Chemotherapy-induced gut microbiome disruption, inflammation, and cognitive decline in female patients with breast cancer

Brain Behavior and Immunity, Journal Year: 2024, Volume and Issue: 120, P. 208 - 220

Published: May 31, 2024

Language: Английский

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Physical activity and cognitive function: moment-to-moment and day-to-day associations

International Journal of Behavioral Nutrition and Physical Activity, Journal Year: 2023, Volume and Issue: 20(1)

Published: Nov. 22, 2023

Abstract Background The beneficial effect of acute physical exercise on cognitive performance has been studied in laboratory settings and long-term longitudinal studies. Less is known about these associations everyday environment a momentary timeframe. This study investigated daily between activity functioning the context life. Methods Middle-aged adults ( n = 291, aged 40–70) were asked to wear accelerometers complete ecological assessments for eight consecutive days. Processing speed visual memory assessed three times per day self-rated evaluations cognition (memory, thinking, sharpness mind) collected each night. number minutes spent above active threshold (active time) maximum vector magnitude counts (the highest intensity obtained) before test at level used as predictors nightly subjective cognition. Analyses done with multilevel linear models. models adjusted temporal contextual factors, age, sex, education, race/ethnicity. Results When participants had more time or higher than their average within 20 60 prior test, they performed better processing task. On days when day, rated evening better. Physical was not associated thinking mind. Conclusions provides novel evidence that outside settings, even small increases boost abilities memory. finding temporary effects consistent research benefits activity.

Language: Английский

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Memory Impairments and Wellbeing in Breast Cancer Patients: A Systematic Review

Journal of Clinical Medicine, Journal Year: 2023, Volume and Issue: 12(22), P. 6968 - 6968

Published: Nov. 7, 2023

Breast cancer is one of the most diagnosed cancers among women. Its effects on cognitive and wellbeing domains have been widely reported in literature, although with inconsistent results. The central goal this review was to identify, women breast cancer, main memory impairments, as measured by objective subjective tools their relationship outcomes. systematic literature search conducted PubMed, Scopus, ProQuest databases. selected studies included 9 longitudinal 10 cross-sectional studies. Although some participants undergoing multimodal therapies, focused chemotherapy's (57.89%; n = 11). pattern results mixed. However, suggested more consistently working deficits patients chemotherapy. In addition, associations identified between outcomes (verbal memory) indicators, particularly depression anxiety. inconsistencies could be justified heterogeneity research designs, measures, sample characteristics. This confirms that empirical evidence needed understand impairments cancer. An effort increase homogeneity study methods should made future

Language: Английский

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A novel ecological momentary assessment app for the investigation of daily cognitive functioning in breast cancer survivors: A feasibility study

Published: April 30, 2024

Purpose: Breast cancer survivors often experience cancer-related cognitive impairment (CRCI), such as problems with memory and attention. However, typical neuropsychological test batteries are unable to capture the day-to-day variability of cognition may be underestimating CRCI. The present study aims assess feasibility, usability, validity a novel ecological momentary assessment (EMA) app cognition.Methods: Nineteen breast 6–36-months post-chemotherapy 26 healthy controls completed NIH Toolbox Cognition Battery. Subsequently, participants EMA (once day, for 30 days) comprising four tasks assessing processing speed, working memory, inhibition, At conclusion app, usability questionnaire on which content analysis was performed. Feasibility assessed against eight criteria, including accessibility, compliance technical smoothness. Convergent construct using Spearman's correlation analyses between toolbox app.Results: Five feasibility criteria were met, including: motivation, participation rate, drop-out, data collection. Additionally, our revealed themes important usability: self-development, altruism, engagement, functionality. Majority moderately positively correlated corresponding constructs (R’s range: 0.55-0.64), indicating, better performance coincided toolbox. Conclusions: Our findings show accessible, motivated complete sessions showed good validity. can used comprehensive measure in survivors.

Language: Английский

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The relationship between psychological distress and cognitive failure among breast cancer survivors: a network analysis

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: July 10, 2024

Background Psychological distress is highly prevalent and has a severe impact on the quality of life among breast cancer survivors. This type associated with cognitive failure. However, previous studies have focused solely total scale scores these two concepts while ignoring unique relationship between specific components. In present study, we utilized network analysis to explore psychological failure in Methods The approach was adopted estimate regularized partial correlation cross-sectional sample 409 All participants were assessed using Depression Anxiety Stress Scale Cognitive Failure Questionnaire. Gaussian Graphical Model employed network, centrality indices, edge weights, providing description characteristics network. Results results indicated that anxiety–stress depression–stress strongest edges community distress. Distractibility–memory Distractibility memory most central nodes, highest expected influence motor coordination acted as important bridge nodes influence. Conclusion played roles activating maintaining Motor identified crucial pathway for Interventions targeting issues might be more effective improving reducing

Language: Английский

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A novel ecological momentary assessment app for the investigation of daily cognitive functioning in breast cancer survivors: A feasibility study

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 10, 2024

Purpose Breast cancer survivors often experience cancer-related cognitive impairment (CRCI), such as problems with memory and attention. However, typical neuropsychological test batteries are unable to capture the day-to-day variability of cognition may be underestimating CRCI. The present study aims assess feasibility, usability, validity a novel ecological momentary assessment (EMA) app cognition. Methods Nineteen breast 6–36-months post-chemotherapy 26 healthy controls completed NIH Toolbox Cognition Battery. Subsequently, participants EMA (once day, for 30 days) comprising four tasks assessing processing speed, working memory, inhibition, At conclusion app, usability questionnaire on which content analysis was performed. Feasibility assessed against eight criteria, including accessibility, compliance technical smoothness. Convergent construct using Spearman's correlation analyses between toolbox app. Results Five feasibility criteria were met, including: motivation, participation rate, drop-out, data collection. Additionally, our revealed themes important usability: self-development, altruism, engagement, functionality. Majority moderately positively correlated corresponding constructs (R’s range: 0.55–0.64), indicating, better performance coincided toolbox. Conclusions Our findings show accessible, motivated complete sessions showed good validity. Implications Cancer Survivors: can used comprehensive measure in survivors.

Language: Английский

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Re: Response to In regard to Ding et al. 2020: “Managing Cancer and Living Meaningfully (CALM) Intervention on Chemotherapy Related Cognitive Impairment in Breast Cancer Survivors”

Integrative Cancer Therapies, Journal Year: 2023, Volume and Issue: 22

Published: Jan. 1, 2023

Language: Английский

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