Assessment of multiple hemorheological properties in microfluidic environment DOI
Yang Jun Kang

Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(12)

Published: Dec. 1, 2024

Measuring and monitoring hemorheological properties provide valuable insights into diseases. To effectively detect impaired blood, it is necessary to quantify the multiple properties. However, most of previous methods only single blood property. They require bulky expensive syringe pumps for precise on–off control. In this study, resolve several issues, a novel method measuring (fluidic resistance, viscosity, time constant, compliance coefficient, red cell [RBC] aggregation index, RBC sedimentation index) proposed by analyzing images in microfluidic channels, where transient flow induced portable air-compression pump. A device consists an inlet, test chamber joined main channel, reservoir. The outlet connected air damper, which contributes stopping promptly. fluid circuit model channels constructed estimating rate pressure channel. First, used obtain rheological glycerin solution (30%). normalized difference between reference value less than 4%. Subsequently, adopted differences medium (1× phosphate-buffered saline, dextran solution: 20 mg/ml) hematocrit (30%–60%). All exhibit substantial with respect medium. yields comparable results when compared methods. conclusion, can measure channels.

Language: Английский

Particle manipulation under X-force fields DOI
Chun‐Dong Xue,

Yifan Yin,

Xiaoyu Xu

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

This review highlights recent technological advances for progress in particle manipulation under X-force fields, and forecasts the trajectory of future developments.

Language: Английский

Citations

0
Multi-Vortex Regulation in a Simple Semicircular Microchannel with Ordered Micro-Obstacles for High-Throughput Buffer Exchange DOI
Shaofei Shen, Furong Zhang, Haodong Li

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Microfluidics is an emerging technology for buffer exchange in bioprocessing applications. However, achieving with simplicity of operation and high throughput a straightforward channel design remains challenge. This study presents novel semicircular microchannel that allows the deterministic regulation helical Dean vortices through geometric confinement. By incorporating micro-obstacles into microchannels large dimensions (900 μm wide 100 high), we observe substantial enhancement secondary flows, leading to unique fluid distribution across range flow rates. enables particle separation efficiency (>96.27%) coupled low fluorescein purity (<4.46%) at 3 × 106 particles/min. The proposed methodology, characterized by ease production (simple dimensions), user-friendly (uniform rates both sheath sample inlets), efficient capabilities (typically mL min–1), demonstrates significant potential advancing microfluidic systems biological biomedical research.

Language: Английский

Citations

0
Microfluidic Hydraulic Oscillators: A Comprehensive Review of Emerging Biochemical and Biomedical Applications DOI
Md. Ahasan Ahamed, Mahmudul Hasan, Md. Emamul Kabir

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1350, P. 343793 - 343793

Published: Feb. 13, 2025

Language: Английский

Citations

0
Evaluation of mitochondrial activity via cellular interactions between adrenal and neuronal cells in a microfluidic coculture device DOI

Jae Seong Kim,

Huiseong Son,

Jihun Han

et al.

Biotechnology and Bioprocess Engineering, Journal Year: 2025, Volume and Issue: unknown

Published: April 16, 2025

Language: Английский

Citations

0
Challenges, Future Perspectives and Emerging Applications DOI

Daniel Gbenga Adekanmi,

Samuel Ebenezer Kayode,

Olaolu Samuel Awobifa

et al.

Engineering materials, Journal Year: 2025, Volume and Issue: unknown, P. 351 - 389

Published: Jan. 1, 2025

Language: Английский

Citations

0
Assessment of multiple hemorheological properties in microfluidic environment DOI
Yang Jun Kang

Physics of Fluids, Journal Year: 2024, Volume and Issue: 36(12)

Published: Dec. 1, 2024

Measuring and monitoring hemorheological properties provide valuable insights into diseases. To effectively detect impaired blood, it is necessary to quantify the multiple properties. However, most of previous methods only single blood property. They require bulky expensive syringe pumps for precise on–off control. In this study, resolve several issues, a novel method measuring (fluidic resistance, viscosity, time constant, compliance coefficient, red cell [RBC] aggregation index, RBC sedimentation index) proposed by analyzing images in microfluidic channels, where transient flow induced portable air-compression pump. A device consists an inlet, test chamber joined main channel, reservoir. The outlet connected air damper, which contributes stopping promptly. fluid circuit model channels constructed estimating rate pressure channel. First, used obtain rheological glycerin solution (30%). normalized difference between reference value less than 4%. Subsequently, adopted differences medium (1× phosphate-buffered saline, dextran solution: 20 mg/ml) hematocrit (30%–60%). All exhibit substantial with respect medium. yields comparable results when compared methods. conclusion, can measure channels.

Language: Английский

Citations

0