One‐Pot and Gram‐Scale Synthesis of Fe‐Based Nanozymes with Tunable O2 Activation Pathway and Specificity Between Associated Enzymatic Reactions DOI
Yuwei Qiu, Tianqi Cheng, Bo Yuan

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 15, 2024

Abstract Nanozymes have recently gained attention for their low cost and high stability. However, unlike natural enzymes, they often exhibit multiple enzyme‐like activities, complicating use in selective bioassays. Since H 2 O are common substrates these reactions, controlling activation—and thus reaction specificity—is crucial. Recent advances tuning the chemical state of cerium enabled control over activation pathways tunable peroxidase/haloperoxidase‐like activities. In contrast, on an element oxidase/laccase nanozymes impact its activities remains unexplored. Herein, a facile one‐pot method is presented gram‐scale synthesis Fe‐based with compositions Fe 3 4 C by adjusting preparation temperatures. The ‐containing samples superior laccase‐like activity, while C‐containing counterparts demonstrate better oxidase‐like activity. This divergent behavior linked to surface species: abundant reactive 2+ promotes activity via 3+ ‐superoxo formation, whereas metallic facilitates OH radical generation Controlled improved sensitivity corresponding biomolecule detection, which should inform design enhanced specificity.

Language: Английский

High-Efficiency Dual-Site Biomimetic Catalyst for Lignin Depolymerization DOI

Wenzhi Jiang,

Qifeng Li,

Meifang Cao

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 2595 - 2606

Published: Jan. 28, 2025

Language: Английский

Citations

0
Cobalt‐Silicon Coordination‐Induced Nonradical Activation of Peroxymonosulfate for Enhancing the Degradation of Organic Pollutants in Real Wastewater DOI Open Access
Shizong Wang, Jianlong Wang

Small, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 16, 2025

Abstract Nonradical‐driven degradation pathways have emerged as a promising solution for the removal of emerging organic pollutants in complex water matrices. How to construct nonradical systems remains challenge. In this study, novel silicon carbide (SiC)‐supported cobalt single‐atom catalyst (Co/SiC) is developed induce nonradicals activation peroxymonosulfate toward sulfamethoxazole (SMX). The normalized rate SMX reaches 16.425 L·min −1 ·g ·m m , significantly outperforming most reported catalysts. Surface‐bound reactive species dominate process, followed by high‐valent oxo. Experimental and characterization results demonstrate that unique Co‐Si coordination structure facilitated electron transfer, lowered energy barrier formation surface‐bound species, thereby exhibiting superior resistance inorganic ions. seven‐day continuous column experiment, SMX, atrazine, bisphenol A are completely removed from actual secondary effluent, confirming stability effectiveness real wastewater systems. Moreover, acute toxicity treated effluent almost disappears. These highlight potential driving transfer generation nonradicals, offering approach addressing challenges wastewater.

Language: Английский

Citations

0
Biomimetically Engineering Valency in Copper Aerogel Toward Efficient Laccase‐Mimicking Nanozyme DOI

Lijun Mao,

Jianqi Ye,

Wenhua Bi

et al.

Small, Journal Year: 2025, Volume and Issue: unknown

Published: April 8, 2025

Abstract Developing nanozymes with high intrinsic activity to bridge the gap natural enzymes has received unremitting attention. In this study, inspired by copper active center for laccase and multivalent characteristic of Cu, valence state Cu‐based aerogel is modulated via adjusting reductant usage mimicking laccase. The laccase‐mimicking well‐tailored manipulation, theoretical calculations unveil mechanism that Cu 0 I species enhance substrate adsorption capability II are paramount lowering activation barrier synergistically. Heterogeneous metals further incorporated promote valency‐conversion biomimetic electron transfer, conferring constructed CuPt 7.5% nanozyme an ultralow detectable limit 1 n m phenolic pollutants. This work highlights multivalence on provides insights into underlying catalytic mechanism, shedding light rational design high‐performance practical application.

Language: Английский

Citations

0
Copper Single‐Atom Nanozyme Mimicking Galactose Oxidase with Superior Catalytic Activity and Selectivity DOI
Eslam M. Hamed, Limo He,

Varun Rai

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 9, 2024

Abstract Due to the low stability and high cost of some natural enzymes, nanozymes have been developed as enzyme‐imitating nanomaterials. Single‐atom are a class with metal centers that mimic structure metal‐based enzymes. Herein, Cu‐N‐C single‐atom nanozyme (SAN) is synthesized excellent peroxidase‐ enhanced oxidase‐like activities action galactose oxidase. Cu‐SAN demonstrates stereospecific activity akin oxidase by oxidizing D‐galactose primary alcohol but not L‐Galactose or other carbohydrates. The SAN can catalyze oxidation in presence oxygen, producing hydrogen peroxide sub‐product. produced then oxidizes 3,3′,5,5′‐tetramethylbenzidine catalyzed SAN, yielding typical blue product. relationship between absorbance concentration linear 1–60 µ m range detection limit 0.23 . This strategy be utilized diagnosis galactosemia disorder dairy commercial products. DFT calculations clarify Cu sites POD‐like reaction explain selectivity toward

Language: Английский

Citations

3
Deciphering of laccase-like activity ruthenium single-atom nanozyme for identification/quantification and remediation of phenolic pollutants DOI
Rui Wang, Xiaowei Ma, Eslam M. Hamed

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 426, P. 137112 - 137112

Published: Dec. 10, 2024

Language: Английский

Citations

1
One‐Pot and Gram‐Scale Synthesis of Fe‐Based Nanozymes with Tunable O2 Activation Pathway and Specificity Between Associated Enzymatic Reactions DOI
Yuwei Qiu, Tianqi Cheng, Bo Yuan

et al.

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 15, 2024

Abstract Nanozymes have recently gained attention for their low cost and high stability. However, unlike natural enzymes, they often exhibit multiple enzyme‐like activities, complicating use in selective bioassays. Since H 2 O are common substrates these reactions, controlling activation—and thus reaction specificity—is crucial. Recent advances tuning the chemical state of cerium enabled control over activation pathways tunable peroxidase/haloperoxidase‐like activities. In contrast, on an element oxidase/laccase nanozymes impact its activities remains unexplored. Herein, a facile one‐pot method is presented gram‐scale synthesis Fe‐based with compositions Fe 3 4 C by adjusting preparation temperatures. The ‐containing samples superior laccase‐like activity, while C‐containing counterparts demonstrate better oxidase‐like activity. This divergent behavior linked to surface species: abundant reactive 2+ promotes activity via 3+ ‐superoxo formation, whereas metallic facilitates OH radical generation Controlled improved sensitivity corresponding biomolecule detection, which should inform design enhanced specificity.

Language: Английский

Citations

0