Food Bioengineering,
Journal Year:
2024,
Volume and Issue:
3(4), P. 464 - 481
Published: Dec. 1, 2024
ABSTRACT
Medicinal
and
edible
homologous
(MEHs)
plants
are
valuable
in
medicine
food
science
as
plants.
Saponins,
one
of
the
major
chemical
components
isolated
from
MEHs
plants,
have
significant
antioxidant,
anti‐inflammatory,
antibacterial,
antiviral
biological
activities.
This
paper
provides
an
overview
basic
structure,
properties,
bioactivity
saponins,
development
novel
delivery
systems
for
their
enhanced
bioavailability,
applications
various
fields.
It
also
highlights
innovations
challenges
current
trends
saponin
research
a
basis
safe
effective
natural
active
ingredient
based
on
Through
comprehensive
analysis,
this
aims
to
provide
theoretical
technical
support
further
application
saponins
science.
Journal of Agricultural and Food Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 10, 2025
The
health
benefits
of
oats,
particularly
their
enhanced
nutritional
and
bioactive
properties
when
sprouted,
are
well-documented.
However,
changes
in
steroidal
saponins
during
germination
false
lacking.
This
study
explored
the
influence
various
temperatures
(20,
25,
30
°C)
durations
(1,
3,
5,
7
days)
on
saponin
profiles
both
germinated
false-germinated
oats
assessed
anti-inflammatory
activities.
findings
revealed
that
at
20
°C
for
days
significantly
increased
total
content
to
3265.54
μg/g,
doubling
its
original
concentration.
Notably,
avenacoside
E
(AVE-E),
most
potent
by
an
impressive
21-fold
from
64.02
1421.35
becoming
predominant
following
germination.
Furthermore,
hydrolysis
sugar
moieties
enzymatic
synthesis
were
proposed
as
plausible
secondary
metabolic
pathways
research
provides
first
evidence
can
enhance
levels
properties,
with
proving
more
effective
than
germination,
highlighting
potential
these
methods
further
oats.
Molecules,
Journal Year:
2024,
Volume and Issue:
29(10), P. 2394 - 2394
Published: May 19, 2024
In
recent
years,
there
has
been
a
growing
interest
in
the
use
of
medicinal
plants
and
phytochemicals
as
potential
treatments
for
acne
vulgaris.
This
condition,
characterized
by
chronic
inflammation,
predominantly
affects
adolescents
young
adults.
Conventional
treatment
typically
targets
key
factors
contributing
to
its
development:
proliferation
Cutibacterium
acnes
associated
inflammation.
However,
these
often
involve
potent
drugs.
As
result,
exploration
herbal
medicine
complementary
approach
emerged
promising
strategy.
By
harnessing
therapeutic
properties
phytochemicals,
it
may
be
possible
address
vulgaris
while
minimizing
reliance
on
strong
not
only
offers
benefits
individuals
seeking
alternative
but
also
underscores
importance
natural
remedies
plant
origin
dermatological
care.
The
primary
aim
this
study
was
assess
antimicrobial,
antioxidant,
anti-inflammatory
their
phytochemical
constituents
management
mild
A
comprehensive
search
scientific
databases
conducted
from
2018
September
2023.
findings
review
suggest
that
components
hold
promise
is
crucial
note
further
research
employing
high-quality
evidence
standardized
methodologies
essential
substantiate
efficacy
safety
profiles.
Biomedical & Pharmacology Journal,
Journal Year:
2024,
Volume and Issue:
17(2), P. 713 - 724
Published: June 25, 2024
The
Fabaceae
(Leguminosae)
plant
family
contains
several
species
of
the
Mucuna
Adans.
genus
possessing
therapeutic
potential
and
growing
widely
in
tropical
sub-tropical
regions.
In
this
research,
we
investigated
anti-inflammatory
antioxidant
properties
extract
from
sanjappae
Aitawade
&
S.R.Yadav
seeds.
Initially,
conducted
an
vitro
activity
test
using
bovine
serum
albumin
anti-denaturation
assay
found
promising
dose-dependent
activity.
Subsequently,
performed
vivo
study
on
a
rat
paw
edema
model
induced
by
carrageenan.
Three
different
doses
M.
seed
water
(50,
100
200mg/kg
B/W)
were
used
for
(Oral
administration).
Edema
measurement
was
carried
out
at
0,
2,
4
6
hr
intervals.
Dose
dependent
inhibition
treatment
group
observed
with
maximum
B/W
dose
(53.49%).
Standard
drug
showed
(54.94%)
6hr.
Our
results
also
that,
inhibited
pro-inflammatory
cytokine
TNF-α
increases
IL-10
increased
level
blood
antioxidants.
Phytochemical
analysis
secondary
metabolites
including
polyphenol,
flavonoids,
phytic
acid,
proanthocyanidin,
tannin
saponin
quantified
which
might
be
responsible
component
biological
activities
under
study.
Journal of Cardiovascular Pharmacology,
Journal Year:
2024,
Volume and Issue:
84(5), P. 493 - 495
Published: Aug. 8, 2024
Thrombosis
continues
to
pose
a
significant
challenge
in
cardiovascular
and
cerebrovascular
diseases,
contributing
severe
health
complications
such
as
myocardial
infarction,
acute
ischemic
stroke,
venous
thromboembolism.
Despite
the
wide
array
of
anti-thrombotic
drugs
available,
these
treatments
frequently
carry
substantial
risks,
notably
including
bleeding
complications.
In
this
paper,
we
comment
findings
reported
by
Liu
et
al.
about
potential
protopanaxatriol
saponins
from
panax
notoginseng.
Journal of Food Science,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 12, 2024
Medicago
sativa
L.
is
gaining
attention
as
a
sustainable
plant-based
food
protein.
Alfalfa
saponins
(ASs)
typically
exist
in
glycosylated
form
nature,
which
has
poor
cell
membrane
permeability,
while
the
deglycosylated
may
show
better
bioactivity.
The
AS
was
by
β-glucosidase
from
Aspergillus
niger,
and
chemical
structures
biological
activities,
including
vivo
assays,
of
(DAS)
were
determined.
results
showed
that
half
maximal
inhibitory
concentration
for
2,2-diphenyl-1-picrylhydrazyl
inhibition
DAS
29.5
µg/mL,
demonstrating
significantly
higher
reducing
capacity
compared
to
(p
<
0.05).
induced
33.8%
antibacterial
activity
against
Escherichia
coli
enhanced
proliferation
human
airway
epithelial
cells
(BEAS-2B)
at
125
µg/mL.
In
experiments
on
C57BL/6
mice
fed
high-fat
diet
demonstrated
high-level
treatment
produced
greater
hypolipidemic
effects
Thus,
can
be
deglycosylated,
leads
an
improvement
activity,
particularly
since
exhibits
activity.
PRACTICAL
APPLICATION:
contributed
increased
bioactivity,
its
