Catalysts,
Journal Year:
2023,
Volume and Issue:
13(6), P. 985 - 985
Published: June 8, 2023
Perovskite
barium
titanate
(BaTiO3)
has
received
a
lot
of
interest
due
to
its
extraordinary
dielectric
and
ferroelectric
properties,
along
with
moderate
biocompatibility.
Here,
we
investigated
how
Zn
doping
tuned
the
physicochemical
characteristics,
photocatalytic
activity,
anticancer
potential
BaTiO3
nanoparticles
synthesized
from
banana
peel
extract.
XRD,
TEM,
SEM,
EDS,
XPS,
BET,
Raman,
PL
were
utilized
characterize
as-synthesized
pure
(1
3
mol%)-doped
nanoparticles.
All
samples
showed
evidence
tetragonal
phase,
XRD
patterns
Zn-doped
presence
peak.
The
particle
size
decreased
increasing
levels
without
morphological
changes.
After
doping,
intensity
decreased,
suggesting
lower
electron–hole
recombination
rate.
BET
analysis
found
that
surface
area
was
higher
than
BaTiO3.
Under
visible
irradiation,
activity
compared,
remarkable
85%
(3%)-doped
measured.
As
result,
are
recognized
as
excellent
photocatalysts
for
degrading
organic
pollutants.
According
cytotoxicity
data,
display
four-fold
greater
against
human
lung
carcinoma
(A549)
It
also
observed
kill
cancer
cells
by
intracellular
level
reactive
oxygen
species.
Furthermore,
compared
BaTiO3,
nanostructure
better
cytocompatibility
in
non-cancerous
fibroblasts
(IMR90).
have
reduced
size,
increased
area,
rate,
which
highly
beneficial
enhanced
activity.
Overall,
current
data
green-fabricated
Zn-BaTiO3
superior
effects
improved
biocompatibility
those
This
work
underlines
significance
utilizing
agricultural
waste
(e.g.,
fruit
peel)
fabrication
BaTiO3-based
nanostructures,
hold
great
promise
biomedical
environmental
applications.
The
skeleton
is
highly
innervated
by
numerous
nerve
fibers.
These
fibers,
in
addition
to
transmitting
information
within
the
bone
and
mediating
sensations,
play
a
crucial
role
regulating
tissue
formation
regeneration.
Traditional
engineering
(BTE)
often
fails
achieve
satisfactory
outcomes
when
dealing
with
large-scale
defects,
which
frequently
related
lack
of
effective
reconstruction
neurovascular
network.
In
recent
years,
increasing
research
has
revealed
critical
nerves
metabolism.
Nerve
fibers
regulate
cells
through
neurotransmitters,
neuropeptides,
peripheral
glial
cells.
Furthermore,
also
coordinate
vascular
immune
systems
jointly
construct
microenvironment
favorable
for
As
signaling
driver
formation,
neuroregulation
spans
entire
process
physiological
activities
from
embryonic
postmaturity
remodeling
repair.
However,
there
currently
comprehensive
summaries
these
regulatory
mechanisms.
Therefore,
this
review
sketches
out
function
during
Then,
we
elaborate
on
mechanisms
coupling
neuromodulation
immunity.
Finally,
discuss
several
novel
strategies
neuro-bone
(NBTE)
based
bone,
focusing
coordinated
regeneration
tissue.
Materials Today Bio,
Journal Year:
2025,
Volume and Issue:
31, P. 101553 - 101553
Published: Feb. 5, 2025
Wounds
infected
by
bacteria
pose
a
considerable
challenge
in
the
field
of
healthcare,
particularly
with
increasing
prevalence
antibiotic-resistant
pathogens.
Traditional
antibiotics
often
fail
to
achieve
effective
results
due
limited
penetration,
resistance
development,
and
inadequate
local
concentration
at
wound
sites.
These
limitations
necessitate
exploration
alternative
strategies
that
can
overcome
drawbacks
conventional
therapies.
Nanomaterials
have
emerged
as
promising
solution
for
tackling
bacterial
infections
facilitating
healing,
thanks
their
distinct
physicochemical
characteristics
multifunctional
capabilities.
This
review
highlights
latest
developments
nanomaterials
demonstrated
enhanced
antibacterial
efficacy
improved
healing
outcomes.
The
mechanisms
are
varied,
including
ion
release,
chemodynamic
therapy,
photothermal/photodynamic
electrostatic
interactions,
delivery
drugs,
which
not
only
combat
but
also
address
challenges
posed
biofilms
antibiotic
resistance.
Furthermore,
these
create
an
optimal
environment
tissue
regeneration,
promoting
faster
closure.
By
leveraging
unique
attributes
nanomaterials,
there
is
significant
opportunity
revolutionize
management
wounds
markedly
improve
patient
Journal of Functional Biomaterials,
Journal Year:
2025,
Volume and Issue:
16(4), P. 114 - 114
Published: March 24, 2025
Cancer
significantly
impacts
human
quality
of
life
and
expectancy,
with
an
estimated
20
million
new
cases
10
cancer-related
deaths
worldwide
every
year.
Standard
treatments
including
chemotherapy,
radiotherapy,
surgical
removal,
for
aggressive
cancers,
such
as
glioblastoma,
are
often
ineffective
in
late
stages.
Glioblastoma,
example,
is
known
its
poor
prognosis
post-diagnosis,
a
median
survival
time
approximately
15
months.
Novel
therapies
using
local
electric
fields
have
shown
anti-tumour
effects
glioblastoma
by
disrupting
mitotic
spindle
assembly
inhibiting
cell
growth.
However,
constant
application
poses
risks
like
patient
burns.
Wireless
stimulation
via
piezoelectric
nanomaterials
offers
safer
alternative,
requiring
ultrasound
activation
to
induce
therapeutic
effects,
altering
voltage-gated
ion
channel
conductance
depolarising
membrane
potentials.
This
review
highlights
the
mechanism,
drug
delivery,
activation,
current
technologies
cancer
therapy,
emphasising
need
further
research
address
limitations
biocompatibility
whole
systems.
The
goal
underscore
these
areas
inspire
avenues
overcome
barriers
developing
nanoparticle-based
therapies.
Small,
Journal Year:
2023,
Volume and Issue:
19(37)
Published: May 18, 2023
Next-generation
electronics
and
energy
technologies
can
now
be
developed
as
a
result
of
the
design,
discovery,
development
novel,
environmental
friendly
lead
(Pb)-free
ferroelectric
materials
with
improved
characteristics
performance.
However,
there
have
only
been
few
reports
such
complex
materials'
design
multi-phase
interfacial
chemistry,
which
facilitate
enhanced
properties
In
this
context,
herein,
novel
lead-free
piezoelectric
(1-x)Ba0.95
Ca0.05
Ti0.95
Zr0.05
O3
-(x)Ba0.95
Sn0.05
,
are
reported,
represented
(1-x)BCZT-(x)BCST,
demonstrated
excellent
harvesting
The
(1-x)BCZT-(x)BCST
synthesized
by
high-temperature
solid-state
ceramic
reaction
method
varying
x
in
full
range
(x
=
0.00-1.00).
In-depth
exploration
research
is
performed
on
structural,
dielectric,
ferroelectric,
electro-mechanical
ceramics.
formation
perovskite
structure
for
all
ceramics
without
presence
any
impurity
phases
confirmed
X-ray
diffraction
(XRD)
analyses,
also
reveals
that
Ca2+
Zr4+
Sn4+
well
dispersed
within
BaTiO3
lattice.
For
ceramics,
thorough
investigation
phase
phase-stability
using
XRD,
Rietveld
refinement,
Raman
spectroscopy,
high-resolution
transmission
electron
microscopy
(HRTEM),
temperature-dependent
dielectric
measurements
provide
conclusive
evidence
coexistence
orthorhombic
+
tetragonal
(Amm2
P4mm)
at
room
temperature.
steady
transition
Amm2
crystal
symmetry
to
P4mm
increasing
content
refinement
data
related
analyses.
temperatures,
rhombohedral-orthorhombic
(TR-O
),
orthorhombic-
(TO-T
tetragonal-cubic
(TC
gradually
shift
toward
lower
temperature
content.
significantly
observed,
including
relatively
high
constant
εr
≈
1900-3300
(near
temperature),
8800-12
900
Curie
loss,
tan
δ
0.01-0.02,
remanent
polarization
Pr
9.4-14
µC
cm-2
coercive
electric
field
Ec
2.5-3.6
kV
cm-1
.
Further,
field-induced
strain
S
0.12-0.175%,
charge
coefficient
d33
296-360
pC
N-1
converse
(d33∗)ave${(
{d_{33}^*}
)}_{{\rm{ave}}}$
240-340
pm
V-1
planar
electromechanical
coupling
kp
0.34-0.45,
electrostrictive
(Q33
)avg
0.026-0.038
m4
C-2
attained.
Output
performance
respect
mechanical
demonstrates
(0.6)BCZT-(0.4)BCST
composition
0.4)
displays
better
efficiency
generating
electrical
and,
thus,
samples
suitable
applications.
results
analyses
point
outcome
potentially
strong
contender
family
Pb-free
future
device
technologies.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(19), P. 2797 - 2797
Published: Oct. 2, 2024
Bone
repair
and
regeneration
require
physiological
cues,
including
mechanical,
electrical,
biochemical
activity.
Many
biomaterials
have
been
investigated
as
bioactive
scaffolds
with
excellent
electrical
properties.
Amongst
biomaterials,
piezoelectric
materials
(PMs)
are
gaining
attention
in
biomedicine,
power
harvesting,
biomedical
devices,
structural
health
monitoring.
PMs
unique
properties,
such
the
ability
to
affect
movements
deliver
stimuli
damaged
bone
or
cells
without
an
external
source.
The
crucial
property
is
its
piezoelectricity.
Bones
can
generate
charges
potential
response
mechanical
stimuli,
they
influence
growth
regeneration.
Piezoelectric
respond
human
microenvironment
important
factor
repair.
This
manuscript
overview
of
fundamentals
generating
effect
their
on
paper
focuses
state
art
materials,
polymers,
ceramics,
composites,
application
tissue
engineering.
We
present
information
from
point
view
highlight
promising
upcoming
approaches
new
generations
materials.
Bioengineering,
Journal Year:
2024,
Volume and Issue:
11(2), P. 193 - 193
Published: Feb. 17, 2024
Bone
defects
are
a
significant
health
problem
worldwide.
Novel
treatment
approaches
in
the
tissue
engineering
field
rely
on
use
of
biomaterial
scaffolds
to
stimulate
and
guide
regeneration
damaged
that
cannot
repair
or
regrow
spontaneously.
This
work
aimed
at
developing
characterizing
new
piezoelectric
provide
electric
bio-signals
naturally
present
bone
vascular
tissues.
Mixing
extrusion
were
used
obtain
nanocomposites
made
polyhydroxybutyrate
(PHB)
as
matrix
barium
titanate
(BaTiO3)
nanoparticles
filler,
BaTiO3/PHB
compositions
5/95,
10/90,
15/85
20/80
(w/w%).
The
morphological,
thermal,
mechanical
properties
studied.
Scanning
electron
microscopy
analysis
showed
good
nanoparticle
dispersion
within
polymer
matrix.
Considerable
increases
Young’s
modulus,
compressive
strength
coefficient
d31
observed
with
increasing
BaTiO3
content,
=
37
pm/V
(w/w%)
BaTiO3/PHB.
3D
printing
was
produce
porous
cubic-shaped
using
90°
lay-down
pattern,
pore
size
ranging
0.60–0.77
mm
stability.
Biodegradation
tests
conducted
for
8
weeks
saline
solution
°C
low
mass
loss
(∼4%)
printed
scaffolds.
results
obtained
terms
piezoelectric,
chemical
nanocomposite
promising
strategy
vascularized
engineering.
