Nanomedicine Combats Drug Resistance in Lung Cancer

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(3)

Published: Nov. 16, 2023

Lung cancer is the second most prevalent and leading cause of cancer-related death worldwide. Surgery, chemotherapy, molecular targeted therapy, immunotherapy, radiotherapy are currently available as treatment methods. However, drug resistance a significant factor in failure lung treatments. Novel therapeutics have been exploited to address complicated mechanisms advancement nanomedicine extremely promising terms overcoming resistance. Nanomedicine equipped with multifunctional tunable physiochemical properties alignment tumor genetic profiles can achieve precise, safe, effective while minimizing or eradicating cancer. Here, this work reviews discovered for radiotherapy, outlines novel strategies development against This focuses on engineering design, customized delivery, current challenges, clinical translation application resistant

Language: Английский

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Design, characterization and applications of nanocolloidal hydrogels

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(15), P. 5317 - 5339

Published: Jan. 1, 2023

This review covers the mechanisms of formation, properties, characterization, and a broad range applications nanocolloidal gels that are an evolving class soft matter materials in which nanoparticles act as building block network.

Language: Английский

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Nanomaterials-incorporated hydrogels for 3D bioprinting technology

Nano Convergence, Journal Year: 2023, Volume and Issue: 10(1)

Published: Nov. 15, 2023

Abstract In the field of tissue engineering and regenerative medicine, various hydrogels derived from extracellular matrix have been utilized for creating engineered tissues implantable scaffolds. While these hold immense promise in healthcare landscape, conventional bioinks based on ECM face several challenges, particularly terms lacking necessary mechanical properties required 3D bioprinting process. To address limitations, researchers are actively exploring novel nanomaterial-reinforced both functional aspects. this review, we focused discussing recent advancements fabrication monitoring systems using nanobioinks nanomaterials via technology. We highlighted synergistic benefits combining numerous into imposing geometrical effects by Furthermore, also elaborated critical issues remaining at moment, such as inhomogeneous dispersion consequent technical practical issues, complex structures with nanomaterials. Finally, plausible outlooks facilitating use biofabrication advancing function tissues.

Language: Английский

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A multimaterial 3D printing-assisted micropatterning for heat dissipation applications

Advanced Composites and Hybrid Materials, Journal Year: 2023, Volume and Issue: 6(3)

Published: May 3, 2023

Language: Английский

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Dispersion strategies of nanomaterials in polymeric inks for efficient 3D printing of soft and smart 3D structures: A systematic review

Advances in Colloid and Interface Science, Journal Year: 2024, Volume and Issue: 333, P. 103285 - 103285

Published: Aug. 26, 2024

Nanoscience-often summarized as "the future is tiny"-highlights the work of researchers advancing nanotechnology through incremental innovations. The design and innovation new nanomaterials are vital for development next-generation three-dimensional (3D) printed structures characterized by low cost, high speed, versatile capabilities, delivering exceptional performance in advanced applications. integration nanofillers into polymeric-based inks 3D printing heralds a era additive manufacturing, allowing creation custom-designed objects with enhanced multifunctionality. To optimize use printing, effective disaggregation techniques strong interfacial adhesion between polymer matrices essential. This review provides an overview application various types used focusing on their functionalization principles, dispersion strategies, colloidal stability, well methodologies aligning within framework. It discusses dispersive methods, synergistic dispersion, in-situ growth, which have yielded smart 3D-printed unique functionality specific also focuses nanomaterial alignment detailing methods that enhance selective deposition orientation established customized techniques. By emphasizing we explore impact composites highlight potential applications benefit from ordered nanoparticles. Through these continuing efforts, this shows class crucial to developing next generation architectures abilities performance.

Language: Английский

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Meta-materials of Re-entrant Negative Poisson’s Ratio Structures Made from Fiber-Reinforced Plastics: A Short Review

Fibers and Polymers, Journal Year: 2024, Volume and Issue: 25(2), P. 395 - 406

Published: Jan. 9, 2024

Language: Английский

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Thermally Conductive and Electrically Insulating Polymer-Based Composites Heat Sinks Fabricated by Fusion Deposition Modeling

Polymers, Journal Year: 2024, Volume and Issue: 16(3), P. 432 - 432

Published: Feb. 4, 2024

This study explores the potential of novel boron nitride (BN) microplatelet composites with combined thermal conduction and electrical insulation properties. These are manufactured through Fusion Deposition Modeling (FDM), their application for management in electronic devices is demonstrated. The primary focus this work is, therefore, investigation thermoplastic composite properties to show 3D printing lightweight polymeric heat sinks remarkable performance. By comparing various microfillers, including BN MgO particles, effects on material alignment within polymer matrix during filament fabrication FDM processing analyzed. characterization includes evaluation morphology, conductivity, mechanical Particularly, a 32 wt% microplatelets shows an in-plane conductivity 1.97 W m-1 K-1, offering excellent printability. To assess practical applications, pin fin using these designed printed. Their performance evaluated via thermography under different heating conditions. findings very promising efficient cost-effective devices, which can be obtained extrusion-based Additive Manufacturing (AM), such as FDM, exploited enhanced solutions devices.

Language: Английский

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Micro-arranged ZnO particles and conductive fillers in PCL composites for enhanced piezoelectric and dielectric properties in bone tissue engineering applications

Materials & Design, Journal Year: 2025, Volume and Issue: unknown, P. 113672 - 113672

Published: Jan. 1, 2025

Language: Английский

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Orientation of macro/microscopic structures in anisotropic materials through 3D printing: Rheological behavior, processing, and properties

Composites Part A Applied Science and Manufacturing, Journal Year: 2025, Volume and Issue: 192, P. 108767 - 108767

Published: Feb. 2, 2025

Language: Английский

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Self‐Regulative Direct Ink Writing of Frontally Polymerizing Thermoset Polymers

Advanced Materials Technologies, Journal Year: 2022, Volume and Issue: 7(9)

Published: April 27, 2022

Abstract The ability to manufacture highly intricate designs is one of the key advantages 3D printing. Achieving high dimensional accuracy requires precise, often time‐consuming calibration process parameters. Computerized feedback control systems for printing enable sensing and real‐time adaptation optimization these parameters at every stage print, but multiple challenges remain with sensor embedment measurement accuracy. In contrast active approaches, here, authors harness frontal polymerization (FP) rapidly cure extruded filament in tandem process. A temperature gradient present along filament, which dependent on parameters, can impose over this exothermic reaction. Experiments theory reveal a self‐regulative mechanism between kinetics that allows speed autonomously match print speed. This adapts changes environmental conditions produce complex, high‐fidelity structures freestanding architectures spanning up 100 mm, greatly expanding capabilities direct ink writing (DIW).

Language: Английский

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