Antimonotungstate-Based Heterometallic Framework Formed by the Synergistic Strategy of In Situ-Generated Krebs-Type Building Units and the Substitution Reaction and Its High-Efficiency Biosensing KRAS Gene DOI
Peijun Gong,

Yanying Wang,

Jun‐Wei Zhao

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 64(1), P. 315 - 326

Published: Dec. 31, 2024

A novel antimonotungstate (AT)-based heterometallic framework {[Er(H2O)6]2[Fe4(H2pdc)4(B-β-SbW9O33)2]}·50H2O (1, H2pdc = pyridine-2,5-dicarboxylic acid) was obtained through a synergistic strategy of in situ-generated transition-metal-encapsulated polyoxometalate (POM) building units and the substitution reaction. Its structural unit is composed tetra-FeIII-substituted Krebs-type [Fe4(H2pdc)4(B-β-SbW9O33)2]6– subunit two [Er(H2O)6]3+ cations. This can be regarded as product carboxylic oxygen atoms ligands replacing active water [Fe4(H2O)10(B-β-SbW9O33)2]6– species. Apparently, action for ligands, together with coordination function Er3+ ions, plays connection role architecture three-dimensional (3-D) framework. Based on stability high redox activity 1, glassy carbon electrode modified by 1 used construction an electrochemical biosensor (ECBS). Thus, such 1-based ECBS sensitively detect KRAS gene (a key genetic marker identifying occurrence malignant tumors) displays low detection limit (0.106 pM), selectivity, reproducibility. work not only provides feasible approach to prepare multicomponent POM-based frameworks but also establishes new platform biosensing extends application scope functional materials.

Language: Английский

Spirulina-mediated biosynthesis of gold nanoparticles: an interdisciplinary study on antimicrobial, antioxidant, and anticancer properties DOI
Mohammad Aamir, Said Hassan, Amir Hamza Khan

et al.

Journal of Sol-Gel Science and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 2, 2025

Language: Английский

Citations

1
Polyoxometalate Nanomaterials for Tumor Phototherapy DOI Open Access
Xue Li, Xiangwei Liu, Tao Ying

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(5)

Published: Feb. 1, 2025

Abstract Polyoxometalates (POM) are a class of inorganic metal oxides with distinctive structural characteristics, compositional versatility, high catalytic efficacy, and convenient storage properties. In recent years, POM have shown considerable potential for mimicking enzyme activities. Besides their biological activities, been demonstrated to possess the ability sense diseases perform synergistic therapies based on redox near‐infrared absorption Similar metallic nanoparticles organic materials, these clusters also exhibit photothermal imaging therapeutic Based this, current review focuses exclusively application in therapy tumors. Furthermore, advantages issues associated POM‐based nanomaterials tumor discussed analyzed.

Language: Английский

Citations

1
Monitoring nutrient and beneficial elements in the topsoil: the function of weathered background and later surficial process on their distribution DOI
Bo Zhang,

Kai-Ning Lv,

Huan Li

et al.

Environmental Monitoring and Assessment, Journal Year: 2025, Volume and Issue: 197(3)

Published: Feb. 4, 2025

Language: Английский

Citations

0
Polyoxometalate-based materials in therapeutic and biomedical applications: current status and perspective DOI

Milad Moghadasi,

Mohammad Abbasi, Mohammad Ebrahim Mousavi

et al.

Dalton Transactions, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Recent advances in polyoxometalate (POM)-based materials with biomedical applications indicate significant potential the therapeutic field. The scientific community aims to advance these enhance bioorthogonal chemistry of POMs.

Language: Английский

Citations

0
Antimonotungstate-Based Heterometallic Framework Formed by the Synergistic Strategy of In Situ-Generated Krebs-Type Building Units and the Substitution Reaction and Its High-Efficiency Biosensing KRAS Gene DOI
Peijun Gong,

Yanying Wang,

Jun‐Wei Zhao

et al.

Inorganic Chemistry, Journal Year: 2024, Volume and Issue: 64(1), P. 315 - 326

Published: Dec. 31, 2024

A novel antimonotungstate (AT)-based heterometallic framework {[Er(H2O)6]2[Fe4(H2pdc)4(B-β-SbW9O33)2]}·50H2O (1, H2pdc = pyridine-2,5-dicarboxylic acid) was obtained through a synergistic strategy of in situ-generated transition-metal-encapsulated polyoxometalate (POM) building units and the substitution reaction. Its structural unit is composed tetra-FeIII-substituted Krebs-type [Fe4(H2pdc)4(B-β-SbW9O33)2]6– subunit two [Er(H2O)6]3+ cations. This can be regarded as product carboxylic oxygen atoms ligands replacing active water [Fe4(H2O)10(B-β-SbW9O33)2]6– species. Apparently, action for ligands, together with coordination function Er3+ ions, plays connection role architecture three-dimensional (3-D) framework. Based on stability high redox activity 1, glassy carbon electrode modified by 1 used construction an electrochemical biosensor (ECBS). Thus, such 1-based ECBS sensitively detect KRAS gene (a key genetic marker identifying occurrence malignant tumors) displays low detection limit (0.106 pM), selectivity, reproducibility. work not only provides feasible approach to prepare multicomponent POM-based frameworks but also establishes new platform biosensing extends application scope functional materials.

Language: Английский

Citations

0