Metal Organic Framework catalysed Multi Component Reactions towards the synthesis of Pyrans DOI Creative Commons
Subrahmanya Ishwar Bhat, Chinmay Bhat

Heliyon, Journal Year: 2024, Volume and Issue: unknown, P. e41439 - e41439

Published: Dec. 1, 2024

Metal-Organic Frameworks (MOFs) gaining increasing interest in heterogeneous catalysis owing to their advantageous properties such as superior porosity, high surface area, ample catalytic sites. Their can be tailored by varying the metal ions or clusters (nodes) and organic linkers. Magnetically active nano core-shell MOF composites are also discovered for easy separation reuse of catalyst. catalysed multicomponent reactions (MCRs) satisfy several green chemistry principles thus considered a sturdy step towards sustainable chemical synthesis. In this article, synthesis biologically potent pyran scaffolds through MCR approaches have been reviewed. Preparation catalyst, its performance synthesis, reusability has discussed with reaction each example.

Language: Английский

Synthesis and Characterization of a Hercynite-Supported Copper(II) Complex Based on 1,10-Phenanthroline-5,6-dione and Acetylacetone Building Blocks and Its Catalytic Application in Annulation Reactions DOI
Masoud Mohammadi, Ghobad Mansouri

Langmuir, Journal Year: 2024, Volume and Issue: 40(43), P. 22773 - 22786

Published: Oct. 18, 2024

In the present work, a novel Cu(II) complex containing 10-phenanthroline-5,6-dione (phen-dione) and acetylacetone (acac) was prepared via solid-phase synthesis on silica-modified hercynite magnetic nanoparticles (MNPs). The resulting structure underwent thorough structural analysis using diverse instrumental techniques. catalytic potential of synthesized successfully demonstrated in 2-amino-3-cyano-4

Language: Английский

Citations

6
Ultrasound Assisted Domino Strategy for the Synthesis of 2‐Aryl‐4‐(indol‐3‐yl)‐4H‐chromenes under Mild Conditions DOI
Pranab Das, Rana Chatterjee, Rambabu Dandela

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(2)

Published: Jan. 1, 2025

Abstract An efficient and practical approach has been developed for the rapid synthesis of indolyl‐chromene derivatives. Ultrasound assisted three component reaction salicylaldehyde, acetophenone indole leads to indolyl 4 H ‐chromene products in good yields. Pyrrolidine base ethanol medium are employed achieve desired compounds within short time at room temperature. We have also shown catalytic activity usefulness present method by describing TOF TON measurement. Beside includes a metal‐free process, greener solvent, broad range substrate scope, mild conditions.

Language: Английский

Citations

0
Pd-Catalyzed Asymmetric Synthesis of Chiral 2-Trifluoromethyl-4-(indol-3-yl)-4H-chromene Derivatives DOI

Bangzhong Wang,

Luyang Sun, Pengyue Zhang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 29, 2025

This paper presents a new strategy for the construction of chiral 4H-chromene skeleton. A series 2-trifluoromethyl-4-(indol-3-yl)-4H-chromenes were synthesized in moderate to good yields (60-92%) with excellent enantioselectivity (up 97% ee) through palladium-catalyzed asymmetric condensation 2H-chromenes and indoles. These trifluoromethylated, stereochemically rich building blocks hold potential value medicinal chemistry.

Language: Английский

Citations

0
Antioxidant and Antimicrobial Activities of 4H‐Chromene Based Indole – Pyrimidine Hybrids: Synthesis and Molecular Docking Studies DOI

Murali Krishna Vanga,

Rambabu Bhukya,

Vishnu Thumma

et al.

Chemistry & Biodiversity, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 12, 2024

A series of 4H-Chromene Based Indole-Pyrimidine Hybrids synthesized using simple and efficient multicomponent reaction. The title molecules were evaluated for their invitro antioxidant antimicrobial activities. Compounds 8 g containing bromo substituted naphthalene displayed potent activity with IC

Language: Английский

Citations

1
Metal Organic Framework catalysed Multi Component Reactions towards the synthesis of Pyrans DOI Creative Commons
Subrahmanya Ishwar Bhat, Chinmay Bhat

Heliyon, Journal Year: 2024, Volume and Issue: unknown, P. e41439 - e41439

Published: Dec. 1, 2024

Metal-Organic Frameworks (MOFs) gaining increasing interest in heterogeneous catalysis owing to their advantageous properties such as superior porosity, high surface area, ample catalytic sites. Their can be tailored by varying the metal ions or clusters (nodes) and organic linkers. Magnetically active nano core-shell MOF composites are also discovered for easy separation reuse of catalyst. catalysed multicomponent reactions (MCRs) satisfy several green chemistry principles thus considered a sturdy step towards sustainable chemical synthesis. In this article, synthesis biologically potent pyran scaffolds through MCR approaches have been reviewed. Preparation catalyst, its performance synthesis, reusability has discussed with reaction each example.

Language: Английский

Citations

0