Recent developments in nanofiber-based fast-disintegrating drug delivery systems DOI
Fuat Topuz, Tamer Uyar

Expert Opinion on Drug Delivery, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Fast-disintegrating electrospun fibers are emerging as innovative systems for oral drug delivery. These possess a high surface area, porosity, and customizable hydrophilicity, which facilitates quick release by disintegrating rapidly in biological fluids or upon contact with water. Hydrophilic polymers cyclodextrins (CDs), either separately combination, frequently utilized to accelerate the disintegration of fibers, enhance solubility hydrophobic drugs, improve bioavailability, leading better therapeutic outcomes. Toward this goal, systematic literature search was conducted identify experimental studies (2019-2025) Web Science, Google Scholar, Scopus using keywords ('fast-disintegrating' OR 'fast-dissolving') AND ('electrospinning' 'electrospun') ('delivery' 'release'). This review examines recent advancements over past five years development fast-disintegrating delivery fibers. It analyzes fiber composition, structural modifications, encapsulation routes, their impact on mucosal Additionally, it addresses challenges faced outlines future directions field.

Language: Английский

Electrospun nanofibers and their application as sensors for healthcare DOI Creative Commons
Yiting Zhao, Jie Huang, Xingjian Yang

et al.

Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13

Published: March 20, 2025

Electrospinning is a type of electrohydrodynamics that utilizes high-voltage electrostatic force to stretch polymer solution into nanofibers under the influence an electric field, with most fibers falling onto collector. This technology favored by researchers across various fields due its simple and inexpensive device for producing in straightforward manner. Nanofibers prepared through electrospinning have high specific surface area porosity. shows extensive potential, especially within biomedical sensors. article provides systematic overview factors influencing electrospinning, parameters process, types electrospun nanofibers, applications field sensors, including wearable pressure glucose The paper summarizes research progress this points out direction development technology, as well future challenges.

Language: Английский

Citations

0
The novel nano-electrospray delivery of curcumin via ultrasound assisted Balangu (Lallemantia royleana) hydrocolloid-chickpea protein interaction DOI
Neda Aliabbasi, Shima Mehrabi,

Mahsa Kheirandish

et al.

Food Chemistry, Journal Year: 2025, Volume and Issue: 484, P. 144388 - 144388

Published: April 17, 2025

Language: Английский

Citations

0
Recent developments in nanofiber-based fast-disintegrating drug delivery systems DOI
Fuat Topuz, Tamer Uyar

Expert Opinion on Drug Delivery, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

Fast-disintegrating electrospun fibers are emerging as innovative systems for oral drug delivery. These possess a high surface area, porosity, and customizable hydrophilicity, which facilitates quick release by disintegrating rapidly in biological fluids or upon contact with water. Hydrophilic polymers cyclodextrins (CDs), either separately combination, frequently utilized to accelerate the disintegration of fibers, enhance solubility hydrophobic drugs, improve bioavailability, leading better therapeutic outcomes. Toward this goal, systematic literature search was conducted identify experimental studies (2019-2025) Web Science, Google Scholar, Scopus using keywords ('fast-disintegrating' OR 'fast-dissolving') AND ('electrospinning' 'electrospun') ('delivery' 'release'). This review examines recent advancements over past five years development fast-disintegrating delivery fibers. It analyzes fiber composition, structural modifications, encapsulation routes, their impact on mucosal Additionally, it addresses challenges faced outlines future directions field.

Language: Английский

Citations

0