Environmental Science Nano,
Journal Year:
2024,
Volume and Issue:
11(9), P. 3744 - 3760
Published: Jan. 1, 2024
Methanol
probe
chemisorption
quantifies
the
number
of
reactive
sites
at
surface
engineered
nanomaterials,
enabling
normalization
per
site
in
reactivity
and
toxicity
tests,
rather
than
mass
or
physical
area.
Subsequent
temperature-programmed
reaction
(TPSR)
chemisorbed
methanol
identifies
nature
(acidic,
basic,
redox
combination
thereof)
their
reactivity.
Complementary
to
assay,
a
dithiothreitol
(DTT)
oxidation
is
used
evaluate
capacity.
These
acellular
approaches
quantify
number,
nature,
constitute
new
approach
methodology
(NAM)
for
site-specific
classification
nanomaterials.
As
proof
concept,
CuO,
CeO2,
ZnO,
Fe3O4,
CuFe2O4,
Co3O4
two
TiO2
nanomaterials
were
probed.
A
harmonized
descriptor
ENMs
was
obtained:
DTT
rate
site,
oxidative
turnover
frequency
(OxTOF).
CuO
CuFe2O4
exhibit
largest
density
possess
highest
oxidizing
ability
series,
as
estimated
by
reaction,
followed
CeO2
NM-211
then
titania
(DT-51
NM-101)
Fe3O4.
depletion
ZnO
NM-110
associated
with
dissolved
zinc
ions
particles;
however,
basic
characteristics
particles
evidenced
TPSR.
assays
allow
ranking
eight
into
three
categories
statistically
different
potentials:
are
most
reactive;
ceria
exhibits
moderate
reactivity;
iron
oxide
titanias
low
potential.
Advanced Materials,
Journal Year:
2024,
Volume and Issue:
36(18)
Published: Jan. 19, 2024
Abstract
Machine
learning
holds
significant
research
potential
in
the
field
of
nanotechnology,
enabling
nanomaterial
structure
and
property
predictions,
facilitating
materials
design
discovery,
reducing
need
for
time‐consuming
labor‐intensive
experiments
simulations.
In
contrast
to
their
achiral
counterparts,
application
machine
chiral
nanomaterials
is
still
its
infancy,
with
a
limited
number
publications
date.
This
despite
great
advance
development
new
sustainable
high
values
optical
activity,
circularly
polarized
luminescence,
enantioselectivity,
as
well
analysis
structural
chirality
by
electron
microscopy.
this
review,
an
methods
used
studying
provided,
subsequently
offering
guidance
on
adapting
extending
work
nanomaterials.
An
overview
within
framework
synthesis–structure–property–application
relationships
presented
insights
how
leverage
study
these
highly
complex
are
provided.
Some
key
recent
reviewed
discussed
Finally,
review
captures
achievements,
ongoing
challenges,
prospective
outlook
very
important
field.
