Using digital pathology to standardize and automate histological evaluations of environmental samples DOI Creative Commons
Philip Tanabe, Daniel Schlenk, Kristy L. Forsgren

et al.

Environmental Toxicology and Chemistry, Journal Year: 2025, Volume and Issue: 44(2), P. 306 - 317

Published: Jan. 6, 2025

Histological evaluations of tissues are commonly used in environmental monitoring studies to assess the health and fitness status populations or even whole ecosystems. Although traditional histology can be cost-effective, there is a shortage proficient histopathologists results often subjective between operators, leading variance. Digital pathology powerful diagnostic tool that has already significantly transformed research human but rarely been applied studies. analyses slide images introduce possibilities highly standardized histopathological evaluations, as well use artificial intelligence for novel analyses. Furthermore, incorporation digital into using bioindicator species groups such bivalves fish greatly improve accuracy, reproducibility, efficiency This review aims readers how it includes guidelines sample preparation, potential sources error, comparisons

Language: Английский

Revolutionizing Digital Pathology With the Power of Generative Artificial Intelligence and Foundation Models DOI Creative Commons
Asim Waqas, Marilyn M. Bui,

Eric F. Glassy

et al.

Laboratory Investigation, Journal Year: 2023, Volume and Issue: 103(11), P. 100255 - 100255

Published: Sept. 26, 2023

Language: Английский

Citations

33

Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images DOI Creative Commons
Weiwei Wang, Yuanshen Zhao, Lianghong Teng

et al.

Nature Communications, Journal Year: 2023, Volume and Issue: 14(1)

Published: Oct. 11, 2023

Current diagnosis of glioma types requires combining both histological features and molecular characteristics, which is an expensive time-consuming procedure. Determining the tumor directly from whole-slide images (WSIs) great value for diagnosis. This study presents integrated model automatic classification diffuse gliomas annotation-free standard WSIs. Our developed on a training cohort (n = 1362) validation 340), tested internal testing 289) two external cohorts 305 328, respectively). The can learn imaging containing pathological morphology underlying biological clues to achieve achieves high performance with area under receiver operator curve all above 0.90 in classifying major types, identifying grades within type, especially distinguishing genotypes shared features. has potential be used clinical scenarios automated unbiased adult-type gliomas.

Language: Английский

Citations

24

AI in Computational Pathology of Cancer: Improving Diagnostic Workflows and Clinical Outcomes? DOI Creative Commons
Didem Çifçi, Gregory P. Veldhuizen, Sebastian Foersch

et al.

Annual Review of Cancer Biology, Journal Year: 2023, Volume and Issue: 7(1), P. 57 - 71

Published: Jan. 17, 2023

Histopathology plays a fundamental role in the diagnosis and subtyping of solid tumors has become cornerstone modern precision oncology. Histopathological evaluation is typically performed manually by expert pathologists due to complexity visual data. However, last ten years, new artificial intelligence (AI) methods have made it possible train computers perform tasks with high performance, reaching similar levels as experts some applications. In cancer histopathology, these AI tools could help automate repetitive tasks, making more efficient use pathologists’ time. research studies, been shown an astounding ability predict genetic alterations identify prognostic predictive biomarkers directly from routine tissue slides. Here, we give overview recent applications computational pathology, focusing on for that be pivotal identifying clinical better treatment decisions.

Language: Английский

Citations

23

Artificial intelligence in liver cancer — new tools for research and patient management DOI
Julien Caldéraro, Laura Žigutytė, Daniel Truhn

et al.

Nature Reviews Gastroenterology & Hepatology, Journal Year: 2024, Volume and Issue: 21(8), P. 585 - 599

Published: April 16, 2024

Language: Английский

Citations

12

Using digital pathology to standardize and automate histological evaluations of environmental samples DOI Creative Commons
Philip Tanabe, Daniel Schlenk, Kristy L. Forsgren

et al.

Environmental Toxicology and Chemistry, Journal Year: 2025, Volume and Issue: 44(2), P. 306 - 317

Published: Jan. 6, 2025

Histological evaluations of tissues are commonly used in environmental monitoring studies to assess the health and fitness status populations or even whole ecosystems. Although traditional histology can be cost-effective, there is a shortage proficient histopathologists results often subjective between operators, leading variance. Digital pathology powerful diagnostic tool that has already significantly transformed research human but rarely been applied studies. analyses slide images introduce possibilities highly standardized histopathological evaluations, as well use artificial intelligence for novel analyses. Furthermore, incorporation digital into using bioindicator species groups such bivalves fish greatly improve accuracy, reproducibility, efficiency This review aims readers how it includes guidelines sample preparation, potential sources error, comparisons

Language: Английский

Citations

1