Creatine Kinase Activity as an Indicator of Energetic Impairment and Tissue Damage in Fish: A Review

Fishes, Journal Year: 2023, Volume and Issue: 8(2), P. 59 - 59

Published: Jan. 18, 2023

Creatine kinase (CK) is an enzyme that produces and uses phosphocreatine to transfer energy maintain tissue cellular homeostasis, being considered the main controller of homeostasis. Its activity in plasma/serum has been commonly used evaluate damage, since CK released into bloodstream during damage. This review summarizes current knowledge regarding use fish, focusing on its potential as indicator impairment energetic homeostasis damage stressful situations, such exposure contaminants (metals, pesticides, microplastic), hypoxia, thermal stress, diseases (fungal, parasitic, bacterial). Based data, we can conclude be a suitable fish exposed different aquaculture challenge conditions, while serum/plasma first evidence possible due release bloodstream.

Language: Английский

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A Review on the Role of 2–8 Carbon Chain Carboxylates in Enhancing Aquaculture Performance

Reviews in Aquaculture, Journal Year: 2025, Volume and Issue: 17(1)

Published: Jan. 1, 2025

ABSTRACT Aquaculture is a key sector for global food security, but its sustainability and productivity remain constantly questioned. Using 2–8 carbon chain carboxylates (2–8 CCs) has proven to be promising beneficial strategy various fields, including aquaculture. Within the CCs, short‐chain fatty acids (SCFAs) have received significantly more attention from researchers than relatively less‐explored medium‐chain (MCFAs). Applying these compounds in aquaculture improved growth performance, feed efficiency, immune responses, intestinal health, antioxidant capacity, water quality, thus promoting organisms' sustainability. Furthermore, CCs offer significant environmental benefits by reducing reliance on antibiotics healthier gut microbiota, thereby mitigating some ecological impacts of They also contribute waste management practices developing circular economy within systems. This review comprehensively examines current understanding CCs' effects aquaculture, discussing their roles, impacts, benefits, challenges, future research directions. The findings underscore potential enhance systems, offering hopeful outlook field.

Language: Английский

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THE EFFECT OF THE PROBIOTIC “BACELL-M” ON THE MORPHOFUNCTIONAL STATE OF THE LIVER OF COMMON CARP (CYPRINUS CARPIO)

International Journal of Veterinary Medicine, Journal Year: 2025, Volume and Issue: 4, P. 144 - 151

Published: Jan. 16, 2025

Fish farming is one of the important branches agriculture. Success in this area largely depends on efficiency feed use, which makes rational feeding fish most aspects their breeding. The purpose study was to investigate changes morphofunctional state liver common carp (Cyprinus carpio) after inclusion probiotic “Bacell-M” diet. During experiment, market-size weighing 800-900 grams were used. For baseline research, biological material collected from across all experimental groups for cytomorphological analysis. divided into two main groups. first group (control, n=600) received a standard diet, while second (n=600) fed same diet supplemented with Bacell-M at dose 2 kg/ton 30 days. Slaughter and sampling (n=6) performed time points: 14 days 35 start experiment. results demonstrated that exerted positive effects, such as supporting integrity liver's vascular parenchymal structures, reducing lipid accumulation hepatocytes, decreasing inflammatory infiltrates, maintaining microcirculation within liver. To assess these we measured expression GPx-1 gene, plays key role cellular defense against oxidative stress.

Language: Английский

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Effect of dietary quercetin supplementation on high-starch diet-induced growth impairment, metabolic dysregulation, and oxidative stress in largemouth bass (Micropterus salmoides)

Aquaculture Reports, Journal Year: 2025, Volume and Issue: 41, P. 102704 - 102704

Published: Feb. 20, 2025

Language: Английский

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Ameliorative potential of Populus alba leaf powder against hexaflumuron exposure in Nile tilapia: immune-antioxidant, biochemical, histological, and transcriptomic analysis

Fish Physiology and Biochemistry, Journal Year: 2025, Volume and Issue: 51(2)

Published: March 14, 2025

Language: Английский

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Appropriate Fat Supplementation in High‐Starch Diets Involved in the Modification of Fatty Acids Profile, Amino Acids Composition, and Antioxidant Capacity of Adult Nile Tilapia (Oreochromis niloticus) Muscle

Aquaculture Nutrition, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Tilapia industry has faced great challenges due to the replacement of high‐quality protein sources by a high proportion starch. Meanwhile, level dietary fat is gradually reduced with increase oil price. High starch diets have been proved negative effects on flesh quality in previous studies, but remain unclear. The objective present study was ascertain whether requisite factor adult fish under conditions high‐starch diet feeding. involved Nile tilapia ( Oreochromis niloticus ) an initial body weight (IBW) 168.58 ± 2.01 g, which were fed standard (CON) diet, high‐starch‐low‐fat (HSLF) and high‐starch‐moderate‐fat (HSMF) for 10 weeks. results demonstrated that significantly decreased hardness, chewiness, springiness, gumminess muscle. HSLF led significant reduction gain rate (WGR), accompanied crude content decrease glycogen resulted levels polyunsaturated fatty acids (PUFAs), essential amino (EAAs), flavor (FAAs) muscle tissue. Furthermore, it influenced texture reducing collagen content, fiber density, sarcomere length. antioxidant capacity diminished affecting total (T‐AOC), catalase (CAT) activity, superoxide dismutase (SOD) as well expression related genes SOD , CAT nuclear erythroid 2 like nrf2 )). In contrast, HSMF did not detrimental impact growth performance, yet result hydroxyproline (Hyp), PUFAs, EAA, FAA Moreover, observed markedly elevate It can be concluded affect nutrients, decreasing capacity. Nevertheless, inclusion adequate quantity may prove effective means counteracting these unfavorable outcomes.

Language: Английский

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Unraveling the Disparity of Carbohydrate Utilization in Farmed Fish: Perspectives From Comparative Pancreatic Islet Biology

Reviews in Aquaculture, Journal Year: 2025, Volume and Issue: 17(3)

Published: April 1, 2025

ABSTRACT The potential benefits of enhancing the capacity for carbohydrate utilization in farmed fish, particularly species with pronounced intolerance, are significant from a number perspectives. In recent decades, multitude research initiatives have focused on elucidating factors that influence as well biological limitations constrain this process. Despite substantial progress achieved thus far, dearth clarity persists regarding associated tolerance among various species. Evidence suggests that, mammals, pancreatic islet tissues teleosts act regulatory valve glucose assimilation and metabolism. However, precise intricacies remain to be fully elucidated subject ongoing endeavors fish objective review is provide comprehensive evaluation extant gaps domain endocrinology, aim identifying potentially impede Furthermore, it incorporates advancements biology physiological functions homeostasis zebrafish model mammalian animals more overview future directions fish. addition, we present prospective avenues inquiry concomitant challenges achieve profound comprehension fundamental mechanisms precipitate intolerance This expected benefit researchers specializing study metabolism

Language: Английский

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Exposure to ambient UVB light influences the welfare, energy requirements, metabolism, and relevant molecular biology of a high-altitude fish Tor putitora: Investigating the hidden costs of sunlight in upland aquaculture

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742496 - 742496

Published: March 1, 2025

Language: Английский

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Dietary trehalose reduced liver glycogen accumulation and promoted protein deposition in hybrid grouper (Epinephelus fuscoguttatus ♀ × E. lanceolatus ♂) fed a high-carbohydrate diet

Aquaculture, Journal Year: 2025, Volume and Issue: unknown, P. 742544 - 742544

Published: April 1, 2025

Language: Английский

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Rainbow Trout (Oncorhynchus mykiss) Pre-Smolts Treated with 11-Deoxycorticosterone Regulate Liver Carbohydrate Metabolism and Gill Osmoregulation

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(8), P. 3725 - 3725

Published: April 15, 2025

Smoltification is stressful for salmonids, and cortisol one of the central endocrine regulators seawater adaptation. It has been established that plays both mineralocorticoid glucocorticoid functions by MR GR, respectively, since aldosterone hormone absent. Recently, investigations have proposed 11-deoxycorticosterone (DOC) precursor might support effects, but this mechanism remains unclear. Hence, we assessed early effects DOC on rainbow trout pre-smolts, key smoltification stage, via metabolic transcriptomic approaches. Thirty-six juveniles (~120 g) were treated 3 h with (1 mg/kg) and/or (eplerenone) or (mifepristone) receptor antagonists (n = 6 each group). decreased plasma glucose pyruvate increased phosphate liver glycogen. also downregulated carbohydrate metabolism-related genes in liver. Finally, gill RNA-seq analysis presented 1660 differentially expressed transcripts versus vehicle, 1022 eplerenone + 3324 mifepristone DOC. The enrichment mainly revealed upregulation ion transmembrane transport metabolism downregulation stress innate immune responses. This suggests a significant role osmoregulation pre-smolts through receptors. could contribute to improving animal welfare monitoring during featuring novel potential biomarkers.

Language: Английский

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