Alterations in microbiota of patients with COVID‐19: implications for therapeutic interventions
MedComm,
Journal Year:
2024,
Volume and Issue:
5(4)
Published: March 15, 2024
Severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
recently
caused
a
global
pandemic,
resulting
in
more
than
702
million
people
being
infected
and
over
6.9
deaths.
Patients
with
disease
(COVID-19)
may
suffer
from
diarrhea,
sleep
disorders,
depression,
even
cognitive
impairment,
which
is
associated
long
COVID
during
recovery.
However,
there
remains
no
consensus
on
effective
treatment
methods.
Studies
have
found
that
patients
COVID-19
alterations
microbiota
their
metabolites,
particularly
the
gut,
be
involved
regulation
of
immune
responses.
Consumption
probiotics
alleviate
discomfort
by
inflammation
oxidative
stress.
pathophysiological
process
underlying
alleviation
COVID-19-related
symptoms
complications
targeting
unclear.
In
current
study,
we
summarize
latest
research
evidence
together
SARS-CoV-2
vaccine
use,
focus
relationship
between
use.
This
work
provides
probiotic-based
interventions
improve
regulating
gut
systemic
immunity.
Probiotics
also
used
as
adjuvants
to
efficacy.
Language: Английский
Alterations in Gut Microbiome Composition and Increased Inflammatory Markers in Post-COVID-19 Individuals
Molecular Neurobiology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 18, 2025
Language: Английский
Post-COVID Gut Dysbiosis and Its Role in Persistent Skin Disorders: A Gut–Skin Axis Perspective
Dorra Guermazi,
No information about this author
Elias Guermazi
No information about this author
COVID,
Journal Year:
2025,
Volume and Issue:
5(4), P. 48 - 48
Published: March 31, 2025
The
COVID-19
pandemic
has
led
to
persistent
complications
beyond
the
respiratory
system,
with
emerging
evidence
highlighting
role
of
gut
dysbiosis
in
long
COVID.
Given
established
gut–skin
axis,
alterations
microbiota
post-COVID-19
may
contribute
dermatologic
conditions
such
as
eczema,
acne,
and
rosacea.
This
review
explores
mechanisms
by
which
SARS-CoV-2
disrupts
microbiome,
leading
systemic
inflammation
skin
disease.
Furthermore,
it
examines
potential
interventions,
including
probiotics,
prebiotics,
dietary
modifications,
microbiome-targeted
therapeutic
strategies
for
post-COVID
recovery.
Understanding
this
link
open
new
avenues
treating
chronic
inflammatory
COVID
patients.
Language: Английский
The Interplay of Microbiota, Long COVID, and Musculoskeletal Pain: A Narrative Review
Leila Simorgh,
No information about this author
Rozita Hedayati,
No information about this author
Mina Sadat Mirshoja
No information about this author
et al.
Deleted Journal,
Journal Year:
2024,
Volume and Issue:
1(2)
Published: Sept. 1, 2024
Context:
Long
COVID,
a
condition
that
persists
after
the
acute
phase
of
COVID-19,
poses
significant
burden,
with
10
-
45%
recovered
patients
experiencing
persistent
symptoms.
Among
these,
approximately
46%
report
musculoskeletal
pain.
This
narrative
review
explores
potential
connections
between
gut
microbiota,
and
pain,
aiming
to
introduce
new
therapeutic
avenues
preventive
strategies
for
managing
symptoms
in
COVID
patients.
Evidence
Acquisition:
A
comprehensive
search
was
conducted
using
Google
Scholar,
Lens.org,
ConnectedPaper.com
identify
relevant
articles
published
2019
2024.
Keywords
related
pain
were
used.
Articles
selected
based
on
predefined
inclusion
exclusion
criteria,
their
quality
assessed.
Data
from
synthesized
provide
an
overview
interplay
Results:
Recent
research
highlights
role
microbiota
modulating
immune
responses
systemic
inflammation.
Dysbiosis
has
been
linked
severity
progression
COVID-19
persistence
Individuals
often
experience
new-onset
manifestations,
such
as
joint
myalgia,
chronic
Additionally,
dysbiosis
associated
conditions
like
lower
back
knee
osteoarthritis.
suggests
relationship
problems
general
may
also
extend
patients,
indicating
broader
implications
outcomes.
Therapeutic
targeting
probiotics,
prebiotics,
dietary
interventions,
have
shown
promise
these
improving
overall
health
Conclusions:
The
evidence
underscores
importance
understanding
microbiota-musculoskeletal
nexus
COVID.
Gut
contributes
inflammation,
exacerbating
associations
other
emphasize
need
microbiota-targeted
strategies.
Future
should
focus
elucidating
mechanisms
linking
exploring
gut-brain
axis,
developing
personalized
approaches
modulate
microbiota.
Advancing
our
this
can
pave
way
innovative
address
complex
challenges
posed
by
conditions.
Language: Английский
Acute changes in hippocampal metabolism after anesthesia and surgery: Implications for perioperative neurocognitive disorder
Biochemical and Biophysical Research Communications,
Journal Year:
2024,
Volume and Issue:
736, P. 150492 - 150492
Published: Aug. 3, 2024
Language: Английский
Perspective Chapter: Sequelae and Consequences of COVID-19 in the Paediatric Population
Víctor Manuel Gutiérrez Gómez,
No information about this author
Lenin Ortiz-Ortega,
No information about this author
Beatriz X. Pasco-Velázquez
No information about this author
et al.
IntechOpen eBooks,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 25, 2024
During
the
pandemic
and
in
subsequent
years,
we
observed
that
COVID-19
caused
by
SARS-CoV-2
virus
affected
paediatric
population
different
ways.
In
certain
groups
of
children
adolescents,
social
isolation,
changes
family
dynamics,
increased
exposure
to
technological
screens
diet,
among
others,
have
their
development,
education,
emotional,
physical
aspects,
including
access
immunizations,
medical
surveillance
control.
is
considered
a
generally
benign
pathology
children;
however,
some
patients
develop
well-defined
post-COVID-19
entities:
multisystem
inflammatory
syndrome
(MIS-C)
long
COVID.
this
chapter,
review,
relation
population,
effects
confinement
during
its
development
consequences,
forms
clinical
presentation
entities
MIS-C
COVID,
prevalence,
pathophysiology,
presentation,
evolution,
detection
management
recommendations.
Language: Английский