Polymeric microneedle advancements in macromolecule drug delivery: current trends, challenges, and future perspectives DOI

Madhuchandra Kenchegowda,

Mohit Angolkar, Umme Hani

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Language: Английский

Interpenetrating Polymer Networks in Biomedical Fields: Recent Advanced and Applications DOI Open Access

Farangis Shahi,

Sara Zarei,

Razhan Salah Othman

et al.

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 1, 2025

ABSTRACT Recent developments in polymer materials have led to an increased implementation of hydrogels biomedical settings, especially the creation smart hydrogels. Traditional single‐network often exhibit challenges, such as poor mechanical strength, insufficient biocompatibility, and slow response rates. To address these issues, researchers introduced Interpenetrating Polymer Network (IPN) hydrogels, which significantly improve strength via topological entanglements physical interactions. This dual‐network design not only enhances biocompatibility but also responsiveness stimuli, endowing with distinctive properties like cell adhesion, conductivity, hemostatic functions, antioxidant abilities, color‐changing properties. The purpose this article is elucidate factors that trigger stimuli IPN their impacts on cellular behavior, various applications they can serve. A comprehensive overview provided regarding classification, mechanisms, performance attributes, related subjects. Ultimately, review emphasizes promise hold fulfilling increasing need for innovative improved features sector.

Language: Английский

Citations

0

Recent Advances in Biomedical Applications of MXene‐Integrated Electrospun Fibers: A Review DOI
Ali Hamzehlouy,

Sara Zarei,

Razhan Salah Othman

et al.

Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(2)

Published: Feb. 1, 2025

ABSTRACT The integration of MXenes into electrospun fibers represents a significant leap forward in advancing biomedical applications. This review delves the synergistic combination and fibers, highlighting their multifaceted capabilities tissue engineering, drug delivery, antimicrobial activity, cancer therapy, biosensing. Exceptional properties MXene, including electrical conductivity, hydrophilicity, mechanical robustness, surface tunability, offer unique advantages when incorporated nanofibrous scaffolds. By enhancing strength, promoting cellular interactions, enabling targeted therapeutic functions, MXene‐based demonstrate immense potential addressing critical challenges biomedicine. provides comprehensive overview recent advances MXene synthesis, incorporation matrices, applications, while also identifying future directions this emerging field.

Language: Английский

Citations

0

A review on microneedle patch as a delivery system for proteins/peptides and their applications in transdermal inflammation suppression DOI
Akshad Balde, Se‐Kwon Kim, Rasool Abdul Nazeer

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 307, P. 141963 - 141963

Published: March 12, 2025

Language: Английский

Citations

0

Polymeric microneedle advancements in macromolecule drug delivery: current trends, challenges, and future perspectives DOI

Madhuchandra Kenchegowda,

Mohit Angolkar, Umme Hani

et al.

Naunyn-Schmiedeberg s Archives of Pharmacology, Journal Year: 2025, Volume and Issue: unknown

Published: April 17, 2025

Language: Английский

Citations

0