Identifying Antimicrobial Agents from Chlorella sorokiniana: A Biotechnological Approach Utilizing Eco-Friendly Extraction and Characterization Methods DOI Creative Commons
Elia Lio, Martina Dramis, Gianluca Ottolina

et al.

BioTech, Journal Year: 2025, Volume and Issue: 14(1), P. 22 - 22

Published: March 18, 2025

Natural compounds are increasingly favored over synthetic ones for their lower environmental impact. However, extraction and characterization processes typically rely on harsh conditions conventional solvents, which unsustainable cause pollution. This study aimed to develop an eco-friendly method isolate evaluate the antimicrobial properties of bioactive from Chlorella sorokiniana. Using dimethyl carbonate (DMC), methoxycyclopentane (CPME), butan-2-one (MEK) as green solvents alongside chloroform a non-green reference solvent, both untreated sodium hydroxide pre-treated microalgae biomass, extract yields up 182 ± 27 mg/g DW were obtained using MEK. Extracts biomass exhibited MIC values compared those with same solvent when tested agents against Escherichia coli, Bacillus megaterium, subtilis. The lowest value (4.89 0.05 µg/mL) was observed E. coli CPME, comparable vancomycin control (1.55 0.03 µg/mL). Principal component analysis highlighted correlations between GC-MS-identified activity. ANOVA post hoc tests (p < 0.05) confirmed choice, pre-treatment influenced yield bioactivity. results underscore sustainable alternatives extracting autotrophic microalgae.

Language: Английский

Antibacterial and Biopriming Effects of Nostocales Cyanobacteria on Tomato Plants Infected with Bacterial Spot Disease DOI
Sajjad Ghahari, Ghorbanali Nematzadeh, Ali Pakdin‐Parizi

et al.

Current Microbiology, Journal Year: 2025, Volume and Issue: 82(5)

Published: March 31, 2025

Language: Английский

Citations

0
Harnessing microalgae as a bioresource for nutraceuticals: advancing bioactive compound exploration and shaping the future of health and functional food innovation DOI Creative Commons

Anjuman Ayub,

Farida Rahayu, Aniswatul Khamidah

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 7(5)

Published: April 23, 2025

Language: Английский

Citations

0
Identifying Antimicrobial Agents from Chlorella sorokiniana: A Biotechnological Approach Utilizing Eco-Friendly Extraction and Characterization Methods DOI Creative Commons
Elia Lio, Martina Dramis, Gianluca Ottolina

et al.

BioTech, Journal Year: 2025, Volume and Issue: 14(1), P. 22 - 22

Published: March 18, 2025

Natural compounds are increasingly favored over synthetic ones for their lower environmental impact. However, extraction and characterization processes typically rely on harsh conditions conventional solvents, which unsustainable cause pollution. This study aimed to develop an eco-friendly method isolate evaluate the antimicrobial properties of bioactive from Chlorella sorokiniana. Using dimethyl carbonate (DMC), methoxycyclopentane (CPME), butan-2-one (MEK) as green solvents alongside chloroform a non-green reference solvent, both untreated sodium hydroxide pre-treated microalgae biomass, extract yields up 182 ± 27 mg/g DW were obtained using MEK. Extracts biomass exhibited MIC values compared those with same solvent when tested agents against Escherichia coli, Bacillus megaterium, subtilis. The lowest value (4.89 0.05 µg/mL) was observed E. coli CPME, comparable vancomycin control (1.55 0.03 µg/mL). Principal component analysis highlighted correlations between GC-MS-identified activity. ANOVA post hoc tests (p < 0.05) confirmed choice, pre-treatment influenced yield bioactivity. results underscore sustainable alternatives extracting autotrophic microalgae.

Language: Английский

Citations

0