Organic Reactivity Matters for the Emergence of Life: Kinetic Barriers and Molecular Diversity Are Suggested as Crucial Factors by Emerging Autonomous System Models DOI Creative Commons
Robert Pascal

ChemSystemsChem, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Abstract The idea that organic chemistry can gradually self‐organize towards the emergence of life has been challenged by views considering most important driver should be existence a crucial thermodynamic disequilibrium. In this work, past are critically addressed and mechanism through which disequilibrium promote development organized systems is suggested. This analysis based on propensity carbon to form covalent bonds with other elements, usually corresponds deep energy wells generating high kinetic barriers hindering reactions. Potential associated considered as storing prepaid entropy loss within potential surface therefore constitute giving room for subsequent self‐organization processes. notion Kinetically Stable Thermodynamically Activated (KSTA) compounds gives rise possibility alternative pathways non‐linear autocatalytic As working in far‐from‐equilibrium context, like molecular machines, parameters determining how they proceed change, suggests interactions between fields machines could mutually beneficial.

Language: Английский

Organic Reactivity Matters for the Emergence of Life: Kinetic Barriers and Molecular Diversity Are Suggested as Crucial Factors by Emerging Autonomous System Models DOI Creative Commons
Robert Pascal

ChemSystemsChem, Journal Year: 2025, Volume and Issue: unknown

Published: March 13, 2025

Abstract The idea that organic chemistry can gradually self‐organize towards the emergence of life has been challenged by views considering most important driver should be existence a crucial thermodynamic disequilibrium. In this work, past are critically addressed and mechanism through which disequilibrium promote development organized systems is suggested. This analysis based on propensity carbon to form covalent bonds with other elements, usually corresponds deep energy wells generating high kinetic barriers hindering reactions. Potential associated considered as storing prepaid entropy loss within potential surface therefore constitute giving room for subsequent self‐organization processes. notion Kinetically Stable Thermodynamically Activated (KSTA) compounds gives rise possibility alternative pathways non‐linear autocatalytic As working in far‐from‐equilibrium context, like molecular machines, parameters determining how they proceed change, suggests interactions between fields machines could mutually beneficial.

Language: Английский

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