Silica‐Mediated Incorporation of Lipase Into The Bulk of a Deep Eutectic Solvent: An Efficient Biocatalytic Phase for Esters Synthesis DOI Open Access
Anna Wolny,

Agata Babiuch,

Piotr Latos

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 17, 2024

Abstract Aiming at sustainable solutions suitable for industrial‐scale catalysis catalytic phase containing lipase and deep eutectic solvent (DES) was designed. To achieve this, both physical chemical immobilizations of lipases were performed on the surface silica carbon materials. The activity developed biosystem tested in biotransformation α‐angelica lactone into butyl levulinate 60 °C. best results achieved Candida antarctica B adsorbed fumed suspended choline chloride: glycerol (1:2) with addition 20 wt% water. Under these conditions 99.9% conversion 100% selectivity to obtained after 45 min. biocatalytic system maintained its up five consecutive reaction cycles full ester. heterogenization enzyme allowed biocatalyst be integrated bulk DES, which includes essential This combination resulted formation a stable easy‐to‐operate where reagents formed second organic phase. integration cost‐effective process efficiency provides greener alternative significant potential industrial use.

Language: Английский

Silica‐Mediated Incorporation of Lipase Into The Bulk of a Deep Eutectic Solvent: An Efficient Biocatalytic Phase for Esters Synthesis DOI Open Access
Anna Wolny,

Agata Babiuch,

Piotr Latos

et al.

ChemCatChem, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 17, 2024

Abstract Aiming at sustainable solutions suitable for industrial‐scale catalysis catalytic phase containing lipase and deep eutectic solvent (DES) was designed. To achieve this, both physical chemical immobilizations of lipases were performed on the surface silica carbon materials. The activity developed biosystem tested in biotransformation α‐angelica lactone into butyl levulinate 60 °C. best results achieved Candida antarctica B adsorbed fumed suspended choline chloride: glycerol (1:2) with addition 20 wt% water. Under these conditions 99.9% conversion 100% selectivity to obtained after 45 min. biocatalytic system maintained its up five consecutive reaction cycles full ester. heterogenization enzyme allowed biocatalyst be integrated bulk DES, which includes essential This combination resulted formation a stable easy‐to‐operate where reagents formed second organic phase. integration cost‐effective process efficiency provides greener alternative significant potential industrial use.

Language: Английский

Citations

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