Effect of enrofloxacin on clinical parameters and mucociliary system of broilers challenged with H9N2 avian influenza/infectious bronchitis viruses DOI Creative Commons
Mohammad Abbasnia, Najmeh Mosleh, H. Dadras

et al.

Veterinary Medicine and Science, Journal Year: 2024, Volume and Issue: 10(2)

Published: Feb. 28, 2024

Abstract Background Effect of antibacterials on mucociliary system and clinical outcome chickens with mixed viral respiratory conditions is not properly addressed. Objective We evaluated enrofloxacin effects parameters broilers challenged H9N2/IB viruses. Methods Broilers (105), at the age 25 days, were randomly allocated into three groups: Group 1 (negative control), no treatment; 2 (positive control [PC]) by intranasal intraocular route. 3 (antibiotic [AB]‐treated) also received started after manifestation signs (day post‐challenge [pc]) continued for 5 days. Results Administration AB was associated appreciable changes in body weight, feed conversion ratio (FCR) or severity although it slightly reduced mortality rate as compared to PC group ( p > 0.05). Virus shedding period number virus positive tracheal caecal tonsil samples statistically similar between groups. In necropsy, most profound effect decreased pleuropneumonia score day 12 pc. Histopathological lesion scores same However, administration increased goblet cells, ciliostasis. Conclusions found a weak H9N2/IB‐infected chickens. Considering risks treatment broiler chickens, results this small‐scale study do encourage benefit use these diseases.

Language: Английский

Effect of enrofloxacin on clinical parameters and mucociliary system of broilers challenged with H9N2 avian influenza/infectious bronchitis viruses DOI Creative Commons
Mohammad Abbasnia, Najmeh Mosleh, H. Dadras

et al.

Veterinary Medicine and Science, Journal Year: 2024, Volume and Issue: 10(2)

Published: Feb. 28, 2024

Abstract Background Effect of antibacterials on mucociliary system and clinical outcome chickens with mixed viral respiratory conditions is not properly addressed. Objective We evaluated enrofloxacin effects parameters broilers challenged H9N2/IB viruses. Methods Broilers (105), at the age 25 days, were randomly allocated into three groups: Group 1 (negative control), no treatment; 2 (positive control [PC]) by intranasal intraocular route. 3 (antibiotic [AB]‐treated) also received started after manifestation signs (day post‐challenge [pc]) continued for 5 days. Results Administration AB was associated appreciable changes in body weight, feed conversion ratio (FCR) or severity although it slightly reduced mortality rate as compared to PC group ( p > 0.05). Virus shedding period number virus positive tracheal caecal tonsil samples statistically similar between groups. In necropsy, most profound effect decreased pleuropneumonia score day 12 pc. Histopathological lesion scores same However, administration increased goblet cells, ciliostasis. Conclusions found a weak H9N2/IB‐infected chickens. Considering risks treatment broiler chickens, results this small‐scale study do encourage benefit use these diseases.

Language: Английский

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