Asymmetric construction of axial and planar chirality with N-heterocyclic carbene (NHC) organocatalysis
Meng Zhang,
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Xiaoqun Yang,
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Xiaolin Peng
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et al.
Science China Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 30, 2024
Language: Английский
Synthesis, Biological Activity and Mechanism of Action of Pyridine-Containing Arylthiourea Derivatives
Ali Dai,
No information about this author
Zhiguo Zheng,
No information about this author
Dengke Ma
No information about this author
et al.
Journal of Agricultural and Food Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 24, 2025
A
well-developed
root
system
is
a
key
factor
in
improving
crop
quality,
as
it
can
absorb
water,
nourish
and
resist
stress.
series
of
arylthiourea
derivatives
were
synthesized
their
biological
activities
evaluated
this
study.
The
results
indicate
that
compound
A2
significantly
promotes
rice
growth,
exhibiting
effects
more
than
twice
those
the
naphthylacetic
acid
(NAA).
Additionally,
enhances
dry
matter
accumulation
increases
chlorophyll
content,
thereby
disease
resistance
rice.
Preliminary
mechanistic
studies
suggest
mimics
auxin-like
activity,
similar
to
NAA,
interacts
with
SER438
PHE82,
demonstrating
strong
binding
affinity
auxin
receptor
TIR1.
Moreover,
upregulates
auxin-responsive
gene
ARF,
promoting
cell
elongation
accelerating
lateral
development,
leading
larger
Compound
may
have
application
potential
an
agonist,
providing
molecular
basis
for
design
growth
regulators.
Language: Английский
Application of Asymmetric Catalysis in Chiral Pesticide Active Molecule Synthesis
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
72(31), P. 17153 - 17165
Published: July 25, 2024
The
different
configurations
of
chiral
pesticides
generally
have
significant
influence
on
their
biological
activities.
Chiral
agrochemicals
with
high
optical
purities
become
a
prominent
topic
in
the
research
field
new
due
to
advantages
including
lower
toxicity,
higher
efficiency,
and
reduced
residue
levels.
However,
most
commercially
available
that
possess
elements
are
still
used
racemic
forms.
To
date,
asymmetric
catalysis
has
emerged
as
versatile
tool
for
enantioselective
synthesis
various
novel
pesticide
active
molecules.
This
perspective
provides
comprehensive
overview
applications
diverse
catalytic
approaches
facile
preparation
numerous
molecules,
our
own
outlook
future
development
this
highly
direction
is
also
presented
at
end
review.
Language: Английский
Chemical and Biological Investigations of Antiviral Agents Against Plant Viruses Conducted in China in the 21st Century
Genes,
Journal Year:
2024,
Volume and Issue:
15(12), P. 1654 - 1654
Published: Dec. 23, 2024
Research
into
the
biology
of
plant
viruses,
their
mechanisms
pathogenicity,
and
induction
host
resistance
has
laid
a
solid
foundation
for
discovery
antiviral
agents
targets
development
effective
control
technologies.
Additionally,
recent
advancements
in
fields
such
as
chemical
biology,
cheminformatics,
bioinformatics,
synthetic
have
provided
valuable
methods
tools
design
drugs,
synthesis
drug
molecules,
assessment
activity,
investigation
modes
action.
Compared
with
human
viral
diseases,
diseases
presents
greater
challenges,
including
cost-benefit
agents,
simplification
technologies,
effectiveness
treatments.
Therefore,
current
context
complex
outbreaks
severe
damage
caused
by
it
is
crucial
to
delve
deeper
research
agents.
This
review
provides
detailed
overview
biological
characteristics
mode
interaction
between
virus
antivirals,
insights
future
development.
We
believe
this
will
not
only
facilitate
in-depth
analysis
antivirals
crops
but
also
offer
perspectives
use
veterinary
medicine.
Language: Английский