An in vitro assessment of the potential antidiabetic activity and cytotoxic effects of ethanolic and aqueous extracts from three invasive Australian acacias DOI Creative Commons
Daniel Buttner, Shanika Reddy, Trevor Koekemoer

et al.

South African Journal of Botany, Journal Year: 2021, Volume and Issue: 141, P. 1 - 11

Published: May 12, 2021

Acacia cyclops, saligna and mearnsii are characterized as prolific invasive alien plants (IAPs) presenting a substantial ecological economic burden on South Africa. While conventionally these species perceived weeds having little value, this study attempts to demonstrate their respective potential phytomedicinal resource in the treatment of type 2 diabetes – thereby incentivizing eradication. Moreover, aimed assess antidiabetic cytotoxic effects extracts from three Australian acacias vitro. The α-glucosidase ɑ-amylase activities ethanolic aqueous derived aerial tissues A. saligna, were investigated, followed by cytotoxicity assessment using Hoechst 33342-Propidium Iodide (PI) dual staining quantitative fluorescence microscopy human colon (Caco-2) cell line. Of screened, bark demonstrated highest inhibitory activity against α-amylase with an IC50 10.45 ± 3.79 μg/ml 2.35 0.61 leaf extract depicting strong (IC50 3.64 1.59 μg/ml) moderate 17.67 3.84 inhibition. values all significantly (p < 0.05) lower than Acarbose 330.71 28.36 Epigallocatechin gallate 68.2 8.34 μg/ml). All found be nontoxic at test concentrations Caco-2 cells confirmed Hoescht 33342-PI staining. Overall, findings presented provide first concurrent account Acacias Africa reporting alternative therapeutic option for diabetes.

Language: Английский

Futures for invasive alien species management: using bottom-up innovations to envision positive systemic change DOI Creative Commons
Julia van Velden, Reinette Biggs, Tanja Hichert

et al.

Sustainability Science, Journal Year: 2023, Volume and Issue: 18(6), P. 2567 - 2587

Published: Sept. 5, 2023

Abstract Invasive alien species (IAS) pose a key threat to biodiversity, the economy and human well-being, continue increase in abundance impact worldwide. Legislation policy currently dominate global agenda for IAS, although translation localised success may be limited. This calls wider range of responses transform IAS management. An under-appreciated strategy achieve come from bottom-up, experimental innovations (so-called “seeds”), which offer alternative visions what possible management future. We present an application participatory process that builds on such create future, with actionable pathways guide change. Through series workshops practitioners academics, we used this explore positive futures South Africa. then identified set domains change, could enable these actioned by appropriate stakeholders. The change highlight social–ecological nature sector, interconnected actions needed financial, cultural, social, technological governance spheres. Key were need shift mindsets values society regarding as well functional financing. futuring offers way interrogate scale bottom-up innovations, thereby creating optimism allowing stakeholders engage constructively represents important step fostering potential

Language: Английский

Citations

3
Education, Training and Capacity-Building in the Field of Biological Invasions in South Africa DOI Creative Commons
Marcus J. Byrne, Dorette du Plessis, Philip Ivey

et al.

Springer eBooks, Journal Year: 2020, Volume and Issue: unknown, P. 731 - 755

Published: Jan. 1, 2020

Language: Английский

Citations

8
The dominating influence of efficacy above management strategy in the long-term success of alien plant clearing programmes DOI
Chad Cheney, Karen J. Esler, Llewellyn C. Foxcroft

et al.

Journal of Environmental Management, Journal Year: 2020, Volume and Issue: 271, P. 110836 - 110836

Published: June 25, 2020

Language: Английский

Citations

8
The ‘WATTLES’ Invasion Syndrome DOI
Ana Novoa, John R. Wilson, Johannes J. Le Roux

et al.

CABI eBooks, Journal Year: 2023, Volume and Issue: unknown, P. 514 - 525

Published: Nov. 13, 2023

The term 'invasion syndrome' refers to a combination of pathways, alien species' traits and characteristics the recipient ecosystem which collectively result in (invasions with) predictable dynamics impacts, that can be managed effectively using specific policy management actions. Grouping invasion events into syndromes thus allows for useful generalizations identification transferrable risk-assessment lessons across different contexts. In this chapter, we use information insights from chapters book argue invasions Australian Acacia species ('wattles') constitute distinct syndrome dub 'Woody Trees Transform landscapes: Leguminous, Enemy-free, with persistent Seed banks (WATTLES)' syndrome. WATTLES includes woody wattles form large long-lived seed are introduced high propagule pressure together their compatible rhizobia (or areas rhizobia) regions suitable climates lack specialist natural enemies. When happens, establish invasive populations modify hydrological, nutrient fire cycles invaded ecosystems, often leading invasional meltdown displacement native species. should prevented by carefully regulating or prohibiting deliberate introductions, and, once established, classical biocontrol supplemented physical chemical methods as needed, noting expensive active restoration efforts might required if goal is return system pre-invasion state. delimited chapter potentially extendable other legume events, such those Prosopis spp. Robinia pseudoacacia.

Language: Английский

Citations

2
An in vitro assessment of the potential antidiabetic activity and cytotoxic effects of ethanolic and aqueous extracts from three invasive Australian acacias DOI Creative Commons
Daniel Buttner, Shanika Reddy, Trevor Koekemoer

et al.

South African Journal of Botany, Journal Year: 2021, Volume and Issue: 141, P. 1 - 11

Published: May 12, 2021

Acacia cyclops, saligna and mearnsii are characterized as prolific invasive alien plants (IAPs) presenting a substantial ecological economic burden on South Africa. While conventionally these species perceived weeds having little value, this study attempts to demonstrate their respective potential phytomedicinal resource in the treatment of type 2 diabetes – thereby incentivizing eradication. Moreover, aimed assess antidiabetic cytotoxic effects extracts from three Australian acacias vitro. The α-glucosidase ɑ-amylase activities ethanolic aqueous derived aerial tissues A. saligna, were investigated, followed by cytotoxicity assessment using Hoechst 33342-Propidium Iodide (PI) dual staining quantitative fluorescence microscopy human colon (Caco-2) cell line. Of screened, bark demonstrated highest inhibitory activity against α-amylase with an IC50 10.45 ± 3.79 μg/ml 2.35 0.61 leaf extract depicting strong (IC50 3.64 1.59 μg/ml) moderate 17.67 3.84 inhibition. values all significantly (p < 0.05) lower than Acarbose 330.71 28.36 Epigallocatechin gallate 68.2 8.34 μg/ml). All found be nontoxic at test concentrations Caco-2 cells confirmed Hoescht 33342-PI staining. Overall, findings presented provide first concurrent account Acacias Africa reporting alternative therapeutic option for diabetes.

Language: Английский

Citations

4