Structure Protects Function: A Multilevel Engineered Surface Modification Renders the Surface of Titanium Dental Implants Resistant to Bacterial Colonization

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 27, 2025

The global dental implant market is projected to reach $9.5 billion by 2032, growing at a 6.5% compound annual growth rate due the rising prevalence of diseases. Importantly, this raises concerns about postoperative infections, which present significant challenges within our healthcare system and lead two-thirds failure for infected implants. In study, we an innovative multilevel coating that makes surface titanium implants resistant bacterial colonization, thereby minimizing risk infection development. This features nanometer-thick biohybrid layer combined with microgroove microstructuring, creating physical barriers enhance stability biohybrids against mechanical abrasion. Our demonstrates excellent biocompatibility strong antifouling properties undiluted blood plasma proteins. Furthermore, combination microstructuring remains stable under prolonged stress simulation effectively repels clinically relevant bacteria, achieving 99% reduction in colonization on implant. These findings underscore potential approach prevent implant-associated infections highlight critical role engineering ensuring long-term performance.

Language: Английский

Enhanced Antibacterial and Corrosion Resistance Performance of Fluorine-Doped Diamond-Like Carbon Coatings on 316 L Stainless Steel

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: unknown, P. 114666 - 114666

Published: April 1, 2025

Language: Английский