Comprehensive insights into mechanism of nanotoxicity, assessment methods and regulatory challenges of nanomedicines

Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)

Published: Oct. 4, 2024

Nanomedicine has the potential to transform healthcare by offering targeted therapies, precise diagnostics, and enhanced drug delivery systems. The National Institutes of Health coined term "nanomedicine" describe use nanotechnology in biological system monitoring, control, diagnosis, treatment. continues receive increasing interest for rationalized therapeutics pharmaceutical agents achieve required response while reducing its side effects. However, as advance, concerns about toxicological effects have also grown. This review explores current state nanomedicine, focusing on types nanoparticles used their associated properties that contribute nanotoxicity. It examines mechanisms through which exert toxicity, encompassing various cellular molecular interactions. Furthermore, it discusses assessment methods employed evaluate nanotoxicity, in-vitro in-vivo models, well emerging techniques. addresses regulatory issues surrounding nanotoxicology, highlighting challenges developing standardized guidelines ensuring secure translation nanomedicine into clinical settings. ethical with understanding safety profile is essential effective therapeutic applications.

Language: Английский

Iron oxide Nanoparticles Enhancing Magnetic Resonance Imaging: A Review of the Latest Advancements

Journal of Science Advanced Materials and Devices, Journal Year: 2025, Volume and Issue: unknown, P. 100875 - 100875

Published: March 1, 2025

Language: Английский

Application and Safety Research of Nanotechnology in Cosmetics: Current Status, Challenges, and Future Prospects

BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)

Published: March 22, 2025

Language: Английский