Therapeutic Potential of Insect Defensin DLP4 Against Staphylococcus hyicus-Infected Piglet Exudative Epidermitis DOI Creative Commons

Xuanxuan Ma,

Zhimin Dong, Ruoyu Mao

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(11), P. 1350 - 1350

Published: Oct. 22, 2024

: The emergence of resistance to

Language: Английский

Phosphonium Cationic Borneol Stereochemical Membrane Breaking Arrow: High Antibacterial and Antibiofilm Activity DOI
Xiangbin Sun, Yuanyuan Xie,

Xiaobing Ma

et al.

Macromolecules, Journal Year: 2025, Volume and Issue: unknown

Published: April 4, 2025

Language: Английский

Citations

0

Reshaping bacterial microenvironments: Hybrid biomimetic membrane-coated copper nanosystems combat bacterial biofilm infections by inhibiting bacterial quorum sensing systems DOI
Liqiang Wang,

Qianyu Cai,

Yonglan Yang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162088 - 162088

Published: April 1, 2025

Language: Английский

Citations

0

Clinical translation and envisioned impact of nanotech for infection control: Economy, government policy and public awareness DOI
Xiaohan Ma, Alessandro Poma

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 299 - 392

Published: Aug. 30, 2024

Language: Английский

Citations

2

Nanocatalytic Medicine Enabled Next-Generation Therapeutics for Bacterial Infections DOI Creative Commons
Min Ge, Feng Jiang, Han Lin

et al.

Materials Today Bio, Journal Year: 2024, Volume and Issue: 29, P. 101255 - 101255

Published: Sept. 17, 2024

Language: Английский

Citations

2

“Stop, Little Pot” as the Motto of Suppressive Management of Various Microbial Consortia DOI Creative Commons
Елена Ефременко, Nikolay Stepanov,

Olga Senko

et al.

Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1650 - 1650

Published: Aug. 12, 2024

The unresolved challenges in the development of highly efficient, stable and controlled synthetic microbial consortia, as well use natural are very attractive for science technology. However, consortia management should be done with knowledge how not only to accelerate but also stop action such "little pots". Moreover, there a lot activity which suppressively controlled. processes, catalyzed by various microorganisms being complex slowed down or completely cancelled, typical environment (biocorrosion, landfill gas accumulation, biodegradation building materials, water sources deterioration etc.), industry (food biotechnological production), medical practice (vaginitis, cystitis, intestinal dysbiosis, etc.). search ways suppress functioning heterogeneous each these areas is relevant. purpose this review summarize general trends studies regarding targets new means influence used. analysis features applied approaches solving main problem confirms possibility obtaining combined effect, selective on individual components consortia. Of particular interest role viruses suppressing different compositions.

Language: Английский

Citations

1

How Nanoparticles Help in Combating Chronic Wound Biofilms Infection? DOI Creative Commons

Gang Jing,

Chen Hu,

Keyi Fang

et al.

International Journal of Nanomedicine, Journal Year: 2024, Volume and Issue: Volume 19, P. 11883 - 11921

Published: Nov. 1, 2024

Chronic wound infection has become a global health problem, with bacterial biofilms, which are difficult to penetrate using traditional antibiotics, considered the primary cause of recurrent and delayed healing in chronic wounds. In recent years, outstanding performance nanomaterials controlling biofilm infections been widely acknowledged, these materials regarded as highly promising for management. The formation structure biofilms undergo complex dynamic changes. Therefore, deep understanding underlying causes repeated specific antibacterial mechanisms at different stages is crucial effective "chronic management". This review first reveals relationship between chronicity, infections. Secondly, it focuses on four formation: (1) adhesion stage, (2) aggregation promotion (3) maturation (4) regeneration dissemination stage. It also comprehensively summarizes nanomaterials. study analyzes essential factors affecting control by nanoparticles from various perspectives, such material itself, local environment, systemic host response. Finally, limitations potential future trends current research discussed. summary, represent strategy combating infections, this provides new insights alternative adjuvant therapies managing

Language: Английский

Citations

1

Recent advances in the bench-to-bedside translation of cancer nanomedicines DOI Creative Commons
Yang Liu, Yinchao Zhang, Huikai Li

et al.

Acta Pharmaceutica Sinica B, Journal Year: 2024, Volume and Issue: 15(1), P. 97 - 122

Published: Dec. 14, 2024

Cancer remains a complex and challenging medical problem, driving extensive research efforts. Despite significant progress in understanding its genetic molecular aspects, the quest for effective treatments continues. Nanomedicines have shown great potential revolutionizing cancer treatment by offering targeted controlled drug delivery, reducing side effects, improving patient outcomes. Accordingly, nanomedicines been focus of development clinical translation. As September 2024, search on ClinicalTrials.gov website using term "nanoparticles" revealed numerous ongoing planned trials. Motivated recent advances field, this review explores current frontier nanomedicine. supported chemotherapy, phototherapy sonodynamic therapy, nucleic acid immunotherapy. However, translating into practice has challenged interactions between nanoparticles biological systems, variable permeability retention tumors, safety concerns, difficulty achieving issues with scaling up manufacturing. Perspectives addressing these challenges are offered. Future opportunities nanomedicines, including modifying tumor microenvironment, integrating artificial intelligence big data, targeting new areas, also discussed. This underscores to revolutionize from standpoint.

Language: Английский

Citations

1

Therapeutic Potential of Insect Defensin DLP4 Against Staphylococcus hyicus-Infected Piglet Exudative Epidermitis DOI Creative Commons

Xuanxuan Ma,

Zhimin Dong, Ruoyu Mao

et al.

Pharmaceutics, Journal Year: 2024, Volume and Issue: 16(11), P. 1350 - 1350

Published: Oct. 22, 2024

: The emergence of resistance to

Language: Английский

Citations

0