Study of green-synthesized Ag–Ca–kaolin composite for hemostatic and antibacterial effect DOI

Karthikeyan Kumarasamy,

Rama V. Ramachandran,

Manisha Vidyavathy Sundaradoss

et al.

Green Materials, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 8

Published: April 24, 2025

This research introduces a novel kaolin-based composite enriched with calcium and green-synthesized silver nanoparticles (Ag NPs) to achieve enhanced hemostatic antibacterial properties, addressing limitations of current agents. The composite’s synthesis utilized an eco-friendly approach, incorporating for improved hemostasis Ag NPs broad-spectrum activity. Detailed characterization using Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy-dispersive confirmed the successful integration components their distribution within kaolin matrix. Hemostatic efficacy was evaluated through blood clotting time analysis, revealing 112-s 1% loading, which varied concentration. Antibacterial performance, assessed against Escherichia coli Staphylococcus aureus well diffusion method, demonstrated increasing inhibition zones higher content, peaking at 17.8 ± 1.4 mm 5% Ag. These findings establish potential this as effective blood-clotting agent potent offering promising solution traumatic hemorrhage control in diverse medical applications, including battlefield trauma care surgical procedures.

Language: Английский

Study of green-synthesized Ag–Ca–kaolin composite for hemostatic and antibacterial effect DOI

Karthikeyan Kumarasamy,

Rama V. Ramachandran,

Manisha Vidyavathy Sundaradoss

et al.

Green Materials, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 8

Published: April 24, 2025

This research introduces a novel kaolin-based composite enriched with calcium and green-synthesized silver nanoparticles (Ag NPs) to achieve enhanced hemostatic antibacterial properties, addressing limitations of current agents. The composite’s synthesis utilized an eco-friendly approach, incorporating for improved hemostasis Ag NPs broad-spectrum activity. Detailed characterization using Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, energy-dispersive confirmed the successful integration components their distribution within kaolin matrix. Hemostatic efficacy was evaluated through blood clotting time analysis, revealing 112-s 1% loading, which varied concentration. Antibacterial performance, assessed against Escherichia coli Staphylococcus aureus well diffusion method, demonstrated increasing inhibition zones higher content, peaking at 17.8 ± 1.4 mm 5% Ag. These findings establish potential this as effective blood-clotting agent potent offering promising solution traumatic hemorrhage control in diverse medical applications, including battlefield trauma care surgical procedures.

Language: Английский

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