Emergent Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 19, 2024
Language: Английский
Advanced Industrial and Engineering Polymer Research, Journal Year: 2024, Volume and Issue: unknown
Published: May 1, 2024
Bio-based polymers have garnered significant interest across the manufacturing industry, global economy, and various engineering disciplines such as packaging, tissue engineering, controlled drug delivery, wound dressing, textiles. In current era, bio-based polymers, notably polysaccharides, offer a promising platform for constructing intricate versatile structures in biomedical sector. These encompass applications regenerative medicine (TERM), delivery devices, coatings wearable sensors, thanks to their distinctive features inherent biocompatibility, flexibility, stretchability, mechanical strength, renewability, physiological activity, favorable biological environment. this review, we concise overview of diverse types polysaccharide-based composites, properties, interactions with specific cells tissues. The review encompasses recent progress scaffolds designed cartilage, skin, neural, vascular, cardiac, bone regeneration, employing both conventional modern techniques. Additionally, it delves into development other biodegradable including systems (DDSs), antibacterial on medical electronic devices healthcare Furthermore, also elucidates research directions future perspectives while emphasizing importance regulatory approvals commitment environmental sustainability. This well-organized critical is expected assist practitioners researchers gaining deeper understanding trends, challenges, potential solutions, thereby harnessing immense biomaterials system. utilization polysaccharides sector aligns principles nature, contributing reduction carbon dioxide emissions supporting Sustainable Development Goals United Nations.
Language: Английский
Citations
17
Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113588 - 113588
Published: Jan. 1, 2025
Language: Английский
Citations
1
Computation, Journal Year: 2024, Volume and Issue: 12(4), P. 74 - 74
Published: April 4, 2024
Three-dimensional porous scaffolds are substitutes for traditional bone grafts in tissue engineering (BTE) applications to restore and treat injuries defects. The use of computational modelling is gaining momentum predict the parameters involved healing cell seeding procedures perfusion bioreactors reach final goal optimal growth. Computational based on finite element method (FEM) fluid dynamics (CFD) two standard methodologies utilised investigate equivalent mechanical properties scaffolds, as well flow characteristics inside respectively. success a simulation hinges selection relevant mathematical model with proper initial boundary conditions. This review paper aims provide insights researchers regarding appropriate (FE) models different materials CFD regimes bioreactors. Thus, these FEM/CFD may help create efficient designs by predicting their structural haemodynamic responses prior vitro vivo (TE) applications.
Language: Английский
Citations
5
MedComm – Biomaterials and Applications, Journal Year: 2024, Volume and Issue: 3(1)
Published: Feb. 3, 2024
Abstract The management of peripheral nerve injuries is an important concern due to the their incidence lesions and inappropriate regeneration that follows severe injuries, which ultimately reduces lives patients with this condition. Different strategies have been investigated repair improvement motor sensory regeneration. Although autograft remains gold standard technique, emerging number research articles concerning conduit use reported in last few years. Nerve conduits aim overcome disadvantages, but they satisfy some requirements be suitable for repair. A universal ideal does not exist since properties evaluated case by case; nevertheless, because high biocompatibility biodegradability, natural‐based biomaterials great potential used produce guides. many characteristics synthetic biomaterials, are preferable extraction sources; indeed, these obtained from different renewable sources or food waste, thus reducing environmental impact enhancing sustainability comparison ones. This review highlights recent progress development derivatives injuries.
Language: Английский
Citations
4
Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102049 - 102049
Published: Jan. 1, 2025
Language: Английский
Citations
0
Advanced Composites and Hybrid Materials, Journal Year: 2025, Volume and Issue: 8(2)
Published: Feb. 11, 2025
Language: Английский
Citations
0
Biofabrication, Journal Year: 2024, Volume and Issue: 17(1), P. 015012 - 015012
Published: Oct. 25, 2024
Abstract Combining emulsion templating with additive manufacturing enables the production of inherently porous scaffolds multiscale porosity. This approach incorporates interconnected materials, providing a structure that supports cell ingrowth. However, 3D printing hierarchical structures combine semi-micropores and micropores remains challenging task. Previous studies have demonstrated using carefully adjusted combination light absorbers photoinitiators in resin can produce open surface porosity, sponge-like internal structures, resolution about 150 µ m. In this study, we explored how varying concentrations tartrazine (0, 0.02, 0.04, 0.08 wt%) as absorber affect acrylate-based polymerized medium phase emulsions fabricated via vat photopolymerization. Given importance for tissue engineering regenerative medicine, tested behavior on these 3D-printed disk samples MG-63 cells, examining metabolic activity, adhesion, morphology. The wt% tartrazine-containing sample (008 T) best proliferation adhesion. To show high (HIPE) be used to create complex biomedical applications, trabecular bone based microCT imaging. These were further evaluated migration, followed by analysis after 60 days culture. research demonstrates HIPEs print mimics manufacturing, which could developed lab-on-a-chip models healthy diseased bone.
Language: Английский
Citations
1
Gels, Journal Year: 2024, Volume and Issue: 11(1), P. 17 - 17
Published: Dec. 30, 2024
Hydrogels are a viable option for biomedical applications due to their biocompatibility, biodegradability, and ability incorporate various healing agents while maintaining biological efficacy. This study focused on the preparation characterization of novel hybrid hydrogels enriched with natural algae compound Ulvan potential use in wound dressings. The hydrogel membranes involved multiple methods assess structural, mechanical, chemical properties, such as pH measurements, swelling, moisture content uptake, gel fraction, hydrolytic degradation, protein adsorption denaturation tests, rheological SEM, biocompatibility testing, scratch assay. obtained higher concentration (1 mg/mL) exhibited superior mechanical swelling index 264%, water 55%, lower degradation percentage. In terms inclusion ULV composition enhanced strength, Alginate + PVA 1.0ULV sample demonstrated greatest resistance deformation. All good cell viability above 70% no obvious morphological modifications. addition potentiates regenerative effect membranes. Subsequent studies will focus encapsulating bioactive compounds, investigating release behavior, evaluating active effects.
Language: Английский
Citations
1
Emergent Materials, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 19, 2024
Language: Английский
Citations
0