Ultrasound treatment inhibits SARS-CoV-2 in vitro infectivity DOI Creative Commons
Flávio P. Veras, Gilberto M. Nakamura, Marcelo A. Pereira‐da‐Silva

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 21, 2022

The global spreading of SARS-CoV-2 and the emergence new variants underscore ongoing need to develop vaccines antiviral drugs. While electromagnetic acoustic waves have well-known virucidal properties, their application in therapeutic settings has been limited due harming effects biological matter. Here, we investigates potential ultrasound interfere with SARS-CoV-2. Specifically, study 1–20 MHz frequency range determine impact on viral envelope Our vitro experiments demonstrate exhibits a effect without production heat or cavitation. This offers promising physics-based approach combat potentially other spherical viruses, broadening scope treatments.

Language: Английский

Can prenatal ultrasound predict adverse neonatal outcomes in SARS-CoV-2–affected pregnancies? DOI Creative Commons
Jenny Y. Mei, Thalia Mok, Mary Catherine Cambou

et al.

American Journal of Obstetrics & Gynecology MFM, Journal Year: 2023, Volume and Issue: 5(9), P. 101028 - 101028

Published: June 8, 2023

On the basis of available data, at least 1 ultrasound assessment pregnancies recovering from SARS-CoV-2 infection is recommended. However, reports on prenatal imaging findings and potential associations with neonatal outcomes following in pregnancy have been inconclusive.

Language: Английский

Citations

5
COVID-19 during pregnancy could potentially affect placental function DOI Creative Commons
Shoichi Magawa, Masafumi Nii, Naosuke Enomoto

et al.

The Journal of Maternal-Fetal & Neonatal Medicine, Journal Year: 2023, Volume and Issue: 36(2)

Published: Oct. 8, 2023

COVID-19 is an ongoing pandemic and has been extensively studied. However, the effects of during pregnancy, particularly on placental function, have not verified. In this study, we used blood oxygen level-dependent magnetic resonance imaging (BOLD-MRI) to evaluate whether incidence pregnancy any lasting with respect oxygenation.This a case-control in which eight cases singleton pregnancies before 30 weeks gestation mothers were included. Placental oxygenation was evaluated using BOLD-MRI after 32 gestation. consecutively performed under normoxia (21% O2), hyperoxia (100% for 4 min each. Individual time-activity curves calculate peak score (peakΔR2*) time from start maternal administration peakΔR2* (time peakΔR2*). Eighteen COVID-19-free normal previous study as control group.No significant differences found between two groups regarding background, number days delivery, birth weight, weight. The parameter significantly decreased group (8 ± 3 vs. 5 1, p < .001); however, there no difference (458 74 s 471 33 s, = .644).In COVID-19-affected patients. even post-illness, but had effect fetal growth; further investigation possible fetus mother warranted.

Language: Английский

Citations

4
Effects of permanent placental injury due to severe acute respiratory syndrome coronavirus 2 infection during pregnancy on the feto-placental circulation: a cross-sectional study DOI Open Access
Mihriban Kılçar, Ümran Kılınçdemir Turgut, Kemal Kürşat Bozkurt

et al.

Revista da Associação Médica Brasileira, Journal Year: 2024, Volume and Issue: 70(2)

Published: Jan. 1, 2024

SUMMARY OBJECTIVE: The aim of this study was to evaluate the effects permanent placental injury due a severe acute respiratory syndrome coronavirus 2 infection during pregnancy on feto-placental circulation. METHODS: In cross-sectional study, 83 pregnant women with planned deliveries were divided into two groups according their statuses pregnancy. Their demographic parameters, obstetric histories, and prenatal risks evaluated. A fetal Doppler ultrasound examination performed for all participants, umbilical artery middle cerebral parameters obtained. Postpartum placentas examined pathological findings under appropriate conditions. All evaluated Amsterdam consensus criteria. Mann-Whitney U test, Student’s t-test, chi-square test used comparisons. RESULTS: Demographic statistically similar, except that they borderline significant gestational weeks at delivery (p=0.044). placenta, regardless trimester exposure viral infection, perivillous fibrin deposition villus dystrophic calcification more common in group (p=0.016 p=0.048, respectively) than 1. between groups, no difference found pulsatile index, cerebro-placental ratio values. CONCLUSION: Severe causes an increase placenta. Placental caused by virus does not affect parameters.

Language: Английский

Citations

1
Increased risk of fetal left–right asymmetry disorders associated with maternal SARS-CoV-2 infection during the first trimester DOI Creative Commons
Yang Li, Yuemei Wang,

Haifang Wu

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: May 19, 2024

Abstract Our center has observed a substantial increase in the detection rate of fetal left–right(LR) asymmetry disorders between March and May 2023. This finding raised concerns because these pregnant women experienced peak outbreak SARS-CoV-2 China during their first trimester. To explore relationship maternal infection LR disorders. A retrospective collection clinical ultrasound data diagnosed as was conducted from January 2018 to December The case–control study involved fetuses with normal 1:1 ratio. We evaluated compared findings without infection. Student t -test utilized compare continuous variables, while chi-squared test employed for univariable analyses. incidence 2023 follows: 0.17‰, 0.63‰, 0.61‰, 0.57‰, 0.59‰, 3.24‰, respectively. total 30 were included. found that (96.67% vs 3.33%, P = .026) trimester (96.55% 3.45%, .008) identified risk factors. odds ratio values 10.545 (95% CI 1.227, 90.662) 13.067 1.467, 116.419) In cases trimester, majority infections (88.1%, 37/42) occurred 5 6 weeks gestation. 43.7% (66/151) disorder had associated malformations, 90.9% (60/66) exhibited cardiac malformations. significantly increases disorders, particularly when occurs gestation weeks. most common malformation is heart malformation.

Language: Английский

Citations

1
COVID-19 is associated with early emergence of preeclampsia: results from a large regional collaborative DOI Creative Commons
Yasmin Hasbini, Robert J. Sokol,

Pooja M. Green

et al.

The Journal of Maternal-Fetal & Neonatal Medicine, Journal Year: 2024, Volume and Issue: 37(1)

Published: Jan. 2, 2024

To investigate the relationship between preeclampsia and SARS-CoV-2 infection during pregnancy.

Language: Английский

Citations

1
Fetal Biometry and Doppler Assessment of Pregnant Women with COVID-19 DOI Creative Commons

Hiba Ahmed Suhail,

D.M. Abdulrahman,

Abee Ahmed

et al.

International Journal of Biomedicine, Journal Year: 2022, Volume and Issue: 12(4), P. 554 - 559

Published: Dec. 5, 2022

Background: The world has changed radically because of the worldwide COVID-19 pandemic. SARS-CoV-2, a unique strain large, enveloped single-stranded RNA viruses, that spread around world. primary objective this research was to assess fetal growth velocity in pregnancies complicated by SARS-CoV-2 infection and those were not. secondary determine if may affect maternal Doppler readings. Methods Results: A total 250 pregnant women diagnosed with (Case group) compared 300 healthy (Control prospective case-control study Mosul from February 20 October 20, 2021. Infections during pregnancy detected verified using real-time reverse transcriptase-polymerase chain reaction (RT-PCR). All ultrasound exams done 24 40 weeks. Measuring parameters ultrasonography included plasticity resistive indices (PI, RI), as well cerebroplacental ratio computed according gestational age. Fetal development utero assessed measuring biometric markers, such parietal diameter, head size, belly circumference, leg length, estimated weight every four US scans second third trimester showed no evidence congenital abnormalities (P=0.7047). There significant incidence cesarean delivery (P=0.0000) lower activity at birth Case group, Control group. Anticoagulant treatment not associated an increased risk postpartum hemorrhage Also, there differences biparietal diameter femur length between groups trimesters, both studies throughout (35-37 weeks) trimesters yielded PI RI indices.

Language: Английский

Citations

5
Review On Foetal Position Detection Using Different Techniques DOI

I Jeya Daisy,

G Diyaneshwaran,

K Ravivarmaa

et al.

Published: May 11, 2023

Modern obstetrics places a high priority on foetal health monitoring. Although movement is frequently used as proxy for health, it difficult to accurately monitor over an extended period of time without causing any harm. In high-risk pregnancies and in moms who have previously experienced miscarriages, highly helpful determine the foetus position because, majority cases, incorrect results both maternal mortality. Pregnant women may benefit from design construction device that can identify location foetus. Recent years seen development few accelerometer-based systems address frequent problems with ultrasound measurement allow remote, self-managed monitoring throughout pregnancy. The optimum body-worn accelerometers, data processing, deep learning methods movement. This study will explore four alternative techniques determining Ultrasonograms are most popular detection. wearable ambulatory known Femom, which has been made available home prescription, also be Deep thermal imaging cameras utilised

Language: Английский

Citations

2
Impacto de la infección materna asintomática por SARS-CoV-2 sobre el crecimiento fetal DOI
Alexandra Bonmatí‐Santané, Anna Maroto,

Clara Martínez‐Diago

et al.

Clínica e Investigación en Ginecología y Obstetricia, Journal Year: 2022, Volume and Issue: 49(3), P. 100756 - 100756

Published: Feb. 18, 2022

Language: Английский

Citations

3
Placental and Doppler ultrasound findings in pregnant women with SARS-CoV-2 infection DOI Creative Commons
Eva María Soto Sánchez,

Carmen López-Gorosabel,

Ana Belén Ibáñez-Santamaría

et al.

AJOG Global Reports, Journal Year: 2023, Volume and Issue: 3(2), P. 100190 - 100190

Published: March 15, 2023

Several viral infections cause changes in the placenta. Cytomegalovirus, herpes viruses, and HIV increased placental thickness; Zika virus induces focal regions of necrosis; parvovirus B19 causes a structural injury. Umbilical flow can be considered direct measurement vascular function.This study aimed to compare ultrasound umbilical Doppler findings pregnant women who tested positive or negative for SARS-CoV-2. Our work confirm suspicion infection consequence fetal physiopathology.Fifty-seven SARS-CoV-2 at time 1 month before scan were evaluated. Cases included 9 first trimester, 16 second 32 third trimester scans. For comparison, 110 (controls) They 19 their 43 48 trimester. Controls asymptomatic last 72 hours scan. Fetal biometry, thickness, lakes vein parameters, including venous cross-sectional area (mean transverse diameter radius vein, mean velocity vein), blood evaluated.Placental thickness (in millimeter) was significantly higher group with (53.82 [10-115]) than control (33.82 [12-66]; P<.001) trimesters. The frequency >4 (28/57 [50.91%]) (7/110 [6.36]; all 3 (12.45 [5.73-21]) (10.81 [6.31-18.80]; P=.001) milliliter per minute) (389.9 [6.52-1496.1]) (305.05 [3.11-1441]; P=.05) trimesters.Significant differences documented. Placental lakes,

Language: Английский

Citations

1
Ultrasound Placental Remodeling Patterns and Pathology Characteristics in Patients with History of Mild SARS-CoV-2 Infection during Pregnancy DOI Creative Commons
Adelina Staicu, Camelia Albu, Georgiana Nemeti

et al.

Diagnostics, Journal Year: 2023, Volume and Issue: 13(6), P. 1200 - 1200

Published: March 22, 2023

Introduction: This research aims to describe a progressive pattern of ultrasound placental remodeling in patients with history SARS-CoV-2 infection during pregnancy. Materials and Methods: was longitudinal, cohort study which enrolled 23 pregnant women former mild the current Four obstetricians analyzed images from different gestational ages following COVID identified presence degree remodeling. We assessed inter-rater agreement interclass correlation coefficients. Pathology workup included biometry, macroscopic microscopic examination. Results: Serial evaluation morphology revealed starting 30-32 weeks gestation towards term, occurring approximately 8-10 after infection. Placental changes-the "starry sky" appearance "white line" along basal plate-were all cases. Most placentas presented normal subchorionic perivillous fibrin depositions focal stem villi deposits. Focal calcifications were described only 13% Conclusions: two signs as potential markers viral shedding SARS-CoV-2. The most likely pathology correspondence for imaging aspect is and, respectively, massive deposits

Language: Английский

Citations

1