Emerging Trends in Integrated Digital Microfluidic Platforms for Next-Generation Immunoassays DOI Creative Commons

Kaixin Su,

Jiaqi Li, Hailan Liu

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(11), P. 1358 - 1358

Published: Nov. 8, 2024

Technologies based on digital microfluidics (DMF) have made significant advancements in the automated manipulation of microscale liquids and complex multistep processes. Due to their numerous benefits, such as automation, speed, cost-effectiveness, minimal sample volume requirements, these systems are particularly well suited for immunoassays. In this review, an overview is provided diverse DMF platforms applications immunological analysis. Initially, droplet-driven electrowetting dielectric (EWOD), magnetic manipulation, surface acoustic wave (SAW), other related technologies briefly introduced. The preparation then described, including material selection, fabrication techniques droplet generation. Subsequently, a comprehensive account integration with various immunoassay offered, encompassing colorimetric, direct chemiluminescence, enzymatic electrosensory, Ultimately, potential challenges future perspectives burgeoning field delved into.

Language: Английский

Emerging Trends in Integrated Digital Microfluidic Platforms for Next-Generation Immunoassays DOI Creative Commons

Kaixin Su,

Jiaqi Li, Hailan Liu

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(11), P. 1358 - 1358

Published: Nov. 8, 2024

Technologies based on digital microfluidics (DMF) have made significant advancements in the automated manipulation of microscale liquids and complex multistep processes. Due to their numerous benefits, such as automation, speed, cost-effectiveness, minimal sample volume requirements, these systems are particularly well suited for immunoassays. In this review, an overview is provided diverse DMF platforms applications immunological analysis. Initially, droplet-driven electrowetting dielectric (EWOD), magnetic manipulation, surface acoustic wave (SAW), other related technologies briefly introduced. The preparation then described, including material selection, fabrication techniques droplet generation. Subsequently, a comprehensive account integration with various immunoassay offered, encompassing colorimetric, direct chemiluminescence, enzymatic electrosensory, Ultimately, potential challenges future perspectives burgeoning field delved into.

Language: Английский

Citations

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