Bioactive Matters based on Natural Product for Cardiovascular Diseases DOI Creative Commons
L. Zhong,

Xiaoying Tan,

Wenhui Yang

et al.

Smart Materials in Medicine, Journal Year: 2024, Volume and Issue: 5(4), P. 542 - 565

Published: Nov. 16, 2024

Language: Английский

Biological activity analysis of baicalin nanodrugs: Nanosizing enhances antiviral and anti-inflammatory effects in the treatment of viral pneumonia DOI Creative Commons

Chenqi Chang,

Chang Lu,

Yu Zheng

et al.

Journal of Pharmaceutical Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 101201 - 101201

Published: Jan. 1, 2025

Language: Английский

Citations

0
The key role of natural products in the fight against endometrial Cancer DOI

Wen Chen,

Wencheng Zhou, Songjun Liu

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 151, P. 114344 - 114344

Published: Feb. 26, 2025

Language: Английский

Citations

0
Mannose-modified erythrocyte membrane-coated Chuanmingshen violaceum polysaccharide PLGA nanoparticles to improve immune responses in mice DOI

Shuyao Yang,

Xinnan Zhang, Yao Wang

et al.

International Immunopharmacology, Journal Year: 2025, Volume and Issue: 152, P. 114450 - 114450

Published: March 12, 2025

Language: Английский

Citations

0
Synthesis and preliminary cytotoxicity evaluation of water soluble pentacyclic triterpenoid phosphonates DOI Creative Commons
Jevgeņija Lugiņina, Vladislavs Kroškins,

Rihards Lācis

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 14, 2024

Abstract Synthesis, solubility and cytotoxicity evaluation of anionic phosphonates derived from betulin, betulinic acid, oleanolic acid ursolic is reported. Phosphonate moieties were successfully installed at terpenoid C28 by carboxylic deprotonation/alkylation sequence using (dimethoxyphosphoryl)methyl trifluoromethanesulfonate as alkylation reagent. Also, betulin-derived ether-linked bis-phosphonate obtained characterized. After demethylation in the presence TMSI resulting phosphonic acids transformed into their disodium salts. All target compounds display excellent water solubility, which was determined qNMR D 2 O. Cytotoxicity tests performed different concentrations each compound (10–50 µM) against human osteosarcoma cell line MG-63 osteoblast precursor MC3T3-E1. Improved aqueous low profile newly designed triterpenoid reveal high potential for various medicinal chemistry pharmacological applications future.

Language: Английский

Citations

1
Stability and Efficacy of Pterostilbene Nanoliposomes in Cosmetic Applications: A Comprehensive Study DOI Creative Commons
Jianxin Li,

H. T. Li,

Pengfei Ye

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: unknown, P. 100056 - 100056

Published: Oct. 1, 2024

Language: Английский

Citations

0
Bioactive Matters based on Natural Product for Cardiovascular Diseases DOI Creative Commons
L. Zhong,

Xiaoying Tan,

Wenhui Yang

et al.

Smart Materials in Medicine, Journal Year: 2024, Volume and Issue: 5(4), P. 542 - 565

Published: Nov. 16, 2024

Language: Английский

Citations

0