Dynamic Interface-Assisted Rapid Self-Assembly of DNA Origami-Framed Anisotropic Nanoparticles DOI Creative Commons

Yanfei Qu,

Fengyun Shen,

Hongzhen Peng

et al.

JACS Au, Journal Year: 2024, Volume and Issue: 4(3), P. 903 - 907

Published: March 8, 2024

The ordered arrangement of nanoparticles can generate unique physicochemical properties, rendering it a pivotal direction in the field nanotechnology. DNA-based chemical encoding has emerged as an unparalleled strategy for orchestrating precise and controlled nanoparticle assemblies. Nonetheless, is often time-consuming limited assembly efficiency. In this study, we developed rapid DNA origami-framed assisted by dynamic interfaces. By assembling Au (AuNPs) onto origami with different sticky ends various directions, endowed them anisotropic specific affinities. After AuNPs supported lipid bilayers freely diffusing single-stranded via hybridization, found that could form larger assemblies than those 3D solution within equivalent time frames. Furthermore, also achieved liposome employing aforementioned strategy. Our work provides novel avenue efficient across two-dimensional interfaces, which expected to promote application sensor biomimetic system construction.

Language: Английский

Dynamic Interface-Assisted Rapid Self-Assembly of DNA Origami-Framed Anisotropic Nanoparticles DOI Creative Commons

Yanfei Qu,

Fengyun Shen,

Hongzhen Peng

et al.

JACS Au, Journal Year: 2024, Volume and Issue: 4(3), P. 903 - 907

Published: March 8, 2024

The ordered arrangement of nanoparticles can generate unique physicochemical properties, rendering it a pivotal direction in the field nanotechnology. DNA-based chemical encoding has emerged as an unparalleled strategy for orchestrating precise and controlled nanoparticle assemblies. Nonetheless, is often time-consuming limited assembly efficiency. In this study, we developed rapid DNA origami-framed assisted by dynamic interfaces. By assembling Au (AuNPs) onto origami with different sticky ends various directions, endowed them anisotropic specific affinities. After AuNPs supported lipid bilayers freely diffusing single-stranded via hybridization, found that could form larger assemblies than those 3D solution within equivalent time frames. Furthermore, also achieved liposome employing aforementioned strategy. Our work provides novel avenue efficient across two-dimensional interfaces, which expected to promote application sensor biomimetic system construction.

Language: Английский

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