NIR-responsive electrospun nanofiber dressing promotes diabetic-infected wound healing with programmed combined temperature-coordinated photothermal therapy
Jinlang Fu,
No information about this author
Ding Wang,
No information about this author
Zinan Tang
No information about this author
et al.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: July 1, 2024
Abstract
Background
Diabetic
wounds
present
significant
challenges,
specifically
in
terms
of
bacterial
infection
and
delayed
healing.
Therefore,
it
is
crucial
to
address
local
issues
promote
accelerated
wound
In
this
investigation,
we
utilized
electrospinning
fabricate
microgel/nanofiber
membranes
encapsulating
MXene-encapsulated
microgels
chitosan/gelatin
polymers.
Results
The
film
dressing
facilitates
programmed
photothermal
therapy
(PPT)
mild
(MPTT)
under
near-infrared
(NIR),
showcasing
swift
extensive
antibacterial
biofilm-disrupting
capabilities.
PPT
effect
achieves
prompt
sterilization
within
5
min
at
52
°C
disperses
mature
biofilm
10
min.
Concurrently,
by
adjusting
the
NIR
power
induce
heating
(42
°C),
stimulates
fibroblast
proliferation
migration,
significantly
enhancing
vascularization.
Moreover,
vivo
experimentation
successfully
validates
dressing,
underscoring
its
immense
potential
addressing
intricacies
diabetic
wounds.
Conclusions
MXene
microgel-loaded
nanofiber
employs
temperature-coordinated
therapy,
effectively
amalgamating
advantageous
features
high-temperature
low-temperature
promotion
It
exhibits
rapid,
broad-spectrum
capabilities,
exceptional
biocompatibility,
noteworthy
effects
on
promoting
cell
These
results
affirm
efficacy
our
highlighting
challenge
struggling
heal
due
infection.
Graphical
Language: Английский
Reversible light-responsive protein hydrogel for on-demand cell encapsulation and release
Acta Biomaterialia,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 1, 2025
Language: Английский
Iron(III)‐Based Triple Network High‐Strength Low‐Swelling Hydrogel
Huancai Zhao,
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Bing Peng,
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Yan Liu
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et al.
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(10)
Published: March 1, 2025
Abstract
In
this
study,
a
tough
chitosan‐gelatin‐polyacrylamide‐Fe
3+
(CGPA‐Fe
)
hydrogel
with
triple‐network
structure
is
successfully
synthesized
using
photoinitiated
free‐radical
polymerization.
The
designed
to
achieve
high‐strength,
low‐swelling
material
suitable
for
biomedical
applications.
Experimental
results
demonstrate
that
the
CGPA‐Fe
exhibits
excellent
mechanical
properties,
compressive
stress
of
5.29
MPa
and
modulus
1.27
under
80%
strain.
Furthermore,
shows
outstanding
fatigue
resistance,
retaining
nearly
100%
its
peak
after
10
compression
cycles.
It
also
displays
remarkable
self‐recovery
capabilities,
an
energy
dissipation
recovery
rate
exceeding
85%
60‐s
rest
period.
Regarding
swelling
behavior,
demonstrates
stability,
further
highlighting
potential
structural
summary,
represents
promising
candidate
materials.
This
study
provides
novel
approach
strategy
designing
advanced
hydrogels
superior
performance
stability.
Language: Английский
Reprogrammable shape morphing hydrogel modulated by synergistic photochromism and photoactuation
Xinyang Peng,
No information about this author
Hui Li,
No information about this author
Jie Xu
No information about this author
et al.
Chemical Engineering Journal,
Journal Year:
2025,
Volume and Issue:
unknown, P. 162103 - 162103
Published: March 1, 2025
Language: Английский
Wireless Electric Cues Mediate Autologous DPSC‐Loaded Conductive Hydrogel Microspheres to Engineer the Immuno‐Angiogenic Niche for Homologous Maxillofacial Bone Regeneration
Jiwei Sun,
No information about this author
Chao Xu,
No information about this author
Keqi Wo
No information about this author
et al.
Advanced Healthcare Materials,
Journal Year:
2023,
Volume and Issue:
13(6)
Published: Nov. 11, 2023
Abstract
Stem
cell
therapy
serves
as
an
effective
treatment
for
bone
regeneration.
Nevertheless,
stem
cells
from
marrow
and
peripheral
blood
are
still
lacking
homologous
properties.
Dental
pulp
(DPSCs)
derived
neural
crest,
in
coincidence
with
maxillofacial
tissues,
thus
attracting
great
interest
situ
regenerative
medicine.
However,
insufficient
number
heterogenous
alteration
of
seed
retard
further
exploration
DPSC‐based
tissue
engineering.
Electric
stimulation
has
recently
attracted
In
this
study,
a
novel
DPSC‐loaded
conductive
hydrogel
microspheres
integrated
wireless
electric
generator
is
fabricated.
Application
exogenous
cues
can
promote
stemness
maintaining
heterogeneity
suppression
unpredictable
differentiation
encapsulated
DPSCs.
Further
investigations
observe
that
signal
fine‐tunes
niche
by
improvement
on
DPSC‐mediated
paracrine
pattern,
evidenced
enhanced
angiogenic
behavior
upregulated
anti‐inflammatory
macrophage
polarization.
By
implanted
microspheres,
loaded
DPSCs
facilitates
the
construction
immuno‐angiogenic
at
early
stage
repair,
contributes
to
advanced
autologous
mandibular
defect
This
strategy
engineering
exhibits
promising
translational
therapeutic
potential
Language: Английский
Self-Adhesive, Anti-Freezing Multifunctional Zwitterionic Hydrogels with Lignin-Promoted Rapid Gelation for Flexible Strain Sensors
ACS Sustainable Chemistry & Engineering,
Journal Year:
2024,
Volume and Issue:
12(31), P. 11809 - 11820
Published: July 19, 2024
Language: Английский
Photoresponsive Smart Hydrogels and Their Versatile Applications: A Review
Asian Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
36(5), P. 1017 - 1026
Published: April 30, 2024
Stimuli
responsive
hydrogels
are
emerging
as
smart
materials
due
to
their
tunable
chemical
and
physical
properties
in
response
various
stimuli
like
pH,
temperature,
chemicals,
pressure,
electrical
or
light.
Photoresponsive
more
attractive
for
versatile
applications
can
be
manipulated
via
contact
free
fine
tuning
of
wavelength
intensity
If
designed
properly
photoresponsive
could
also
have
inherent
biocompatibility.
Their
responsiveness
along
with
biocompatibility
made
them
suitable
fields
starting
from
drug
delivery,
cell-culture
surface
modification
soft-robotics.
In
this
review
article,
basic
mechanisms
responsible
photo-responsiveness
potential
discussed.
Language: Английский
Plasmonic Nanocomposite for Visible Light‐Modulated Bimorph‐Actuator
Partha Kumbhakar,
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Santhosh Narendhiran,
No information about this author
S. K. Midya
No information about this author
et al.
Advanced Materials Technologies,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 4, 2024
Abstract
Soft
actuators
have
great
potential
applications
in
sophisticated
movement
and
sensitive
devices
due
to
their
flexible
nature,
good
interaction,
precise
control.
However,
existing
carbon‐based
optical
are
limited
response
under
visible
light
irradiation.
The
absorbance
of
the
carbon
nanostructure
brought
metallic
nanoparticle
into
soft
that
can
absorb
light.
This
study
introduces
a
new
type
plasmonic
photothermal‐bimorph
actuator,
using
graphene
oxide
(GO),
reduced
(rGO),
silver
nanorods
(Ag
NRs)
overcome
limitations
traditional
actuators.
bimorph
film
is
actuated
by
near‐infrared
stimuli
with
various
power
densities
showing
reversible
deformation
behavior.
actuator
shows
significant
bending
associated
≈50°
change
angle
irradiation
time
≈5
±
1
sec.
Furthermore,
smart
photo‐controlled
non‐contact
switch
fabricated
based
on
photo‐thermal
conversion
properties,
demonstrating
perfect
integration
density
functional
theory
molecular
dynamics
calculations
provide
an
additional
understanding
external
stimulus.
Using
illustrative
demonstrations
actuators,
these
results
hint
at
method
for
generating
multipurpose
light‐based
robots,
supporting
approach
developing
locking
system.
Language: Английский