Ultrasound treatment inhibits SARS-CoV-2 in vitro infectivity DOI Creative Commons
Flávio P. Veras, Gilberto M. Nakamura, Marcelo A. Pereira‐da‐Silva

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 21, 2022

The global spreading of SARS-CoV-2 and the emergence new variants underscore ongoing need to develop vaccines antiviral drugs. While electromagnetic acoustic waves have well-known virucidal properties, their application in therapeutic settings has been limited due harming effects biological matter. Here, we investigates potential ultrasound interfere with SARS-CoV-2. Specifically, study 1–20 MHz frequency range determine impact on viral envelope Our vitro experiments demonstrate exhibits a effect without production heat or cavitation. This offers promising physics-based approach combat potentially other spherical viruses, broadening scope treatments.

Language: Английский

Evaluation of the effect of SARS-COV-2 infection on Doppler ultrasound and placental findings of pregnant women: A systematic review and meta-analysis. DOI Creative Commons

Lanying Chen,

Tingting Yin,

D. Cai

et al.

ULTRASONOGRAPHY, Journal Year: 2024, Volume and Issue: 43(6), P. 424 - 437

Published: July 15, 2024

Purpose: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect the human placenta and has been shown to have an adverse effect on Doppler ultrasound parameters placental features. However, specific effects of SAS-CoV-2 infection fetal-placental unit in pregnant women remain unclear. The aim this systematic review meta-analysis was evaluate impact SARS-CoV-2 findings women.Methods: A search conducted using four electronic databases (PubMed, Embase, Scopus, Cochrane Library) select publications published peer-reviewed journals written English. Odds ratios (ORs) were calculated, along with their 95% confidence intervals (CIs). Heterogeneity assessed Q I2 statistics appropriate P-value. analysis used RevMan 5.3.Results: This included 1,210 from 10 case-control studies. SARS-CoV-2–infected exhibited higher likelihoods abnormalities (OR, 2.62; CI, 1.66 4.13), aberrant values 1.95; 1.16 3.27), abnormal cerebroplacental ratio 2.68; 1.52 4.75), altered fetoplacental circulation 1.56; 1.07 2.28), increased thickness venous lakes 1.85; 1.25 2.72).Conclusion: According meta-analysis, infected are more likely experience ultrasonography abnormalities, including thickness, lakes, circulation, ratio. limited number studies requires larger sample sizes validate enhance evidence.

Language: Английский

Citations

0

PostCOVID-19 Impact on Perinatal Outcomes DOI Creative Commons
Gaukhar Kurmanova, А.К. Аязбеков, Аlmagul Kurmanova

et al.

Diagnostics, Journal Year: 2024, Volume and Issue: 15(1), P. 57 - 57

Published: Dec. 29, 2024

Background. Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2) infection during pregnancy was associated with a number of adverse outcomes, including miscarriage, preeclampsia, preterm birth, and stillbirth. The virus persistence can last for long time, the consequences previous coronavirus are currently under study. Objectives. This study aimed to establish clinical features course childbirth in women history asymptomatic disease 2019 (COVID-19). Methods. conducted Regional Perinatal Center N3 Turkestan city, Kazakhstan. A total 229 participants were enrolled comprising individuals (n = 133, exposed group) from August September 2021 COVID-19 without one same period 96, unexposed group). Results. There is statistically significant strong association between development oligohydramnios (φ 0.743, p < 0.001), medium strength presence anemia 0.254, abnormal placenta 0.011), cord entanglement 0.343, 0.000), low birth weight 0.356, 0.001) stillbirth 0.293, 0.001). Conclusions. past pregnant has long-term form oligohydramnios; and, as result, perinatal outcomes

Language: Английский

Citations

0

A case of temporary anhydramnios after COVID-19 infection DOI Creative Commons

Yoshifumi Kasuga,

Yoshikazu Sou,

Mio Fukuoka

et al.

European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal Year: 2022, Volume and Issue: 272, P. 255 - 256

Published: April 9, 2022

Language: Английский

Citations

2

Doppler ultrasound findings in symptomatic pregnant women diagnosed with COVID-19 DOI
Selamı Erdem,

Mehmet İrfan Külahçıoğlu

Journal of Obstetrics and Gynaecology, Journal Year: 2022, Volume and Issue: 42(7), P. 2680 - 2683

Published: June 4, 2022

The primary aim of this study was to investigate the potential impact severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on maternal and foetal Doppler findings. ultrasound findings were compared in 40 pregnant women diagnosed with COVID-19 disease who required hospitalisation (group 1) 30 healthy 2). Maternal characteristics birth histories recorded. Body mass index, gestational week at birth, type delivery, oligihydroamnios, pre-term (<37 weeks), low weight (<10 percentile), perinatal death f1st 5th minute Apgar scores Birth weights biophysical profile (BPP) group 1 significantly lower than those 2. There a statistically significant between-group difference umbilical artery pulsatility index (PI), resistive (RI), middle cerebral (MCA) PI, MCA RI, mean uterine (UtA) UtA RI cerebroplacental ratio (CPR), parameters used evaluate foetal-maternal blood flow. In hospitalised, all indicators flow impaired, BPP these patients controls.Impact statementWhat is already known subject? Foetal vascular malperfusion characterised by decidual arteriopathy have been reported pathologies placentas from SARS-CoV-2 infection.What results add? It determined that disrupted flow.What implications are for clinical practice and/or further research? biometric measurements may be useful follow-up outcomes COVID-19.

Language: Английский

Citations

2

Ultrasound treatment inhibits SARS-CoV-2 in vitro infectivity DOI Creative Commons
Flávio P. Veras, Gilberto M. Nakamura, Marcelo A. Pereira‐da‐Silva

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2022, Volume and Issue: unknown

Published: Nov. 21, 2022

The global spreading of SARS-CoV-2 and the emergence new variants underscore ongoing need to develop vaccines antiviral drugs. While electromagnetic acoustic waves have well-known virucidal properties, their application in therapeutic settings has been limited due harming effects biological matter. Here, we investigates potential ultrasound interfere with SARS-CoV-2. Specifically, study 1–20 MHz frequency range determine impact on viral envelope Our vitro experiments demonstrate exhibits a effect without production heat or cavitation. This offers promising physics-based approach combat potentially other spherical viruses, broadening scope treatments.

Language: Английский

Citations

1