Impact of Different Traditional Chinese Medicine Constitutions on the Clinical Outcomes of COVID-19 Patients Infected with SARS-CoV-2 Omicron Variant: A Retrospective Observational Study

Infection and Drug Resistance, Journal Year: 2023, Volume and Issue: Volume 16, P. 6333 - 6344

Published: Sept. 1, 2023

Traditional Chinese Medicine (TCM) constitution and disease occurrence, development, prognosis are interrelated. This study aimed to investigate the association between TCM time negative nucleic acid test results in patients with coronavirus 2019 (COVID-19) infected SARS-CoV-2 Omicron variant.We identified COVID-19 (≥18 years) variant collected clinical data, including symptoms, results, constitution. Linear logistic regression analyses explored relationship included 486 COVID-19, a mean age of 40.2 years; 321 (66.0%) men 165 (34.0%) women. Balanced accounted for 43.8%, unbalanced 56.2%. Chi-square showed that different constitutions had significant differences influence symptoms (P < 0.01). After controlling various factors, multiple linear analysis revealed an was significantly positively correlated 0.05). closely related 7-day conversion rate (odds ratio (OR): 0.53, 95% confidence interval (CI): 0.36-0.80, P dividing into deficiency non-deficiency constitution, associated (OR = 0.45, CI: 0.28-0.74, Further damp-heat 0.33, 0.18-0.60, 0.05).In is longer lower rates.

Language: Английский

---

Associations between genetic mutations in different SARS-CoV-2 strains and negative conversion time of viral RNA among imported cases in Hangzhou: A cross-sectional study

Virus Research, Journal Year: 2024, Volume and Issue: 345, P. 199400 - 199400

Published: May 20, 2024

Previous studies on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have focused factors that influence the achievement of negative conversion viral RNA. This study aimed to investigate effects genetic mutations in different SARS-CoV-2 strains time (NCT) among imported cases Hangzhou, Zhejiang Province, China, order provide valuable insights for developing targeted epidemic prevention guidelines.

Language: Английский

---

Evaluation of SARS-CoV-2 Viral Shedding Duration in the Upper Respiratory Specimens and Factors that Predict Prolonged Positivity in Children

Medical Bulletin of Haseki, Journal Year: 2023, Volume and Issue: 61(5), P. 332 - 338

Published: Dec. 1, 2023

Aim: This study evaluated pediatric patient clinical and epidemiological features to identify factors associated with prolonged severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) polymerase chain reaction (PCR) positivity in children. Methods:This retrospective cohort consecutively enrolled SARS-CoV-2-positive cases admitted the University of Health Sciences Turkey, Istanbul Haseki Training Research Hospital between March 31 July 1, 2020.Their PCR results were retrieved from system, time a negative result was calculated.Demographics, disease severity, laboratory radiologic findings patients SARS-CoV-2 within first 14 days (Group 1) after 2) compared. Results:We 258 median age 132.6 months, whom 134 female.The C-reactive protein (CRP) level significantly higher group 1 than 2. A multivariate logistic regression model including age, sex, fever complaints, D-dimer value >0.55 mg/L, high CRP, lymphocyte <1500/uL at admission showed that lymphopenia an independent predictor test positivity. Conclusion:Our indicate children fever, CRP levels, are particularly

Language: Английский

---

Nutritional risk and functionality of children and adolescents hospitalized with COVID-19

European Journal of Pediatrics, Journal Year: 2023, Volume and Issue: 183(3), P. 1223 - 1230

Published: Dec. 13, 2023

Language: Английский

---