The Journal of Applied Poultry Research,
Journal Year:
2023,
Volume and Issue:
33(2), P. 100397 - 100397
Published: Dec. 15, 2023
The
chicken
gut
microbiota
plays
important
roles
in
host
physiology
and
well-being.
It
can
be
impacted
by
several
management
environmental
factors
like
the
use
of
antibiotic
growth
promoters
(AGP)
heat
stress
(HS).
Probiotics,
essential
oils
(EO),
vitamins
(such
as
folic
acid)
are
bioactive
substances
that
could
potentially
modulate
promote
its
resilience
to
stressful
factors,
especially
when
supplied
early
during
embryonic
development.
This
study
evaluated
modulating
potential
ovo
delivered
probiotics,
acid
(FA),
+
in-water
EO
broiler
chickens,
compared
an
in-feed
AGP,
under
HS
challenge.
Results
from
this
indicate
HS,
treatments
modified
ceca
bacterial
populations
suggest
microbiota-mediated
role
AGP
promotion
is
related
improved
biosynthesis
nutrients
(amino
acids
especially)
utilization
carbon
sources
derived
diet
microbiome.
Problemy biologii produktivnyh životnyh,
Journal Year:
2025,
Volume and Issue:
1, P. 57 - 66
Published: March 31, 2025
В
связи
с
принятием
в
РФ
законопроекта,
ограничивающего
использование
кормовых
антибиотиков
на
комплексах
по
выращиванию
животных,
настоящее
время
ведется
поиск
альтернативы
кормовым
антибиотикам,
частности,
применению
эфиромасличных
культур
кормлении
цыплят
бройлеров.
Цель
данной
работы
–
систематизация
данных
отечественных
и
зарубежных
исследований
изучению
свойств
фитобиотиков
эффективности
их
использования
при
выращивания
сельскохозяйственной
птицы
различных
направлений,
а
также
экономической
целесообразности
примененич
современном
птицеводстве.
Снижение
риска
развития
инфекционных
патологий
использовании
связывают
формированием
здоровой
микробиоты
пищеварительного
тракта,
которая
способна
обеспечить
высокую
резистентность
к
колонизации
кишечника
патогенами
благодаря
синтезу
летучих
жирных
кислот,
бактериоцинов
других
соединений,
сдерживающих
рост
развитие
патогенных
видов.
Ассортимент
отечественного
производства
пока
беден,
однако
последнее
начинается
идет
активное
продвижение
области
фитобиотических
добавок.
Основная
причина
отставания
является
низкий
уровень
внедрения
производство,
низкая
конкурентоспособность
технологий
высокоэффективных
добавок,
отсутствие
комплексных
сфере.
In
connection
with
the
adoption
in
Russian
Federation
of
a
bill
limiting
use
feed
antibiotics
animal
husbandry
complexes,
an
alternative
to
is
currently
being
sought,
particular,
essential
oil
crops
feeding
broiler
chickens.
The
purpose
this
work
systematize
data
domestic
and
foreign
studies
on
properties
phytobiotics
effectiveness
their
growing
agricultural
poultry
various
areas,
as
well
economic
feasibility
modern
farming.
reduction
risk
infectious
pathologies
when
using
associated
formation
healthy
microbiota
digestive
tract,
which
can
provide
high
resistance
intestinal
colonization
by
pathogens
due
synthesis
volatile
fatty
acids,
bacteriocins
other
compounds
that
inhibit
growth
development
pathogenic
species.
range
domestically
produced
still
poor,
but
recently
there
has
been
active
promotion
field
production
phytobiotic
additives.
main
reason
for
lag
low
level
implementation
production,
competitiveness
technologies
highly
effective
additives,
lack
comprehensive
area.
Poultry Science,
Journal Year:
2025,
Volume and Issue:
unknown, P. 105187 - 105187
Published: April 1, 2025
The
present
study
aimed
to
explore
the
effects
of
dietary
phloretin
(PT)
on
growth
performance,
immune
response,
and
intestinal
function
in
broilers
with
necrotic
enteritis
(NE).
A
total
288
1-day-old
Arbor
Acres
chicks
were
assigned
3
groups,
8
replicates
per
group
12
replicate.
Over
6
weeks,
birds
fed
a
basal
diet
or
same
supplemented
200
mg/kg
phloretin.
Birds
challenged
groups
inoculated
coccildia
during
d
7
9
Clostridium
perfringens(CP)
14
18.
Results
showed
that
CP
coccidia
challenge
reduced
average
daily
gain
feed
intake,
increased
conversion
ratio
broilers,
induced
inflammation
oxidative
stress,
inhibited
mRNA
expression
levels
for
genes
associated
barrier
nutrient
transporters
(P
<
0.05).
PT
addition
improved
performance
at
early
phase
morphology,
elevated
antioxidant
capacity
via
increasing
activity
superoxide
dismutase
ileum
0.01).
Dietary
regulated
intesetinal
as
observed
by
increases
content
secretory
IgA
decreased
cytokines
(Interleukin-1β,
Interleukin-10)
Moreover,
NE
infection
significantly
disrupted
balance
flora,
led
lower
level
short-chain
fatty
acids
such
butyric
acid
concentration
ileum,
while
microbiota
structure,
acetic
0.001).
Furthermore,
metabolomics
analysis
indicated
treatment
improve
plant
secondary
metabolites
contents
like
2'-o-glucuronide.
Additionally,
we
significant
positive
correlation
among
PT,
Ligilactobacillus
acid,
between
metabolites.
Overall,
supplementation
could
ameliorate
injury
enhancing
function,
regulating
flora
structure
producing
Animals,
Journal Year:
2025,
Volume and Issue:
15(3), P. 299 - 299
Published: Jan. 21, 2025
Intestinal
disease
is
becoming
increasingly
prevalent
in
poultry
production;
however,
the
effect
of
BEC
laying
hens
challenged
with
C.
perfringens
and
coccidia
limited.
This
study
aimed
to
investigate
effects
dietary
supplementation
on
intestinal
ovarian
health
coccidia.
A
total
80
Lohmann
gray
(35
weeks)
were
randomly
assigned
two
groups
supplemented
(0
or
1000
mg/kg).
Each
group
contained
40
replicates,
one
bird
each
(one
hen
per
cage).
During
sixth
week
trial,
half
(n
=
20)
administered
mL
(2.5
×
1010
CFU/mL)
0.15
(55,000
sporangia/mL),
while
other
phosphate-buffered
saline
(PBS).
The
results
indicated
that
those
had
severely
damaged
jejunal
histopathological
morphology,
increased
oxidative
damage,
decreased
cecal
acetic
acid
butyric
content
(p
<
0.05),
resulted
lower
gut
microbial
richness
diversity.
diet
mg/kg
reduced
pathological
damage
short-chain
fatty
acids
(SCFAs)
content,
enhanced
diversity
0.05)
Furthermore,
positive
associated
changes
composition
structure.
In
summary,
has
potential
reduce
severity
caused
by
challenges
posed
through
modulation
microbiota.
Animals,
Journal Year:
2022,
Volume and Issue:
12(7), P. 892 - 892
Published: March 31, 2022
In
poultry,
severe
gastrointestinal
diseases
are
caused
by
bacteria
and
coccidia,
with
important
economic
losses
in
the
poultry
industry
requirement
of
treatments
which,
for
years,
were
based
on
use
antibiotics
chemotherapies.
Furthermore,
Salmonella
spp.,
Clostridium
perfringens,
Campylobacter
jejuni
can
cause
serious
foodborne
people,
resulting
from
consumption
meat,
eggs,
derived
products.
With
spread
antibiotic
resistance,
which
affects
both
animals
humans,
restriction
livestock
production
identification
a
list
“critically
antimicrobials”
became
necessary.
For
this
reason,
researchers
focused
natural
compounds
effective
alternatives
to
prevent
disease
poultry.
This
review
summarizes
results
several
studies
published
last
decade,
describing
different
nutraceutical
or
phytonutrients
industry.
The
these
products
not
always
encouraging.
While
some
have
proven
be
very
promising,
further
will
needed
verify
efficacy
practical
applicability
other
compounds.
Italian Journal of Animal Science,
Journal Year:
2022,
Volume and Issue:
21(1), P. 792 - 801
Published: April 25, 2022
This
study
was
conducted
to
evaluate
the
potential
growth
and
health
promotion
of
Rumex
nervosus
leaves
(RNL)
Cinnamomum
verum
bark
(CVB)
supplementation
as
phytogenic
promoters
on
broilers.
For
34
days,
540
day-old
broiler
chicks
were
randomly
assigned
nine
groups.
Birds
fed
basal
diet
supplemented
with
1,
3,
or
5
g/kg
RNL,
2,
4,
6
CVB.
In
addition,
birds
complemented
antibiotic
(AGP),
without
feed
additive
controls.
All
bird
vaccinated
for
IBV,
IBDV,
NDV
except
negative
control
(NC).
The
selected
indicators
measured
analysed.
Broilers
given
1
g
RNL
numerically
heavier
at
days
gained
more
a
degree
comparable
AGP
group
(p
=
.053).
addition
CVB
2
resulted
in
best-feed
conversion
up
21
d
.04).
Throughout
study,
dietary
treatments
had
no
impact
intake.
Except
ALT,
none
immune-related
parameters
serum
biochemical
profile
differed
statistically
between
when
compared
group.
When
comparing
non-vaccinated
un-treated
day
34,
vaccination
increased
significantly
antibody
titres
IBDV.
conclusion,
CVB,
especially
low
doses,
attempted
maximise
performance
compromising
chickens
under
typical
conditions.
Further
research
into
use
natural
herbs
challenging
conditions
is
required
performance,
maintain
animal
productivity,
achieve
ultimate
goal
reducing
poultry
industry.
HighlightsCinnamomum
dose
improved
ratio
during
starter
period.
However,
both
result
unsatisfactory
improvements
overall
period
ideal
hygienic
conditions.If
broilers
are
exposed
bacterial
challenges,
additives
even
antibiotics
may
manifest
their
activity
promoting
and,
result,
performance.Low
levels
hepatic
enzymes
age
showed
that
birds'
good.Cinnamon
powder
improves
kidney
function
by
lowering
creatinine
increasing
<
.05).Rumex
have
hypoglycaemia
31
glucose
reduced.
Animal Husbandry and Fodder Production,
Journal Year:
2022,
Volume and Issue:
105(1), P. 103 - 118
Published: Jan. 1, 2022
Аннотация.Обеспечение
нормализации
показателей
гомеостаза,
а
также
повышение
продуктивности
в
условиях
промышленных
технологий
невозможны
без
полной
реализации
генетического
потенциала,
на
что
свою
очередь
влияет
введение
состав
рациона
биологически
активных
добавок.Биологически
активные
соединения,
полученные
из
растений,
то
есть
фитобиотики,
являются
одной
альтернатив
антибиотикам
птицеводстве
и
животноводстве,
благодаря
свойственной
им
антимикробной
активности
положительного
воздействия
микробиом
кишечника,
динамики
продуктивности.Комплексное
применение
фитобиотиков
с
микроэлементами
пробиотиками,
свежие
или
высушенные
растения,
их
смеси,
используют
для
интерьерные
экстерьерные
показатели
животных.Вопрос
востребованности
применения
естественных
кормовых
добавок
занимает
далеко
не
последнее
место.Противодействие
микробным
элементам
-основные
причины
использования
животноводстве.Вследствие
фитобиотических
препаратов
отмечают
высокий
коэффициент
конверсии
корма
противовоспалительное
действие.Повышение
качества
жизни
населения
производство
экологически
чистой
продукции
сельского
хозяйства
важными
факторами
при
разработке
Journal of Poultry Sciences and Avian Diseases,
Journal Year:
2024,
Volume and Issue:
2(2), P. 36 - 49
Published: Jan. 1, 2024
The
global
poultry
industry
relies
heavily
on
antibiotics
to
prevent
and
treat
diseases
promote
growth.
However,
the
rise
of
antibiotic-resistant
bacteria
poses
significant
risks
both
animal
human
health,
necessitating
alternative
approaches
maintain
health
productivity.
This
review
systematically
examines
evidence
for
medicinal
plants
their
bioactive
components
as
non-antibiotic
interventions
growth
promoters
in
species.
Numerous
herbs,
spices,
plant
extracts,
essential
oils,
isolated
phytochemicals
demonstrate
beneficial
bioactivities
relevant
production
vitro
vivo,
including
antimicrobial,
anti-inflammatory,
immunomodulatory,
antioxidant
effects.
While
considerable
research
confirms
positive
impacts
performance
under
experimental
conditions,
questions
remain
regarding
bioavailability,
mechanisms,
efficacy,
safety,
feasibility,
suitability
commercial
integration
that
currently
impede
widespread
adoption
antibiotic
alternatives.
Further
high-quality
controlled
trials
directly
analyzing
physiological
responses,
impacts,
safety
profiles,
cost-effectiveness
analysis
are
warranted
support
evidence-based
phytogenic
feed
additives
systems.
Poultry Science,
Journal Year:
2023,
Volume and Issue:
102(6), P. 102675 - 102675
Published: March 29, 2023
The
effects
of
concurrent
reduction
dietary
metabolizable
energy
(ME)
and
crude
protein
(CP)
levels
combined
or
not
with
the
inclusion
a
phytogenic
feed
additive
(PFA)
were
studied
using
nutrigenomics
approach.
In
particular,
expression
26
critical
genes
relevant
for
inflammation
control
(TLR
pathway),
cellular
apoptosis
(MAPK
pathway)
cell
growth
nutrient
metabolism
(PI3K-Akt-mTOR
was
profiled
along
broiler
intestine.
Two
types
(L
H)
differing
in
(L:
95%
H:
100%
optimal
Cobb
500
recommendations
ME
CP
requirements)
supplemented
PFA
(−
+)
their
interactions
(L−,
L+,
H−,
H+)
evaluated.
There
only
3
total
(mTOR,
IL8,
HRAS
P
<
0.05)
between
diet
type
indicating
limited
effects.
Diet
type,
L
upregulated
related
mainly
jejunum,
ileum,
cecum
(P
MAPK
pathway
ileum
0.05).
Moreover,
negatively
affected
to
PI3K-Akt-mTOR
duodenum
On
other
hand,
downregulated
TLR
signaling
(TLR2B,
MyD88,
TLR3,
LITAF)
intestine
(APO1,
FOS)
jejunum
Finally,
supplementation
regulated
sensing
manner
perceived
as
beneficial
growth.
conclusion,
study
results
highlight
that
reduced
specifications,
especially
absence
PFA,
regulate
inflammation,
processes
at
homeostatic
hinder
maximizing
availability
nutrients
purposes.
Inclusion
helped
adjust
respective
responses
supporting
performance,
specification
diets.