multiple-chamber structures. X-ray diffraction Fourier transform infrared spectroscopy measurements demonstrated MTD presented in amorphous state compatible with three polymeric matrices. vitro dissolution tests could act a synergistic manner prolonged sustained-release profile gut. controlled-release mechanisms suggested detail. protocols reported here pioneer new route creating structure both aqueous organic solvents, strategy advanced sophisticated profiles.

Language: Английский

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Integrated Janus nanofibers enabled by a co-shell solvent for enhancing icariin delivery efficiency

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 658, P. 124180 - 124180

Published: May 4, 2024

Language: Английский

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Enhancing diabetic wound healing: advances in electrospun scaffolds from pathogenesis to therapeutic applications

Frontiers in Bioengineering and Biotechnology, Journal Year: 2024, Volume and Issue: 12

Published: Feb. 5, 2024

Diabetic wounds are a significant subset of chronic characterized by elevated levels inflammatory cytokines, matrix metalloproteinases (MMPs), and reactive oxygen species (ROS). They also associated with impaired angiogenesis, persistent infection, high likelihood hospitalization, leading to substantial economic burden for patients. In severe cases, amputation or even mortality may occur. foot ulcers (DFUs) common complication diabetes, up 25% diabetic patients being at risk developing over their lifetime, more than 70% ultimately requiring amputation. Electrospun scaffolds exhibit structural similarity the extracellular (ECM), promoting adhesion, growth, migration fibroblasts, thereby facilitating formation new skin tissue wound site. The composition size electrospun can be easily adjusted, enabling controlled drug release through fiber structure modifications. porous nature these facilitates gas exchange absorption exudate. Furthermore, surface readily modified impart specific functionalities, making electrospinning nanofiber highly promising treatment wounds. This article provides concise overview healing process in normal pathological mechanisms underlying wounds, including complications such as ulcers. It explores advantages treatment. Additionally, it summarizes findings from various studies on use different types reviews methods loading onto scaffolds. These advancements broaden horizon effectively treating

Language: Английский

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The Potential of Electrospinning to Enable the Realization of Energy-Autonomous Wearable Sensing Systems

ACS Nano, Journal Year: 2024, Volume and Issue: 18(4), P. 2649 - 2684

Published: Jan. 17, 2024

The market for wearable electronic devices is experiencing significant growth and increasing potential the future. Researchers worldwide are actively working to improve these devices, particularly in developing electronics with balanced functionality wearability commercialization. Electrospinning, a technology that creates nano/microfiber-based membranes high surface area, porosity, favorable mechanical properties human vitro vivo applications using broad range of materials, proving be promising approach. Wearable can use mechanical, thermal, evaporative solar energy harvesting technologies generate power future needs, providing more options than traditional sources. This review offers comprehensive analysis how electrospinning used energy-autonomous wireless sensing systems. It provides an overview technology, fundamental mechanisms, scavenging, physiological signal sensing, storage, antenna data transmission. discusses combining textile engineering create superior increase collaboration opportunities. Additionally, challenges related conducting appropriate testing market-ready products also discussed.

Language: Английский

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Review of the Principles, Devices, Parameters, and Applications for Centrifugal Electrospinning

Macromolecular Materials and Engineering, Journal Year: 2022, Volume and Issue: 307(8)

Published: Feb. 25, 2022

Abstract Nanofibers have received extensive attention in the fields of biomedicine, energy catalysis, environmental sciences, and filtration owing to their high specific surface area controllable porosity. Electrospinning centrifugal spinning are two most effective methods for fabricating nanofibers. However, low preparation efficiency electrospinning limits use that technology large‐scale production The morphology nanofibers prepared by is slightly inferior electrospinning. Centrifugal has great industrial application potential. It a new method formed combining electrostatic forces. can efficiently fabricate with good alignment. In particular, polymer melt as precursor effectively address problem solvent residue fiber. this review, working principle device used introduced, influence different components on process discussed, effects parameters fiber properties explained. Then, some applications fabricated described various areas, including energy, filtration. Finally, challenges summarized, perspective future research provided.

Language: Английский

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An Intelligent Wearable Filtration System for Health Management

ACS Nano, Journal Year: 2023, Volume and Issue: 17(7), P. 7035 - 7046

Published: March 30, 2023

To develop intelligent wearable protection systems is of great significance to human health engineering. An ideal air filtration system should possess reliable efficiency, low pressure drop, healthcare monitoring function, and man-machine interactive capability. However, no existing covers all these essential aspects. Herein, we developed an (IWFS) via advanced nanotechnology machine learning. Based on the triboelectric mechanism, fabricated IWFS exhibits a long-lasting high particle efficiency bacteria 99% 100%, respectively, with low-pressure drop 5.8 mmH2O. Correspondingly, charge accumulation optimized (87 nC) increased 3.5 times that pristine nanomesh, providing significant enhancement efficiency. Theoretical principles, including β-phase lower surface potential modified were quantitatively investigated by molecular dynamics simulation, band theory, Kelvin probe force microscopy. Furthermore, endowed function capability through learning wireless transmission technology. Crucial physiological signals people, breath, cough, speaking signals, detected classified, recognition rate 92%; can collect data transmit voice commands in real time without hindrance portable electronic devices. The achieved not only has practical for management but also theoretical value systems.

Language: Английский

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Critical review on membrane designs for enhanced flux performance in membrane distillation

Desalination, Journal Year: 2023, Volume and Issue: 553, P. 116484 - 116484

Published: Feb. 24, 2023

Language: Английский

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