The nano-paradox: addressing nanotoxicity for sustainable agriculture, circular economy and SDGs DOI Creative Commons

Vijay Rani Rajpal,

Byonkesh Nongthongbam,

Manika Bhatia

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 24, 2025

Engineered nanomaterials (ENMs) have aroused extensive interest in agricultural, industrial, and medical applications. The integration of ENMs into the agricultural systems aligns with principles United Nations' sustainable development goals (SDGs), circular economy (CE) bio-economy (BE) principles. This approach offers excellent opportunities to enhance productivity address global climate change challenges. revelation adverse effects (NMs) on various organisms ecosystems, however, has fueled debate 'Nano-paradox' leading emergence a new research domain 'Nanotoxicology'. shown different interactions biological environmental as compared their bulk counterparts. They bioaccumulate organisms, soils, other matrices, move through food chains reach higher trophic levels including humans ultimately resulting oxidative stress cellular damage. Understanding nano-bio interactions, mechanism gene- cytotoxicity, associated potential hazards, is therefore, essential mitigate toxicological outputs. review comprehensively examines cyto- genotoxicity mechanisms systems, covering aspects such entry, uptake, responses, dynamic environments long-term risk assessment (ERA). It also discusses methods, regulatory policies, strategies for toxicity management/mitigation future directions nanotechnology, all within context SDGs, CE, promoting resource efficiency sustainability. Navigating nano-paradox involves balancing benefits concerns about nanotoxicity. Prioritizing thorough above facets can ensure sustainability safety, enabling responsible harnessing nanotechnology's transformative applications mitigating enhancing productivity.

Language: Английский

The nano-paradox: addressing nanotoxicity for sustainable agriculture, circular economy and SDGs DOI Creative Commons

Vijay Rani Rajpal,

Byonkesh Nongthongbam,

Manika Bhatia

et al.

Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 24, 2025

Engineered nanomaterials (ENMs) have aroused extensive interest in agricultural, industrial, and medical applications. The integration of ENMs into the agricultural systems aligns with principles United Nations' sustainable development goals (SDGs), circular economy (CE) bio-economy (BE) principles. This approach offers excellent opportunities to enhance productivity address global climate change challenges. revelation adverse effects (NMs) on various organisms ecosystems, however, has fueled debate 'Nano-paradox' leading emergence a new research domain 'Nanotoxicology'. shown different interactions biological environmental as compared their bulk counterparts. They bioaccumulate organisms, soils, other matrices, move through food chains reach higher trophic levels including humans ultimately resulting oxidative stress cellular damage. Understanding nano-bio interactions, mechanism gene- cytotoxicity, associated potential hazards, is therefore, essential mitigate toxicological outputs. review comprehensively examines cyto- genotoxicity mechanisms systems, covering aspects such entry, uptake, responses, dynamic environments long-term risk assessment (ERA). It also discusses methods, regulatory policies, strategies for toxicity management/mitigation future directions nanotechnology, all within context SDGs, CE, promoting resource efficiency sustainability. Navigating nano-paradox involves balancing benefits concerns about nanotoxicity. Prioritizing thorough above facets can ensure sustainability safety, enabling responsible harnessing nanotechnology's transformative applications mitigating enhancing productivity.

Language: Английский

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