Electrochemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 368 - 403
Published: Nov. 27, 2024
Electrochemistry,
a
vast
scientific
discipline,
finds
application
across
numerous
fields
and
has
the
potential
to
surpass
traditional
analytical
methods.
Surprisingly,
one
area
that
may
not
immediately
come
mind
for
electrochemical
is
forensic
science.
Forensic
science
encompasses
various
subfields,
including
detection
of
illicit
drugs,
crime
scene
investigation,
DNA
evidence
analysis.
This
chapter
delves
into
fascinating
world
science,
where
sensor
technologies
serve
as
invaluable
tools
in
unraveling
mysteries.
From
analyzing
detecting
trace
amounts
substances,
these
sensors
offer
unique
perspective,
akin
“electrochemical
eyes,”
enabling
investigators
uncover
crucial
clues
piece
together
intricate
puzzles.
Through
case
studies
innovative
applications,
this
highlights
pivotal
role
investigations,
shedding
light
on
hidden
truths
bringing
justice
forefront.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 16, 2025
Abstract
Wearable
sensors
are
transforming
healthcare
by
facilitating
rapid,
non‐invasive,
on‐body
biochemical
analysis
in
biofluids
such
as
sweat,
tears,
saliva,
and
blood,
providing
real‐time
insights
into
health
conditions.
Despite
extensive
academic
industrial
efforts
developing
wearable
devices,
very
few
tailored
to
meet
women's
needs.
None
specifically
designed
for
measurements
human
breast
milk.
Beyond
being
the
optimal
source
of
infant
nutrition,
milk
serves
a
rich
biofluid
containing
potential
biomarkers
reflecting
mother's
well.
Analyzing
composition
offers
valuable
information
infant,
mother.
This
work
pioneers
sensor
embedded
lactation
pad
sampling
continuous
glucose
levels
Lactation
pads
worn
most
lactating
individuals
absorb
leakage
during
day,
keep
cloth
dry.
In
this
work,
integrating
microfluidic
channels
electrochemical
pad,
becomes
part
an
existing
daily
routine
mother,
posing
no
additional
burden
analysis.
The
developed
using
laser‐induced
carbonization
polyimide
thin
films,
allowing
development
flexible,
low‐cost,
high‐surface
area
electrodes.
Glucose
sensing
is
done
via
enzymatic
membrane
composed
oxidase,
glutaraldehyde,
bovine
serum
albumin,
Nafion
achieve
enhanced
enzyme
protection
extended
biosensor
shelf
life
operation
Notably,
device
demonstrates
high
accuracy
(96.8
104.1%)
measurement
whole
undiluted
milk,
collected
1st,
6th,
12th
months
postpartum.
innovative
smart
empowers
mothers
track
their
babies'
intake
potentially
identify
early
signs
concerns.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 24, 2025
Abstract
Muscle
on
a
Chip
devices
are
valuable
research
tools
for
interrogating
the
structure
and
physiology
of
engineered
heart,
skeletal,
or
smooth
muscle
tissue
constructs
from
molecular
to
multi‐cellular
level.
However,
many
existing
rely
functional
assays
with
limited
throughput,
such
as
optical
microscopy,
measure
contractility.
Although
electrical
components
have
been
integrated
automate
recordings
in
advanced
devices,
their
fabrication
typically
requires
specialized
equipment
found
cleanroom
facilities.
In
this
work,
miniature
strain
gauges
record
contractions
skeletal
bundles
using
only
benchtop
equipment.
A
commercial
CO
2
laser
is
employed
generate
patterns
laser‐induced
graphene
(LIG)
polyimide
(PI)
films.
LIG
then
transferred
PI
thin
polydimethylsiloxane
(PDMS)
films
make
conductive
intrinsically
flexible
stretchable
layers
that
demonstrate
long‐term
stability
under
repeated
cycles
stretch.
Engineered
anchored
LIG‐PDMS
contraction
sensed
response
stimulation,
which
delivered
by
LIG‐PI
stimulation
electrodes
also
into
device.
Collectively,
these
results
an
attractive
material
rapidly
inexpensively
integrating
situ
sensing
devices.
ACS Applied Bio Materials,
Journal Year:
2024,
Volume and Issue:
7(6), P. 3865 - 3876
Published: May 23, 2024
The
study
presents
a
first
electrochemical
method
for
the
determination
of
immunomodulator
drug
Baricitinib
(BARI),
crucial
in
managing
COVID-19
patients
requiring
oxygen
support.
A
unique
electrode
was
developed
by
modifying
graphite
carbon
nickel
nanoparticles
(NiNPs)
with
functionalized
multiwalled
nanotubes
(f.MWCNTs),
resulting
nanohybrids
tailored
highly
sensitive
BARI
detection.
Comparative
analysis
revealed
superior
electrocatalytic
performance
nanohybrid-modified
over
unmodified
counterparts
and
other
modifications,
attributed
to
synergistic
interactions
between
f.MWCNTs
nanoparticles.
Under
optimized
conditions,
sensors
exhibited
linear
detection
within
concentration
range
from
4.00
×
10–8
5.56
10–5
M,
remarkably
low
limit
9.65
10–9
M.
Notably,
modified
displayed
minimal
interference
common
substances
demonstrated
high
precision
detecting
plasma
medicinal
formulations,
underscoring
its
clinical
relevance
potential
impact
on
treatment
strategies.
Lab on a Chip,
Journal Year:
2024,
Volume and Issue:
24(18), P. 4306 - 4320
Published: Jan. 1, 2024
Saliva
has
emerged
as
a
primary
biofluid
for
non-invasive
disease
diagnostics.
collection
involves
using
kits
where
individuals
stimulate
saliva
production
ACS Materials Letters,
Journal Year:
2024,
Volume and Issue:
6(9), P. 4158 - 4167
Published: Aug. 15, 2024
This
work
develops
the
first
laser-induced
graphene
(LIG)-based
electrochemical
sensor
with
a
superhydrophobic
fluorous
membrane
for
flexible
acetylcholine
(ACh)
sensor.
ACh
regulates
several
physiological
functions,
including
synaptic
transmission
and
glandular
secretion.
The
sensing
is
doped
fluorophilic
cation-exchanger
that
can
selectively
measure
based
on
inherent
selectivity
of
phase
hydrophobic
ions,
such
as
ACh.
fluorous-phase
improves
over
Na
Journal of The Electrochemical Society,
Journal Year:
2024,
Volume and Issue:
171(5), P. 057511 - 057511
Published: May 1, 2024
Velpatasvir,
an
antiviral
agent
co-formulated
with
sofosbuvir
used
to
treat
hepatitis
C,
has
recently
demonstrated
beneficial
therapeutic
effects
against
COVID-19.
Therefore,
drug
monitoring
of
velpatasvir
is
essential
achieve
the
desired
clinical
outcomes.
An
electrochemical
sensor
modified
synthesized
copper
oxide
nanoparticles
on
surface
graphene
(CuO/GO-NPs)
was
fabricated
for
analysis
first
time.
Characterization
carried
out
using
Fourier-transform
infrared
spectroscopy,
X-ray
diffraction,
and
scanning
electron
microscopy
energy-dispersive
spectroscopy.
The
voltammetric
determinations
were
conducted
differential
pulse
cyclic
voltammetry,
where
electrode
exhibited
better
sensitivity
than
unmodified
one.
method
validated
according
International
Council
Harmonisation
(ICH)
guidelines,
exhibiting
linearity
within
a
range
1.0
×
10
−7
–
−5
M,
covering
velpatasvir’s
maximum
plasma
concentration
(Cmax),
quantification
limit
2.89
M
detection
9.03
−8
M.
developed
successfully
applied
spiked
human
at
Cmax
level.
method’s
greenness
assessed
Analytical
Eco-scale
Green
analytical
procedure
index
tools.
This
holds
promise
as
green
simple
approach
implemented
in
future
studies.