Gluing together a fragmented healthcare system for geriatrics will be hard. It's time for united action DOI
Christopher C. Colenda, William B. Applegate

Journal of the American Geriatrics Society, Journal Year: 2024, Volume and Issue: 72(4), P. 993 - 1003

Published: March 18, 2024

Abstract “Gluing” together integrated Geriatric Clinical Service lines (GCSL) within the US healthcare system is a significant challenge. Reasons encompass health professional workforce shortages, inconsistent requirements for geriatric educational competencies among disciplines, preconceived ageist attitudes about older adults with complex illnesses, and infrastructure that not aligned longitudinal interdisciplinary care needs adults. This review focuses on three major characteristics of have impeded widespread dissemination GCSLs: (1) US's historical fee service (FFS) reimbursement system; (2) increasing reliance upon disease specific specialty services patients resulted from advances in medicine; (3) rising consolidation systems over last 30 years. Three options are also provided might help change current future trajectories local political advocacy to implement policy legislation; expand physician by nontraditional means; reprioritize expansionist corporate behavior. Each these interventions will be hard achieve, but it time unite if GCSLs thrive as pathways improve outcomes medical, cognitive neuropsychiatric disorders.

Language: Английский

Tremendous Fidelity of Vitamin D3 in Age-related Neurological Disorders DOI

Manjari Skv,

Sharon Mariam Abraham,

Omalur Eshwari

et al.

Molecular Neurobiology, Journal Year: 2024, Volume and Issue: 61(9), P. 7211 - 7238

Published: Feb. 19, 2024

Language: Английский

Citations

6
Advances in the understanding of the pathophysiology of schizophrenia and bipolar disorder through induced pluripotent stem cell models DOI Open Access
Andrea Perrottelli,

Francesco Flavio Marzocchi,

Edoardo Caporusso

et al.

Journal of Psychiatry and Neuroscience, Journal Year: 2024, Volume and Issue: 49(2), P. E109 - E125

Published: March 15, 2024

The pathophysiology of schizophrenia and bipolar disorder involves a complex interaction between genetic environmental factors that begins in the early stages neurodevelopment. Recent advancements field induced pluripotent stem cells (iPSCs) offer promising tool for understanding neurobiological alterations involved these disorders and, potentially, developing new treatment options. In this review, we summarize results iPSC-based research on disorder, showing disturbances neurodevelopmental processes, imbalance glutamatergic-GABAergic transmission neuromorphological alterations. limitations reviewed literature are also highlighted, particularly methodological heterogeneity studies, limited number studies iPSC models both diseases simultaneously, lack in-depth clinical characterization included samples. Further needed to advance knowledge common disease-specific pathophysiological features promote development

Language: Английский

Citations

6
Neurobiological and anti-aging benefits of yoga: A comprehensive review of recent advances in non-pharmacological therapy DOI Creative Commons
Qiaoyan Chen

Experimental Gerontology, Journal Year: 2024, Volume and Issue: 196, P. 112550 - 112550

Published: Sept. 2, 2024

Aging is an unavoidable process marked by numerous physiological and psychological changes that profoundly impact overall health quality of life. As the global population ages, there a growing interest in non-pharmacological therapies can mitigate adverse effects aging promote longevity. This narrative review explores broad spectrum mechanisms offering anti-aging benefits, with special emphasis on holistic practices such as yoga, meditation, lifestyle interventions. These influence critical biological processes, including reducing oxidative stress, modulating chronic inflammation, enhancing immune function, preserving telomere length-key markers cellular aging. Additionally, these contribute to improved cardiovascular health, musculoskeletal strength, mental well-being, fostering comprehensive approach healthy Yoga, for instance, combines physical postures, breath control, meditation enhance flexibility, clarity, emotional balance. Meditation are shown reduce stress improve cognitive further supporting Lifestyle modifications, diet regular activity, complement promoting vitality risk age-related diseases. underscores potential integrating strategies into daily routines resilience against aging, life, extend healthspan. Furthermore, it highlights need continued research fully elucidate which exert their develop evidence-based guidelines implementation.

Language: Английский

Citations

6
Artificial light at night, MRI-based measures of brain iron deposition and incidence of multiple mental disorders DOI
Jianbo Jin, Wenxing Han, Teng Yang

et al.

The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 902, P. 166004 - 166004

Published: Aug. 5, 2023

Language: Английский

Citations

15
Socioeconomic status moderate the relationship between mental health literacy, social participation, and active aging among Chinese older adults: evidence from a moderated network analysis DOI Creative Commons

Yalian Huang,

Aibao Zhou,

Ping Tang

et al.

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 13, 2025

Language: Английский

Citations

0
Characteristics and Satisfaction with Services of Patients Attending A Geriatric Psychiatry Clinic in Southern India DOI Creative Commons

Sheeba Ninan,

Fathima Hanan Kilikkotte,

Aswin Kollamkandipalliyali

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

Abstract Specialist services like geriatric psychiatric clinics aim to provide a multidisciplinary and person-centred approach. There is not enough information available about the number type of such in India. In this descriptive paper, we detail provided sociodemographic clinical characteristics patients who have attended psychiatry outpatient clinic at Institute Mental Health Neurosciences, Kerala, Southern A specific data sheet was used transfer details weekly Geriatric Psychiatry Outpatient clinic. The uses comprehensive proforma assessment tool as appropriate. Short Assessment Patient Satisfaction Scale assess satisfaction with services. Between August 2023 March 2024, eighty Clinic. Men women were equal numbers (40, 50%). mean age attendees 68.91 (sd=6.87). Sixty-four (80%) had comorbid medical disorders. most common diagnosis dementia adjustment disorder (14; 17.5%). Eight (10%) each depression anxiety Regarding treatment, 48 (60%) prescribed psychotropic medications: 21 (26.3%) on antipsychotics, 37 (46.3%) antidepressants, 14 (17.5%) benzodiazepines. Most ‘very satisfied’ service, 47 (58.8%) scoring 27 or 28 SAPS, where maximum score 28. team brings blend skills approach care, rehabilitation.

Language: Английский

Citations

0
Differential Transcriptional Programs Reveal Modular Network Rearrangements Associated with Late-Onset Alzheimer’s Disease DOI Open Access
Alejandra Paulina Pérez-González, Guillermo de Anda‐Jáuregui, Enrique Hernández-Lemus

et al.

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(5), P. 2361 - 2361

Published: March 6, 2025

Alzheimer’s disease (AD) is a complex, genetically heterogeneous disorder. The diverse phenotypes associated with AD result from interactions between genetic and environmental factors, influencing multiple biological pathways throughout progression. Network-based approaches offer way to assess phenotype-specific states. In this study, we calculated key network metrics characterize the transcriptional structure organization in LOAD, focusing on genes implicated pathology within dorsolateral prefrontal cortex (DLPFC). Our findings revealed disease-specific coexpression markers metabolic functions. Additionally, significant differences were observed at both mesoscopic local levels control networks, along restructuring of gene functions into distinct modules. These results show molecular reorganization program occurring highlighting specific adaptations that may contribute or cellular responses pathological stressors. support development unified model for causal mechanisms AD, suggesting its manifestations arise working together produce disease’s complex clinical patho-phenotype.

Language: Английский

Citations

0
The potential of single session intervention approaches to enhance the mental health and resilience of older adults, care partners, and healthcare systems DOI Creative Commons
Sarah Bannon, Andy Rapoport, Allison J. Applebaum

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 5, 2025

Single-session interventions (SSIs) are mental health (MH) that intentionally involve a single encounter. In this commentary, we outline issues with existing models of MH care for older adults & their partners, how SSIs can address barriers, and considerations research. We encourage the development to increase accessibility, scalability, participation, cost-effectiveness interventions.

Language: Английский

Citations

0
Social Frailty Moderates the Association Between Gender and Life Satisfaction: Evidence from a Large-Scale Survey Among Indian Older Adults DOI

J Mufina Begam,

E.P. Abdul Azeez,

C. V. Irshad

et al.

Journal of Gerontological Social Work, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 20

Published: March 7, 2025

This study examined the role of gender, social frailty, depressive symptoms, and cognitive impairment on life satisfaction, along with interaction effect frailty between gender satisfaction. We used Longitudinal Ageing Study in India (LASI) Wave 1 data considered 23,345 older adults. Multivariate models, ordinary least squares regression, moderation analyses were conducted. The higher levels status symptoms reduced models revealed that relationship satisfaction was moderated by frailty. results indicate need to improve networks engagement among aging

Language: Английский

Citations

0
Factors Associated with Family Involvement or Lack Thereof in Caring for Mental Health Care Users: A Qualitative Study DOI Creative Commons
Nkhensani Florence Mabunda

Psychiatry International, Journal Year: 2025, Volume and Issue: 6(1), P. 30 - 30

Published: March 11, 2025

Family involvement in caring for people living with mental illness is significant ideal positive treatment outcomes. Studies show that there are common factors affect family members when involved health care. The study aimed to explore and describe the associated inadequate care users. A qualitative explorative, descriptive, contextual design was used. Purposive sampling used select data from MHCUs admitted long-term healthcare institutions. Data were collected concurrently focused group interviews users semi-structured members. Thematic analysis analyse data. Three themes emerged results include: attitude of towards carrying at home, burden users, lack knowledge among findings home discharged or granted leave absence, impacts odd behaviour As a result, returned hospital before expected return date.

Language: Английский

Citations

0